11results about How to "Reduce obesity" patented technology

The invention provides an application of lactobacillus rhamnosus NKU FL1-8 in resisting obesity, serum inflammation and cognitive impairment caused by high fat diet, and belongs to the technical field of microorganisms. The lactobacillus rhamnosus NKU FL1-8 has the advantages that the lactobacillus rhamnosus NKU FL1-8 can be used for resisting the obesity, the serum inflammation and the cognitive impairment caused by high fat diet; the invention finds that the lactobacillus rhamnosus NKU FL1-8 can obviously reduce adipose tissue increase caused by high-fat diet, relieve liver function impairment caused by high-fat diet, inhibit serum inflammation caused by high-fat diet, improve cognitive impairment caused by high-fat diet, strengthen intestinal barrier, increase the content of short-chain fatty acid in cecum and excrement and improve the immunity of the cecum. The intestinal flora is regulated, and the diversity of the intestinal flora is improved, so that related diseases caused by high-fat diet are effectively resisted.

The present application provides a novel phenyl derivative, 5-[(2,4-dinitrophenoxy)methyl]-1-methyl-2-nitro-1H-imidazole or a pharmaceutically acceptable salt thereof, which is useful for regulating mitochondria activity, reducing adiposity, treating diseases including diabetes and diabetes-associated complications.

The present invention provides a method for planting cauliflower on a coastal tidal flat with high salt content, and the method for planting cauliflower on a coastal tidal flat with high salt content comprises the following steps: (1) cultivating seedlings: preparing a seedling culture medium and cultivating cauliflower seedlings; (2) leveling the land: turning the soil of the field and applying compound fertilizer; (3) transplanting seedlings: transplanting the obtained cauliflower seedlings to the field and watering and irrigating; (4) field management: applying a crop salt-resistance agent to the cauliflower, and performing weeding and pest control; (5) picking the cauliflower: picking by staged harvesting, and applying a crop salt-resistance agent after each harvest. The planting process of the method for planting cauliflower on a coastal tidal flat with high salt content of the present invention is simple and convenient, the cauliflower grows fast, has a long picking cycle and high yield. The planting method provided by the present invention can fully and effectively utilize the coastal tidal flat, improve the soil of the coastal tidal flat, and improve the economic benefits of cauliflower planting.

The invention discloses medicinal and edible meal replacement powder with an effect of relieving liver injury / inflammation as well as a preparation method and application of the medicinal and edible meal replacement powder. The formula of the medicinal and edible meal replacement powder comprises the following components in parts by weight: 20-30 parts of mulberries, 20-30 parts of cooked small red beans, 15-25 parts of cooked Chinese yams, 5-15 parts of black sesames, 5-15 parts of cooked brown rice and 5-15 parts of walnut kernels. The medicinal and edible meal replacement powder disclosed by the invention has the functions of regulating fat cell factors, relieving lipid metabolism disorder, improving liver injury caused by high fat diet and regulating and controlling inflammatory response of a body.

The invention belongs to the technical field of microorganisms and metagens, and discloses a pediococcus acidilactici LTJ51 with lipid-lowering and weight-losing capacity, a metagen of the pediococcus acidilactici LTJ51 and application of the pediococcus acidilactici LTJ51, the name of the pediococcus acidilactici LTJ51 is LTJ51, the classification name of the pediococcus acidilactici LTJ51 is pediococcus acidilactici, the preservation number of the pediococcus acidilactici LTJ51 is CGMCC No.31545, the preservation date of the pediococcus acidilactici LTJ51 is August 5, 2024, and the preservation number of the pediococcus acidilactici LTJ51 is CGMCC No.31545. The strain is preserved in China General Microbiological Culture Collection Center (CGMCC), No. 3, No.1 Yard, Beichen West Road, Chaoyang District, Beijing. The pediococcus acidilactici disclosed by the invention is derived from fermented grains in the fermentation process of traditional fermented food white spirit, belongs to a strain pediococcus acidilactici LTJ51 which is recognized to be safe and can be used for food, and is safe in source and free of pathogenicity. The pediococcus acidilactici has the effect of relieving, improving or treating the HFD-induced obesity.

