30 results about "Usnic acid" patented technology

The invention relates to a Chinese herbal medicinal bactericide, which aims to solve the problem of public hazards of the conventional bactericide. The bactericide comprises the following Chinese herbal medicines in part by weight: 40 to 120 parts of sessile stemona root, 40 to 120 parts of camphor tree, 35 to 105 parts of pomegranate rind, 35 to 105 parts of macleaya cordata, 35 to 105 parts of common andrographis herb, 35 to 105 parts of isatis root, 30 to 90 parts of barberry root, 30 to 90 parts of vietnamese sophora root, 30 to 90 parts of common fibraurea stem, 30 to 90 parts of densefruit pittany root-bark, 30 to 90 parts of officinal magnolia bark, 30 to 90 parts of common threewingnut root, 25 to 75 parts of akebia stem, 25 to 75 parts of oriental variegated coralbean bark, 25 to75 parts of fourstamen stephania root and 25 to 75 parts of humifuse euphorbia herb. The bactericide is prepared by the following steps of: performing ethanol precipitation on the Chinese herbal medicines to obtain the original liquid medicine; diluting sodium usnic acid by using a solvent; and adding 0.1 to 0.3 weight percent of diluted sodium usnic acid into the original liquid medicine. The finished Chinese herbal medicinal bactericide comprises 0.3 percent of stemonine, is brownish red, has the pH value of 7 to 8 and the density of 1.10g / cm<3>, and has the advantages of capability of effective sterilization and no damage to humans.

The invention relates to a Chinese herbal medicinal insecticide, and aims to solve the problem of public hazards of the conventional insecticide. The Chinese herbal medicinal insecticide comprises the following Chinese herbal medicines in part by weight: 50 to 110 parts of macleaya cordata, 50 to 110 parts of eucalyptus robusta smith, 40 to 100 parts of betel nut, 40 to 100 parts of pumpkin seed,40 to 100 parts of clematis root, 40 to 100 parts of celastrus angulatus, 30 to 90 parts of stone-like omphalia, 30 to 90 parts of grand torreya seed, 30 to 90 parts of camphor tree, 30 to 90 parts of pomegranate rind, 30 to 90 parts of lightyellow sophora root, 30 to 90 parts of rhododendron molle, 30 to 70 parts of fourstamen stephania root, 30 to 70 parts of sessile stemona root, 30 to 70 parts of hindu datura flower and 30 to 70 parts of liquoric root. The Chinese herbal medicinal insecticide is prepared by the following steps of: performing alcohol precipitation on the Chinese herbal medicines to obtain the original liquid medicine; diluting sodium usnic acid by using a solvent; and adding 0.1 to 0.3 weight percent of diluted sodium usnic acid into the original liquid medicine. The finished Chinese herbal medicinal insecticide comprises 0.5 percent (g / ml) of sanguinarine, is brownish red, has the ph value of 7 to 8 and the density of 1.10g / cm<3>, and has the advantages of effective insecticidal capability, no damage to humans, high adsorbability and durable seepage force.

The invention relates to a Chinese herb biological disinfectant to solve the public nuisance problem of the traditional disinfectant. The Chinese herb biological disinfectant is prepared by adopting the steps of preparing primary liquid medicine by ethanol precipitation of the following bulk drugs in weight ratio: common andrographis herb 40-120, santonin 40-120, celastrus angulatus 35-105, camphor tree 35-105, stephania tetrandra 35-105, rhododendron molle 35-105, macleaya cordata 30-90, pomegranate rind 30-90, clematis root 30-90, radix stemonae 30-90, eucalyptus robusta 30-90, sophora flavescens 30-90, cortex dictamni 25-75, Chinaberry bark and root-bark 25-75, rhizoma corydalis 25-75 and liquorice root 25-75; and adding sodium usnic acid with weight ratio of 0.01-0.03% in the primary liquid medicine, wherein the sodium usnic acid is dissolved with a solvent before the sodium usnic acid is added in the primary liquid medicine. The Chinese herb biological disinfectant contains 0.2% andrographolide, with color being brownish red, ph being 7-8 and density being 1.10g / cm<3>. The Chinese herb biological disinfectant has the advantages of effective disinfection and no harm to human.

