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2results about How to "Improve customization ability" patented technology

A lectin affinity-based flow analysis method for serum glycosylation

The present application belongs to the technical field of glycosylation detection and analysis, and particularly relates to a serum glycosylation flow analysis method based on lectin affinity. The present application enriches target molecules in a sample to be measured by coupling a polystyrene microsphere with a decoy molecule, and then incubates the polystyrene microsphere with a fluorescently labeled lectin, and directly analyzes the glycosylation information of the target molecules by a flow cytometer. In the present application, the decoy molecule of the target protein is coupled to the polystyrene microsphere to enrich the target protein, and the target protein is focused for subsequent analysis, which can effectively reduce the field of view and improve the specificity. After the lectin is combined with the target protein, the fluorescence analysis of the flow cytometry is directly performed, which can effectively reduce the damage of the washing operation to the affinity of the lectin, and thus overcomes the weakness of the weak affinity between the lectin and the sugar chain. Moreover, only a small amount of sample is required to realize the analysis of multiple lectins, and the washing-free real-time analysis can be realized, which provides a new way for the analysis of glycosylation by using lectin, and has important potential application value.
Owner:THE SIXTH AFFILIATED HOSPITAL OF SUN YAT SEN UNIV

Semiconductor testing apparatus

PendingCN122283381AImprove customization abilityHemt circuitsElectrical connection
This application relates to a semiconductor testing apparatus. The tester includes: a performance board unit for mounting a device under test (DUT) for testing a semiconductor circuit; a plurality of substrate units electrically connected to the DUT via the performance board unit; and a main body unit having a receiving portion for accommodating the plurality of substrate units, wherein the performance board units are detachably mounted to the main body unit with the opening of the receiving portion closed.
Owner:NIHON MICRONICS KK