Small bioreactor paddle angle regulator and regulating assembly

Abstract

The utility model relates to the technical field of biological medicine, in particular to a paddle angle regulator and a paddle angle regulating assembly of a small bioreactor. The paddle angle regulator of the small bioreactor comprises a base, a center scale part is arranged on the base and is perpendicular to the base, the paddle angle regulator further comprises a limiting caliper assembly, the limiting caliper assembly comprises a circular ring and a clamping strip arranged in the diameter direction of the circular ring, the circular ring is parallel to the base, and the clamping strip is arranged on the base. The clamping strip is connected with the central scale part, and the clamping strip can slide along the height direction relative to the central scale part. According to the utility model, the stirring paddle is sleeved on the central scale part, and the height of the paddle is limited by moving the limiting caliper assembly according to the required paddle angle, so that the aim of adjusting the paddle angle is fulfilled.

Description

Technical Field

[0001] The utility model relates to the technical field of biomedicine, in particular to a blade angle regulator and a regulating component of a small bioreactor. Background Art

[0002] At present, in the process of cell culture process development in the biopharmaceutical field, various types of bioreactors are used for process research, and the stirring paddles equipped with the reactors are also different. The blades are also divided into two types: angle-adjustable and angle-non-adjustable. When developing cell culture processes, when studying gas transfer characteristics and shear stress applied to cells, the angle of the blade is used as a geometric parameter and included in the assessment indicators. At this stage, there are no corresponding adjustment tools for adjusting the blade angle. Usually, it is necessary to find a manufacturer to customize it, or measure it with a triangle ruler. Finding a manufacturer to customize it not only takes a long time, but also requires various angles to be equipped to meet the screening conditions, which is expensive. Measuring with a triangle ruler has low accuracy and large differences in personnel operations. Both of the above methods have some disadvantages and limitations. Utility Model Content

[0003] In view of the shortcomings of the prior art mentioned above, the purpose of the utility model is to provide a small bioreactor blade angle adjuster and adjustment assembly, the stirring paddle is placed on the central scale part, and the limit caliper assembly is moved according to the required blade angle to limit the blade height and achieve the purpose of adjusting the blade angle.

[0004] To achieve the above-mentioned purpose and other related purposes, the utility model provides a small bioreactor blade angle adjuster, including a base, a center scale portion is provided on the base, the center scale portion is perpendicular to the base, and also includes a limit caliper assembly, the limit caliper assembly includes a circular ring and a clamping strip arranged along the diameter direction of the circular ring, the circular ring is arranged parallel to the base, the clamping strip is connected to the center scale portion, and the clamping strip can slide back and forth in the height direction relative to the center scale portion, and is suitable for adjusting the angle of the blade by sliding the clamping strip to make the circular ring contact the blade and limit the blade height.

[0005] In some embodiments of the present invention, a scale is provided on the central scale portion.

[0006] In some embodiments of the present invention, the scale size of the scale ruler gradually increases from the end close to the base toward the top of the central scale portion.

[0007] In some embodiments of the present invention, a slide rail is provided on the central scale portion extending in the height direction, and the clamping strip can slide along the slide rail.

[0008] In some embodiments of the present invention, the size of the clamping strip is equal to the size of the slide rail.

[0009] In some embodiments of the present invention, the bottom end of the central scale portion is fixed to the center of the base.

[0010] In some embodiments of the present invention, the base is a circular plate made of stainless steel.

[0011] In some embodiments of the present invention, the central scale portion is a cylindrical rod made of stainless steel.

[0012] In some embodiments of the present invention, the clamping bar is a stainless steel clamping bar.

[0013] In some embodiments of the present invention, the ring is made of polypropylene.

[0014] On the other hand, the utility model also provides an adjustment component, including the small bioreactor blade angle adjuster described in the first aspect of the utility model, the small bioreactor blade angle adjuster includes a central scale portion and also includes a stirring paddle, the stirring paddle includes a paddle shaft and a plurality of blades, each of the blades is movably connected to the paddle shaft, and the paddle shaft is sleeved on the central scale portion.

[0015] In some embodiments of the present invention, a plurality of blade screws are further provided on the propeller shaft for fixing the propeller shaft and the propeller blades.

[0016] In some embodiments of the present invention, the angle between the blade surface of the blade and the bottom surface of the base is 0 to 90°.

[0017] Compared with the prior art, the beneficial effects of the utility model are:

[0018] The utility model sets the stirring blade on the central scale part, moves the limit caliper assembly according to the required blade angle, limits the blade height, and thus achieves the purpose of adjusting the blade angle. The utility model has a simple structure and is easy to operate, and can adjust any required angle of 0 to 90 degrees. It is used as an adjustment tool without other supporting facilities. It has strong versatility, high precision, and is easy to use for adjusting the blade angle of a small bioreactor. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 Shown is a three-dimensional structural schematic diagram of a blade angle regulator for a small bioreactor of the utility model.