The invention discloses a non-woven fabric for a vehicle cushion, and relates to the technical field of non-woven fabric manufacturing. The problem that an existing non-woven fabric for the vehicle cushion is poor in mechanical property is mainly solved. The non-woven fabric is prepared from modified polypropylene fiber, acrylic acid modified corn bran fiber, bamboo carbon fiber, modified talcum powder, mugwort extracts, a nano-silver solution, carboxymethyl cellulose, polylactic acid, usnic acid, a softening agent, an antistatic agent and a lubricating agent. Accordingly, maleic anhydride, beta-cyclodextrin and chitosan are utilized for together modifying polypropylene fiber, by means of the conditions of high temperature, irradiation and the like, the mechanical property of the fiber canbe well improved, and the flexibility is enhanced; by means of the synergistic effect of the mugwort extracts and the nano-silver solution, the antibacterial property of the prepared non-woven fabricis effectively improved, the antibacterial effect is enhanced; by adding polylactic acid and usnic acid, the antibacterial property, fire resistance and ultraviolet resistance of the prepared non-woven fabric are further improved.

An ultrasonic technology for extracting general flavone from pine needles includes such steps as drying, washing with drinking water, drying, immersing in alcohol solution, ultrasonic processing, collecting the liquid extract, extracting respectively by petroether and ethyl acetate, collecting extracted liquid, concentrating and vacuum freeze-drying. It has high output rate of usnic acid.

The invention relates to a natural air freshener which mainly consists of natural bacteriostatic active substances and a natural emulsifier and has a sterilizing function. The air freshener is prepared from the following components in percentage by weight: 1-3% of zanthoxylum oil, 0.5-2% of clove essential oil, 0.5-2% of litsea cubeba oil, 0.5-1% of oregano essential oil, 0.5-1% of usnic acid, 0.01-0.2% of tremella polysaccharide, 3-5% of one or more of tea saponin or soapberry saponin or saponin and 85.80-93.99% of de-ionized water. By emulsifying and dispersing essential oil ingredients by virtue of the natural emulsifier, the natural air freshener disclosed by the invention, different from conventional alcohol solvent products, is safe and not stimulating; meanwhile, with the significant bacteriostatic activity, the natural air freshener can be used for effectively inhibiting the growth of planktonic microorganisms in public places (railway station, movie theater and the like), hotels, rooms, cars and the like, and can be used for freshening the air and removing odor.

The invention discloses a method for extracting volatile oil from usnea and simultaneously extracting usnea polysaccharide and usnic acid. The method for extracting volatile oil from usnea includes the following steps: (1) reflux extraction: crushing dried usnea, adding an organic solvent, reflux extracting, and filtering to obtain an extracting solution; (2) column chromatography separation: arranging a chromatography column filled with a filler on the extracting solution obtained in the step (1), collecting an effluent liquid, and concentrating to obtain the volatile oil. The invention further discloses a method for simultaneously extracting usnea polysaccharide and usnea acid. In the volatile oil, usnea polysaccharide and usnea acid products obtained by the method, the mass content of the volatile oil, usnea polysaccharide and usnea acid can reach 95.2%, 97.5% and 99.7% respectively, and the yield can reach 95%, 95% and 97% respectively. The method can comprehensively utilize usnearesources, has high product yield, high purity, simple process, strong operability, low cost and little pollution, so that the method is suitable for industrial production.

The invention relates to medicinal liquid with bacteriostatic and disinfectant effect and application thereof. The medicinal liquid comprises active ingredients including, by weight, 8-12 parts of Cortex magnoliae officinalis, 12-18 parts of Fructus cnidii volatile oil, 10-15 parts of senecio alcohol extract and 6-10 parts of usnic acid. The active ingredients are all natural extract, so that the medicinal liquid is high in biodegradability and free of environment pollution; the medicinal liquid is mild in property, free of damage to skin and free of irritation and has ideal bacteriostatic, disinfectant and anti-inflammatory effect. The medicinal liquid has wide application prospect in hygiene products, and presents ideal ideal bacteriostatic, disinfectant and anti-inflammatory effect especially in application of urination tissues (wet tissues and dry tissues).

The invention relates to the technical field of medicines, in particular to a composition and application thereof. The composition is prepared from the following substances in parts by mass: 3 to 6 parts of usnic acid, 3 to 10 parts of sophocarpidine, 5 to 10 parts of herba houttuyniae extract, 5 to 10 parts of motherwort herb extract, 8 to 15 parts of iodine-chitosan, 5 to 15 parts of cortex phellodendri extract, 30 to 50 parts of purified water, and 1 to 3 parts of a1-15c bio-compound enzyme. The composition is moderate without stimulation, and can be used for quickly clearing pelvic effusion and junks in a uterine cavity.

