The invention provides a slow-sinking type feed for treating septicaemia of axolotl and a preparation method of the slow-sinking type feed, and relates to the technical field of feeds. The slow-sinking type feed comprises the following components in parts by weight: 10-30 parts of high gluten flour, 20-40 parts of soybean meal, 50-100 parts of fish meal, 40-60 parts of krill powder, 5-20 parts ofblack tea powder, 20-40 parts of spirulina, 35-50 parts of fish oil, 1-10 parts of turmbicula akamushi powder, 1-10 parts of a vitamin premix, 1-3 parts of metronidazole, 1-2 parts of hydroxypropyl methylcellulose, 5-10 parts of herba artemisiae scopariae, 5-10 parts of radix scutellariae, 5-10 parts of Chinese magnoliavine fruits, 2-6 parts of honeysuckle flowers, 1-4 parts of coix seeds, 3-7 parts of amomum cardamomum, 1-3 parts of fructus gardeniae, 1-3 parts of costus roots, 1-3 parts of radix lithospermi, 2-4 parts of radix sophorae flavescentis and 10-15 parts of radix angelicae dahuricae. The slow-sinking type feed has good prevention and treatment effects on the septicaemia and saprolegniasis; and the survival rate and the growth speed of the axolotl after eating the feed disclosedby the invention are greatly increased.