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Application of nauclea officinalis extract in preparation of medicine for preventing and treating oral ulcer diseases

A technology of oral ulcers and extracts, applied in the field of pharmacy, can solve the problems of no bilewood oral ulcers, no bilewood prevention and treatment of oral ulcers, etc., and achieve the effect of promoting ulcer tissue repair

Pending Publication Date: 2022-04-15
海南医学院第二附属医院 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no relevant report on the treatment of oral ulcers by bilewood, and no relevant reports on the prevention and treatment of oral ulcers by bilewood.

Method used

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  • Application of nauclea officinalis extract in preparation of medicine for preventing and treating oral ulcer diseases
  • Application of nauclea officinalis extract in preparation of medicine for preventing and treating oral ulcer diseases
  • Application of nauclea officinalis extract in preparation of medicine for preventing and treating oral ulcer diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] 400 g of gallbladder, 4000 ml of acid water was added, and the heat reflux was added twice, and the filtrate was collected each time, the filtrate was collected, the mixture was concentrated to 1: 2 (medicinal material: extract), gallbladderum extract.

Embodiment 2

[0019] 400 g of gallbladder, 4800 ml of water was added, and the reflux was added twice, and the filtrate was collected, the filtrate was collected, the mixture was mixed, and the pressure was concentrated to a thick paste.

Embodiment 3

[0021] 400 g of gallbladderousum was added, 5600 ml of water was added, and the reflux was added twice, and the filtrate was collected, the filtrate was collected, and the mixture was concentrated to a thick paste.

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PUM

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Abstract

The invention discloses an application of a nauclea officinalis extract in preparation of a medicine for preventing and treating oral ulcer. The new application of the nauclea officinalis extract is developed through a large number of experimental screening, and experimental results show that the nauclea officinalis extract can promote phosphorylation of AKT and PI3K in rat oral ulcer tissue and has a good effect of promoting ulcer tissue repair.

Description

Technical field [0001] The present invention relates to a new use of bilechi-alkali extract, and specifically, the application of gallbladder extracts in the prevention and treatment of oral ulcer diseases, and is a pharmaceutical technology. Background technique [0002] Nauclea Officinalis Pierre EX PITARD is the 科 科 檀, 又 乌 树Used to treat pharyngitis, bronchitis, acute tonsillitis, etc., "plant antibiotics", mainly distributed in Hainan, Guangdong, Guangxi and other places. [0003] Oral ulcers are clinically common diseases, multiplexation, per capita diseases in different age groups, and foreign investigation and research have shown that the general population is about 60%, and the prevalence of Switzerland is 17.7%. Although the ulcer clinical incidence is high, modern medicine is still unknown, no ideal treatment, and is mainly symptomatic treatment, and is divided into whole-body treatment and local medication. The whole body treatment is mainly used immunomodulators, lipo...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61P1/02
Inventor 贺小宁李永辉李爱玲钟晓雪王慧薛逢明吴文智陈龙陈垂壮梁昌富
Owner 海南医学院第二附属医院
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