The invention relates to sterilizing and skin-care liquid soap, which is prepared from the following components in parts by weight: 40 to 48 parts of lauramidepropyl amine oxide, 4 to 5 parts of chondroitin sulfate, 20 to 30 parts of medical stone powder, 900 to 1200 parts of deionized water, 120 to 150 parts of sodium lauryl ether sulfate, 60 to 70 parts of sodium cocoyl glycinate, 20 to 30 parts of clove oil, 10 to 12 parts of usnic acid, 16 to 18 parts of folium sennae extract, 0.4 to 0.6 part of distannous citrate, 0.4 to 0.6 part of sodium lactate, and 8 to 12 parts of sodium chloride. The sterilizing and skin-care liquid soap is prepared by compounding multiple plant essence and natural skin-care components, as well as a surfactant by a special method, and the components have an outstanding synergistic effect with one another; the liquid soap has good anti-bacteria and sterilizing effect, and by comparison with general pure chemical liquid soap, the sterilizing and skin-care liquid soap has small irritation to the skin, and has the effect of moisturizing the skin and preserving moisture.

The invention discloses a medical plant-substrate-based lubricant, which is prepared from the following components in parts by weight: 2 to 4 parts of usnic acid, 2 to 4 parts of eugenol type basil oil, 2 to 4 parts of rosemary essential oil, 15 to 22 parts of Chinese gall extract, 1 to 2 parts of hydroxypropyl methyl cellulose, 1 to 1.5 parts of kaempferol 3-glucoside, 5 to 7 parts of palmitic acid, 0.5 to 1 part of tropicamide, 3 to 5 parts of chitosan, 3 to 5 parts of polyalkylene glycol, 12 to 16 parts of typha orientalis presl extract, 32 to 38 parts of glycerin and 600 to 650 parts of de-ionized water. The lubricant is very high in lubricity, low in viscosity and harmless to a body cavity; most of the components are plant raw materials, and can be automatically degraded into water and low molecular compounds in a human body to be metabolized from the human body, so that the lubricant is very safe and environment-friendly; moreover, the lubricant is slightly aromatic, and has good anesthetic and bactericidal effects.

The invention discloses a medical anti-HPV dressing and a preparation method thereof. The medical anti-HPV dressing comprises the following materials in parts by weight: 5 to 6 parts of a sinopodophyllum hexandrum extract, 2 to 5 parts of indigo naturalis powder, 5 to 10 parts of rhizoma scirpi, 3 to 10 parts of rhizoma curcumae, 2 to 3 parts of tea plant oil, 1 to 1.5 parts of gallnut, 8 to 10 parts of semen coicis, 6 to 8 parts of prunella spike, 6 to 8 parts of field pennycress, 6 to 8 parts of seeds of garden balsam, 8 to 10 parts of moutan bark, 1 to 1.3 parts of radix sophorae subprostratae, 1 to 1.2 parts of sophocarpidine, 1 to 1.3 parts of bletilla striata, 2 to 3 parts of seabuckthorn seed oil, 2 to 5 parts of spina gleditsiae, 6 to 8 parts of almonds, 2 to 2.5 parts of astaxanthin, 1 to 1.3 parts of flowers of radix euphorbiae lantu, 1.2 to 1.3 parts of edible tulip, 1 to 1.3 parts of eupolyphaga seu steleophaga, 3 to 6 parts of Qinling usnic acid, and 2 to 2.5 parts chitosan oligosaccharide; and the medical anti-HPV dressing has the advantages of preventing and removing cervical epithelial cell virus, conditioning cervical erosion abnormalities with different degrees, removing the smell, balancing secretion of the reproductive system, compacting and retracting the pudendum, and restoring elasticity of the pudendum.

The invention discloses dry powder for preventing and treating the saprolegniasis of an aquatic animal. The dry powder is prepared from the following components in percentage by weight: 28 to 36 percent of usnic acid-acetone solution, 15 to 25 percent of Chinese herbal medicinal liquid medicine, 10 to 20 percent of sulfosalicylic acid, 30 to 40 percent of diatomite and 1 to 3 percent of bacillus.A single-variety medicament, a traditional Chinese medicine, a microbe and an auxiliary material in the prior art are utilized by the dry powder and the dry powder for preventing and treating the saprolegniasis of the aquatic animal is provided, has the advantages of simple formula, low cost, convenient use, safety and high efficiency and is used for realizing prevention and treatment effects on the saprolegniasis, occurring during aquaculture, of the aquatic animal.