The invention discloses a composition with lipid-lowering and weight-losing effects as well as a preparation method and application thereof, and belongs to the technical field of biomedical treatment. The invention aims to provide a composition which is more suitable for people. The invention provides a composition with lipid-lowering and weight-losing effects. The pharmaceutical composition is prepared from the following components: 1-50 parts of radix astragali, 1-50 parts of pericarpium citri reticulatae, 1-50 parts of fructus crataegi and 1-50 parts of medicated leaven. The invention provides a lipid-lowering pharmaceutical composition with higher practicability.

The invention relates to carrageenan special for empty capsules and a preparation method and application of the carrageenan, and belongs to the field of material science, the method comprises the following steps: dissolving carrageenan as a raw material in an acid solution with the pH value of 3.1-3.5 to prepare a glue solution with the mass percent of 10%, carrying out hydrolysis by utilizing acidification high temperature, stopping hydrolysis until the viscosity is 300-2000mPa. S, and cooling to room temperature to obtain the carrageenan. And neutralizing, dialyzing to remove impurities, drying and crushing to obtain the carrageenan special for the empty capsule. According to the invention, carrageenan is partially degraded by controlling reaction conditions, only the fragment size of the carrageenan is reduced, the obtained low-viscosity carrageenan does not lose the gelling property and film-forming property and can successfully replace gelatin to prepare hollow capsules, a new raw material is provided for hollow capsule products, the problem that the use amount of macromolecular carrageenan applied to the hollow capsules is limited is solved, and the application prospect is wide. The current situation that carrageenan empty capsules do not exist in the market is solved.

The present invention provides Lactobacillus rhamnosus ( Lacticaseibacillus rhamnosus )The application of NKU FL1‑8 in resisting obesity, serum inflammation and cognitive impairment caused by a high-fat diet belongs to the field of microbial technology. The present invention finds that Lactobacillus rhamnosus NKU FL1‑8 can significantly reduce the increase of adipose tissue caused by a high-fat diet, alleviate liver damage caused by a high-fat diet, inhibit serum inflammation caused by a high-fat diet, improve cognitive impairment caused by a high-fat diet, strengthen the intestinal barrier, increase the content of short-chain fatty acids in the cecum and feces, regulate the intestinal flora, and increase the diversity of the intestinal flora, thereby effectively resisting related diseases caused by a high-fat diet.

This invention discloses the application of the HERP gene knockout mouse model in obesity and metabolic disorders. The invention found that, compared to the wild-type high-fat diet group, HERP gene knockout leads to earlier and more severe obesity in mice fed a high-fat diet, with increased fat percentage, aggravated adipose tissue inflammation, and phenotypes such as dyslipidemia and glucose metabolism disorders. Furthermore, HERP gene knockout results in increased adipocyte differentiation. This indicates that HERP gene knockout mice are more sensitive to nutrition, develop obesity more quickly on a high-fat diet, and exhibit more severe symptoms such as adipose amplification, adipose tissue inflammation, and glucose and lipid metabolism disorders. This model can be used for molecular mechanism research and drug screening of obesity, adipose tissue disorders, and glucose and lipid metabolism disorders. The invention further found that cilostazol can significantly alleviate obesity and lipid metabolism disorders caused by HERP gene deficiency in mice, but has no significant weight loss effect in mice with normal genotypes, providing a new strategy for precision treatment.

The present invention relates to the field of microbial technology, and in particular to a strain of animal-associated Lactobacillus LA-1, a microbial preparation and an application thereof. Animal Lactobacillus ) LA‑1 has been deposited in the General Microbiology Center of China National Committee for the Preservation of Microbiological Cultures on September 27, 2024, with the deposit address at No. 3, Yard No. 1, Beichen West Road, Chaoyang District, Beijing, and the deposit number is CGMCC No. 32098. Animal-associated Lactobacillus LA‑1 has the effect of significantly reducing cholesterol content and bile salt hydrolase activity, and can inhibit α-glucosidase activity, has a high fatty acid absorption rate, is safe and sensitive to commonly used antibiotics, can relieve obesity, reduce blood lipids and liver lipid accumulation, relieve liver lipid degeneration and fat hypertrophy, has the effect of protecting the liver and enhancing liver function, and has good application prospects in the preparation of functional products.