Application of a kind of traditional Chinese medicine combination in the preparation of medicine for treating chronic gout

Abstract

The invention provides application of a Chinese medicine composition to the preparation of medicine for treating chronic gout. The Chinese medicine composition is prepared by polygonum cuspidatum, semen plantaginis, caulis piperis futokadsurae, pyrola, radix curcuma, caulis spatholobi, rhizoma dioscoreae and semen cuscutae through water extraction. The Chinese medicine composition has the advantages that the polygonum cuspidatum and the semen plantaginis having the effect of clearing heat and promoting diuresis are used as the monarch drugs, the caulis piperis futokadsurae and the pyrola having the effect of dispelling wind and removing meridian obstruction are used as the ministerial drugs, the radix curcuma and the caulis spatholobi having the effect of promoting blood circulation to arrest pain and the rhizoma dioscoreae and the semen cuscutae having effects of tonifying qi and the spleen and nourishing the liver and the kidney are also used, and the Chinese medicine composition has an evident curative effect on the gout and hyperuricemia and is low in toxic and side effect and suitable for being taken by a patient for a long time.

Description

Technical field

[0001] The invention relates to the use of a traditional Chinese medicine composition in preparing a medicine for treating chronic gout, and belongs to the application field of traditional Chinese medicine. Background technique

[0002] Gout is a characteristic joint inflammation caused by the disorder of purine metabolism and increased blood uric acid, which leads to the deposition of uric acid crystals in the joints and surrounding tissues. Clinically, it is characterized by hyperuricemia, recurrent episodes of characteristic acute arthritis, and formation of gout stones. In severe cases, it can cause joint deformities and dysfunction, acute obstructive nephropathy or gouty nephropathy. In recent years, due to the improvement of people's living standards and changes in dietary structure, the incidence of gout has increased year by year. With the continuous research on the pathogenesis of gout, many gout treatment drugs have also been discovered in the process. ...

Examples

Embodiment 1

[0022] (1) According to 18 parts of Polygonum cuspidatum, 16 parts of Plantago sylvestris, 12 parts of Sea Breeze Thorn, 12 parts of Ceratophyllum serrata, 11 parts of Turmeric, 9 parts of Spatholobus spatholobi, 8 parts of Chinese yam, and 9 parts of Cuscuta, Chinese medicinal materials are weighed and selected. Crush into coarse powder for use;

[0023] (2) Add 10 times the amount of water to the coarse powder obtained in step (1), heat it to boiling, simmer for 3.5 hours, filter to obtain the filtrate, add the filter residue to 8 times water and cook twice, each time for 3 hours, filter , Combine the filtrate, concentrate it to a thick paste, place it in a vacuum drying oven, and dry at 65°C to obtain a dry extract. The dry extract is pulverized into fine powder and passed through a 300-mesh sieve for use;

[0024] (3) The fine powder obtained in step (3) is added to an appropriate amount of magnesium stearate and made into soft material with starch slurry, passed through a 20-m...

Embodiment 2

[0026] (1) According to 20 parts of Polygonum cuspidatum, 15 parts of Plantago Seed, 15 parts of Sea Breeze Vine, 10 parts of Ceratophyllum, 9 parts of Turmeric, 10 parts of Spatholobus, 10 parts of Chinese Yam, and 10 parts of Cuscuta, Chinese medicinal materials are weighed and selected. Crush into coarse powder for use;

[0027] (2) Add 11 times the amount of water to the coarse powder obtained in step (1), heat it to boiling, simmer for 4 hours, filter to obtain the filtrate, add 9 times water to the filter residue and decoc 2 times for 3.5 hours each time, filter , Combine the filtrate, concentrate it to a thick paste, place it in a vacuum drying oven, and dry at 70°C to obtain a dry extract. The dry extract is pulverized into fine powder and passed through a 300-mesh sieve for use;

[0028] (3) The fine powder obtained in step (3) is added to an appropriate amount of magnesium stearate and made into soft material with starch slurry, passed through a 20-mesh sieve, and granula...