Zinc:usnic acid complexes having a 1:2 zinc to usnate molar ratio and methods of preparing them. Oral care compositions comprise the Zn:usnate complexes may be useful to improve oral health.

The invention belongs to the technical field of veterinary drugs, and provides application of usnic acid in preparation of a medicine for preventing and treating porcine epidemic diarrhea. Usnic acid plays a role in resisting PEDV (porcine epidemic diarrhea virus) in a dose-dependent manner, and has an obvious inhibition effect on different strains of PEDV, and the antiviral effect of usnic acid mainly plays a role in a virus replication stage. Research finds that PEDV infection can promote cell autophagy, autophagy has a promoting effect on virus replication, usnic acid can inhibit Vero cell autophagy, and through the effects of an autophagy accelerant 3-MA and an inhibitor rapamycin, usnic acid can play a role in resisting PEDV by inhibiting the autophagy process of cells. The invention discloses the inhibition effect and possible inhibition mechanism of usnic acid on PEDV for the first time, and provides a new alternative drug for prevention and treatment of PEDV.

The invention discloses usnic acid derivatives as well as a preparation method and application thereof in preparation of anti-senile dementia drugs. It is reported for the first time that the usnic acid derivatives have acetylcholin esterase inhibition activity. The structural formulas of the usnic acid derivatives (compounds 1-4) are shown as formulas 1-4. The compounds 1-4 have relatively good activity of inhibiting acetylcholin esterase; IC50s of the compounds are 51.0 + / -9.3 mu M, 50.0 + / -2.1 mu M, 50.0 + / -8.6 mu M and 75.0 + / -1.3 mu M respectively, and the compounds can be used for preparing acetylcholin esterase inhibition drug lead compounds in the later period through structural modification optimization. Therefore, the usnic acid derivatives derived from deep sea fungi have the clinical application potential of preventing and treating senile dementia.

The invention relates to an antibacterial Chinese herbal medicine liquid for spray-coating wounds. The antibacterial Chinese herbal medicine liquid solves the problem that the existing disinfectant has high irritation. Extract of Chinese herbal medicines as raw materials subjected to alcohol precipitation is added with purified water having the weight 7-11 times that of the extract so that a water-soluble raw medicine is obtained, and the water-soluble raw medicine is added with usnic acid sodium salt so that the desired product is obtained; or the extract of the Chinese herbal medicines as raw materials subjected to alcohol precipitation is added with a part of purified water so that a water-soluble raw medicine is obtained and then an usnic acid sodium salt aqueous solution prepared from usnic acid sodium salt and the other part of the purified water is added into the water-soluble raw medicine so that the desired product is obtained, wherein a weight ratio of the extract subjected to alcohol precipitation to the two parts of purified water is 1: 7-11 and a weight ratio of usnic acid sodium salt to the water-soluble raw medicine is 1.5-3: 1000. The Chinese herbal medicines as raw materials comprises, by weight, 50-110 parts of common andrographis herb, 50-110 parts of cortex phellodendri, 40-100 parts of radix berberidis, 40-100 parts of Celastrus angulatus, 40-100 parts of isatis root, 40-100 parts of radix sophorae flavescentis, 40-80 parts of mulberry bark, 40-80 parts of santonin, 40-80 parts of aloe, 40-80 parts of fructus rosae laevigatae, 40-80 parts of akebia stem, 40-80 parts of subprostrate sophora, 30-70 parts of Sichuan red orange peel, 30-70 parts of rheum officinale, 30-70 parts of corydalis tuber and 30-70 parts of licorice root. The antibacterial Chinese herbal medicine liquid has the advantages of small irritation, lasting disinfection effect, short treatment course and use convenience.

The invention relates to a Chinese herbal medicinal insecticide, and aims to solve the problem of public hazards of the conventional insecticide. The Chinese herbal medicinal insecticide comprises the following Chinese herbal medicines in part by weight: 50 to 110 parts of macleaya cordata, 50 to 110 parts of eucalyptus robusta smith, 40 to 100 parts of betel nut, 40 to 100 parts of pumpkin seed, 40 to 100 parts of clematis root, 40 to 100 parts of celastrus angulatus, 30 to 90 parts of stone-like omphalia, 30 to 90 parts of grand torreya seed, 30 to 90 parts of camphor tree, 30 to 90 parts of pomegranate rind, 30 to 90 parts of lightyellow sophora root, 30 to 90 parts of rhododendron molle, 30 to 70 parts of fourstamen stephania root, 30 to 70 parts of sessile stemona root, 30 to 70 parts of hindu datura flower and 30 to 70 parts of liquoric root. The Chinese herbal medicinal insecticide is prepared by the following steps of: performing alcohol precipitation on the Chinese herbal medicines to obtain the original liquid medicine; diluting sodium usnic acid by using a solvent; and adding 0.1 to 0.3 weight percent of diluted sodium usnic acid into the original liquid medicine. The finished Chinese herbal medicinal insecticide comprises 0.5 percent (g / ml) of sanguinarine, is brownish red, has the pH value of 7 to 8 and the density of 1.10g / cm<3>, and has the advantages of effective insecticidal capability, no damage to humans, high adsorbability and durable seepage force.