[0020] Figure 2 It shows a schematic diagram of the structure of the small bioreactor blade angle adjuster of the utility model installed in conjunction with the stirring paddle.

[0021] Figure 3It shows a schematic diagram of the structure of the blade angle adjuster of the small bioreactor of the utility model in cooperation with the blade limiter in the stirring paddle.

[0022] Figure 4 Shown is a schematic structural diagram of the adjusted stirring paddle of the utility model.

[0023] Figure 5 Shown is a schematic structural diagram of the adjustment component of the utility model.

[0024] Component number description:

[0025] 1 Small bioreactor blade angle adjuster

[0026] 11. Base

[0027] 12 Center scale

[0028] 121 scale ruler

[0029] 13 Limit caliper assembly

[0030] 131 Ring

[0031] 132 Card Strip

[0032] 2 stirring paddle

[0033] 21 propeller shaft

[0034] 22 blades

[0035] 23 Propeller screw DETAILED DESCRIPTION

[0036] The following is a further detailed description of the specific implementations of the present invention in conjunction with the accompanying drawings. These implementations are only used to illustrate the present invention, but not to limit the present invention.

[0037] The terms "center", "longitudinal", "lateral", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0038] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0039] In addition, in the description of the present invention, unless otherwise specified, “plurality” means two or more.

[0040] refer to Figures 1 to 5 The embodiment of the utility model provides a small bioreactor blade angle regulator. Figure 1 The small bioreactor blade angle adjuster includes a base 11, on which a central scale portion 12 is provided, and the central scale portion 12 is perpendicular to the base 11, and also includes a limit caliper assembly 13, the limit caliper assembly 13 includes a ring 131 and a clamping strip 132 arranged along the diameter direction of the ring 131, the ring 131 is arranged parallel to the base 11, and the bottom surface of the base 11 and the ring 131 of the limit caliper assembly 13 are in parallel horizontal planes to ensure the level of the blade 22. The clamping strip 132 is connected to the central scale portion 12, and the clamping strip 132 can slide back and forth in the height direction relative to the central scale portion 12, and is suitable for making the ring 131 contact the blade 22 and limit the height of the blade 22 by sliding the clamping strip 132, so as to achieve the purpose of adjusting the angle of the blade 22 (such as Figure 5 It should be noted that, in order to illustrate the matching relationship between the clamping strip 132 and the ring 131 in the limit caliper assembly 13 and the blade 22, the blade 22 is introduced here, but the blade 22 is not a part of the small bioreactor blade angle regulator, nor is it a protective component in the small bioreactor blade angle regulator.

[0041] In the small bioreactor blade angle regulator provided by the embodiment of the utility model, Figure 1 The central scale portion 12 is provided with a scale 121 .

[0042] In the small bioreactor blade angle regulator provided by the embodiment of the utility model, the scale size of the scale ruler 121 gradually increases from the end close to the base 11 toward the top of the central scale part 12.

[0043] In the small bioreactor blade angle adjuster provided by the embodiment of the utility model, in one embodiment, a slide rail is extended along the height direction on the central scale part 12, and the clamping strip 132 can slide along the slide rail. The size of the clamping strip 132 is equal to the size of the slide rail. In this way, the clamping strip 132 can be in precise contact with the central scale part 12, can slide up and down, indicate the height of the clamping strip 132, and will not be too loose and fall off freely.

[0044] In the small bioreactor blade angle regulator provided by the embodiment of the utility model, Figure 1 The bottom end of the central scale portion 12 is fixed to the center of the base 11 .

[0045] In the small bioreactor blade angle regulator provided by the embodiment of the utility model, the base 11 is a circular plate made of stainless steel. The central scale portion 12 is a cylindrical rod made of stainless steel. The clamping strip 132 is a stainless steel clamping strip. The material of the ring 131 is polypropylene (PP).

[0046] The embodiment of the present invention also provides an adjustment component, such as Figure 2 , 3 5, including the aforementioned small-scale bioreactor blade angle adjuster 1, the small-scale bioreactor blade angle adjuster 1 includes a central scale portion 12, and also includes a stirring paddle 2, the stirring paddle 2 includes a paddle shaft 21 and a plurality of paddle blades 22, each of the paddle blades 22 is movably connected to the paddle shaft 21, and the paddle shaft 21 is sleeved on the central scale portion 12.

[0047] In the adjustment component provided in the embodiment of the utility model, Figure 3 , 4 The propeller shaft 21 is also provided with a plurality of propeller screws 23 for fixing the propeller shaft 21 to the propeller blades 22. For example, the propeller blades 22 are respectively connected to the propeller shaft 21 for rotation, and the propeller shaft 21 and the propeller blades 22 are fixed by the propeller screws 23 after being rotated to a suitable angle.

[0048] In the adjustment assembly provided in the embodiment of the utility model, the angle between the blade surface of the blade 22 and the bottom surface of the base 11 is 0-90°.