Embodiment 3

[0030] (1) According to 15 parts of Polygonum cuspidatum, 12 parts of Plantago sylvestris, 10 parts of Sea Breeze Vinegar, 11 parts of Cervus serrata, 12 parts of Turmeric, 8 parts of Spatholobus, 6 parts of Chinese yam, 8 parts of Cuscuta, Chinese medicinal materials are weighed and selected. Crush into coarse powder for use;

[0031] (2) Add 9 times the amount of water to the coarse powder obtained in step (1), heat it to boiling, simmer for 3 hours, filter to obtain the filtrate, add the filter residue to 7 times water and decoc 2 times for 2.5 hours each time, filter , Combine the filtrate, concentrate it to a thick paste, place it in a vacuum drying oven, and dry at 65°C to obtain a dry extract. The dry extract is pulverized into fine powder and passed through a 300-mesh sieve for use;

[0032] (3) The fine powder obtained in step (3) is added to an appropriate amount of magnesium stearate and made into soft material with starch slurry, passed through a 20-mesh sieve, and gran...

Technical field

[0001] The invention relates to the use of a traditional Chinese medicine composition in preparing a medicine for treating chronic gout, and belongs to the application field of traditional Chinese medicine. Background technique

[0002] Gout is a characteristic joint inflammation caused by the disorder of purine metabolism and increased blood uric acid, which leads to the deposition of uric acid crystals in the joints and surrounding tissues. Clinically, it is characterized by hyperuricemia, recurrent episodes of characteristic acute arthritis, and formation of gout stones. In severe cases, it can cause joint deformities and dysfunction, acute obstructive nephropathy or gouty nephropathy. In recent years, due to the improvement of people's living standards and changes in dietary structure, the incidence of gout has increased year by year. With the continuous research on the pathogenesis of gout, many gout treatment drugs have also been discovered in the process. ...

Examples

Embodiment 1

[0022] (1) According to 18 parts of Polygonum cuspidatum, 16 parts of Plantago sylvestris, 12 parts of Sea Breeze Thorn, 12 parts of Ceratophyllum serrata, 11 parts of Turmeric, 9 parts of Spatholobus spatholobi, 8 parts of Chinese yam, and 9 parts of Cuscuta, Chinese medicinal materials are weighed and selected. Crush into coarse powder for use;

[0023] (2) Add 10 times the amount of water to the coarse powder obtained in step (1), heat it to boiling, simmer for 3.5 hours, filter to obtain the filtrate, add the filter residue to 8 times water and cook twice, each time for 3 hours, filter , Combine the filtrate, concentrate it to a thick paste, place it in a vacuum drying oven, and dry at 65°C to obtain a dry extract. The dry extract is pulverized into fine powder and passed through a 300-mesh sieve for use;

[0024] (3) The fine powder obtained in step (3) is added to an appropriate amount of magnesium stearate and made into soft material with starch slurry, passed through a 20-m...

Embodiment 2

[0026] (1) According to 20 parts of Polygonum cuspidatum, 15 parts of Plantago Seed, 15 parts of Sea Breeze Vine, 10 parts of Ceratophyllum, 9 parts of Turmeric, 10 parts of Spatholobus, 10 parts of Chinese Yam, and 10 parts of Cuscuta, Chinese medicinal materials are weighed and selected. Crush into coarse powder for use;

[0027] (2) Add 11 times the amount of water to the coarse powder obtained in step (1), heat it to boiling, simmer for 4 hours, filter to obtain the filtrate, add 9 times water to the filter residue and decoc 2 times for 3.5 hours each time, filter , Combine the filtrate, concentrate it to a thick paste, place it in a vacuum drying oven, and dry at 70°C to obtain a dry extract. The dry extract is pulverized into fine powder and passed through a 300-mesh sieve for use;

[0028] (3) The fine powder obtained in step (3) is added to an appropriate amount of magnesium stearate and made into soft material with starch slurry, passed through a 20-mesh sieve, and granula...

Embodiment 3

[0030] (1) According to 15 parts of Polygonum cuspidatum, 12 parts of Plantago sylvestris, 10 parts of Sea Breeze Vinegar, 11 parts of Cervus serrata, 12 parts of Turmeric, 8 parts of Spatholobus, 6 parts of Chinese yam, 8 parts of Cuscuta, Chinese medicinal materials are weighed and selected. Crush into coarse powder for use;

[0031] (2) Add 9 times the amount of water to the coarse powder obtained in step (1), heat it to boiling, simmer for 3 hours, filter to obtain the filtrate, add the filter residue to 7 times water and decoc 2 times for 2.5 hours each time, filter , Combine the filtrate, concentrate it to a thick paste, place it in a vacuum drying oven, and dry at 65°C to obtain a dry extract. The dry extract is pulverized into fine powder and passed through a 300-mesh sieve for use;

[0032] (3) The fine powder obtained in step (3) is added to an appropriate amount of magnesium stearate and made into soft material with starch slurry, passed through a 20-mesh sieve, and gran...

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