The present invention relates to an usnic acid photodegradation product and an application thereof in preparation of drugs, cosmetics or health-care products resistant to ultraviolet radiation. Lightenergy is used to accelerate degradation of usnic acid and 5 compounds, including 2 new compounds and 3 known compounds are successfully isolated and purified. Subsequently, human normal hepatocytes,human epidermal melanocytes and human epidermal keratinocytes are used as main experiment subjects to evaluate effects of the usnic acid and degradation products thereof on cell viability and protection against ultraviolet irradiation. Results show that cytotoxicity of the degradation products is lower than that of the usnic acid, the usic acid and the degradation products thereof have the ultraviolet radiation protection effects on the above types of cells, and some of the usnic acid photodegradation products have stronger protection effect against the ultraviolet radiation for cells than theusnic acid.

The invention discloses a production technology for extracting usnic acid from usnea longissima. The technology comprises the steps that a raw material is subjected to coarse grinding, and fed in from a feeding hopper; an extraction tank unit host rotates to slowly push the material from the front end of a unit backwards; an extraction solvent enters an extraction tank from a liquid inlet tube at the tail end of the unit, passes through the moving material from the back end of the tank, and flows towards the front end; and solid and liquid substances are contacted fully in an inverse motion, so that effective components in the medicinal material are extracted. Dregs are forcibly pushed to a dreg discharge port by a discharge transport and then discharged; a special juice squeezer squeezes the dregs; residual medicine liquor in the dregs is squeezed out of a medicinal material tissue; and the content of the residual medicine liquor in the dregs is reduced. The extraction efficiency is higher, and the extraction is more complete. The method adopts a continuous extraction tank unit for extraction, and is combined with a silica gel column chromatography for purification, so that a separating effect is better. Finished usnic acid with a maximum yield of 1% and the content above 95% can be obtained.

The invention discloses shaddock peel containing weight loss biscuits. The shaddock peel containing weight loss biscuits are mainly prepared from, by weight, 100 parts of flour, 6 parts of flos chrysanthemi, 12 parts of shaddock peels, 18 parts of pericarpium citri reticulatae, 9 parts of fructus crataegi, 14 parts of egg white, 5 parts of salad oil, 0.05 part of vitamins, 0.01 part of usnic acid, 0.02 part of naringin, 0.03 part of artesunate, 0.5 part of granulated sugar and 0.1 part of salt. The shaddock peel containing weight loss biscuits are low in sugar content, crispy and tasty and are capable of effectively replenishing human body energy without increasing blood sugar excessively, and high nutritional healthcare value is achieved; the problem of functional singleness of existing biscuits is solved, weight loss and lipid reduction can be realized in eating of the biscuits, and the shaddock peel containing weight loss biscuits are suitable for people requiring weight loss or high in blood lipid.

The invention discloses a biological composite enzyme composition lotion and applications thereof. The lotion comprises a cleaning itch-relieving external lotion and a drug-application anti-inflammation external lotion. The cleaning itch-relieving external lotion comprises the following components in parts by weight: 0.5 to 1.5 parts of mint, 0.5 to 1.5 parts of usnic acid, 0.1 to 0.5 part of dibutyl hydroxyl toluene, and 3 to 6 parts of saponin; and the drug-application anti-inflammation external lotion comprises the following components in parts by weight: 0.5 to 1.5 parts of plantamajoside, 0.5 to 1.5 parts of isopimpinellin, 0.1 to 0.5 part of resveratrol, 0.5 to 1.5 parts of luteolin, 1 to 3 parts of matrine, 1 to 5 parts of guar gum, 0.3 to 3.0 parts of tea polyphenol, 1 to 5 parts of alpha1-15c biological composite enzyme, and 10 to 30 parts of glycerin. The lotion can be rapidly applied to the affected parts of a patient, is very convenient and effective, barely influences the daily life and work of the patient, and rapidly relieves the uncomfortable feeling.