[0049] The working principle of this utility model:

[0050] The small bioreactor blade angle regulator adopts the principle of trigonometric function, and calculates the height by knowing the right triangle angle and the length of the hypotenuse (blade 22). The blade 22 is limited by the small bioreactor blade angle regulator to achieve the purpose of angle regulation.

[0051] The specific usage process is as follows:

[0052] 1. First measure the length of the blade 22, and then put the blade shaft 21 of the stirring blade 2 on the central scale part 12 of the small bioreactor angle adjuster. Figure 2 shown.

[0053] 2. Calculate the height between the limit caliper assembly 13 and the base 11, and slide the limit caliper assembly 13 to this height.

[0054] like Figure 5 For example, if the length of the blade 22 is 30 mm and the angle of the blade 22 needs to be adjusted to 45°, the height h between the limit caliper assembly 13 and the base 11 is calculated according to the trigonometric function:

[0055] h=sin45°×30mm

[0056]

[0057] 3. Adjust the blade 22 so that its top and bottom are parallel to the bottom surface of the base 11 and the ring 131 of the limit caliper assembly 13, respectively. The blade 22 rotates relative to the propeller shaft 21, and the propeller shaft 21 and the blade 22 are fixed with the blade screw 23. Figure 3 shown.

[0058] 4. Take out the limit caliper assembly 13, take out the stirring paddle 2, and the angle adjustment of the paddle 22 is completed. Figure 4 shown.

[0059] In summary, the small bioreactor blade angle regulator and the regulating assembly of the utility model have a simple structure, are easy to operate, and can adjust any required angle of 0 to 90 degrees. It is used as an adjustment tool without other supporting facilities. The adjustment of the blade angle of the small bioreactor is highly versatile, high in precision, and easy to use.

[0060] In summary, the utility model effectively overcomes various shortcomings of the prior art and has high industrial utilization value.

[0061] The above embodiments are merely illustrative of the principles and effects of the present invention, and are not intended to limit the present invention. Anyone familiar with the technology may modify or alter the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or alterations made by a person of ordinary skill in the art without departing from the spirit and technical concept disclosed in the present invention shall still be covered by the claims of the present invention.

Claims

1. A small bioreactor blade angle adjuster, characterized in that: The invention comprises a base (11), wherein a central scale portion (12) is provided on the base (11), wherein the central scale portion (12) is perpendicular to the base (11), and further comprises a limit caliper assembly (13), wherein the limit caliper assembly (13) comprises a circular ring (131) and a clamping strip (132) arranged along the diameter direction of the circular ring (131), wherein the circular ring (131) is arranged parallel to the base (11), and the clamping strip (132) is connected to the central scale portion (12), and the clamping strip (132) can slide back and forth in a height direction relative to the central scale portion (12), and is suitable for adjusting the angle of the blade (22) by sliding the clamping strip (132) so that the circular ring (131) contacts the blade (22) and limits the height of the blade (22).

2. The small bioreactor blade angle adjuster according to claim 1, characterized in that: The central scale portion (12) is provided with a scale (121).

3. The small bioreactor blade angle adjuster according to claim 2, characterized in that: The scale size of the scale ruler (121) gradually increases from the end close to the base (11) toward the top of the central scale part (12).

4. The small bioreactor blade angle adjuster according to claim 1, characterized in that: A slide rail is provided on the central scale portion (12) extending in the height direction, and the clamping strip (132) can slide along the slide rail.

5. The small bioreactor blade angle adjuster according to claim 4, characterized in that: The size of the clamping strip (132) is equal to the size of the slide rail.

6. The small bioreactor blade angle adjuster according to claim 1, characterized in that: The bottom end of the central scale portion (12) is fixed to the center of the base (11).

7. The small bioreactor blade angle regulator according to claim 1, characterized in that: The base (11) is a circular plate made of stainless steel; And / or, the central scale portion is a cylindrical rod made of stainless steel; And / or, the clamping strip (132) is a stainless steel clamping strip; And / or, the material of the ring (131) is polypropylene.

8. An adjustment component, characterized in that: It comprises a small bioreactor blade angle regulator (1) as described in any one of claims 1 to 7, wherein the small bioreactor blade angle regulator (1) comprises a central scale portion (12), and also comprises a stirring paddle (2), wherein the stirring paddle (2) comprises a paddle shaft (21) and a plurality of paddle blades (22), wherein each of the paddle blades (22) is movably connected to the paddle shaft (21), and the paddle shaft (21) is sleeved on the central scale portion (12).

9. The adjustment assembly according to claim 8, characterized in that The propeller shaft (21) is also provided with a plurality of propeller blade screws (23) for fixing the propeller shaft (21) and the propeller blades (22) in connection.

10. The adjustment assembly according to claim 8, characterized in that The angle between the blade surface of the blade (22) and the bottom surface of the base (11) is 0 to 90 degrees.

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