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Reagent feeder for inner ear round window membrane

A round window film and applicator technology, applied in the field of medical devices, can solve the problems of drug eustachian tube loss, infection, complicated technology, etc.

Inactive Publication Date: 2007-09-12
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage is also that the drug is easily lost through the eustachian tube, which can easily cause otitis media and perforation of the tympanic membrane
[0006] ③Implantable microperfusion pump: When the implantable microperfusion pump is implanted, it is used as a tympanic membrane flap of the external auditory canal, and the microtube is introduced into the tympanic cavity, and the tip is placed in the niche of the round window. The microtube is connected to the micropump, and the drug is passed through the microtube pump Into the niche area of ​​the round window, the drug in the micro-perfusion pump will lose its effectiveness after a certain period of time, and the residual drug solution in the niche area of ​​the round window cannot be eliminated when the drug is administered again, which reduces the effective concentration of the drug in contact with the round window membrane
[0007] ④ Administration directly to the scala tympani of the perilymph through the opening of the cochlear bone wall, although it is a good method in theory
However, the technology is relatively complicated, and there are shortcomings such as inner ear damage and infection, so it is only used in animal experiments.

Method used

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  • Reagent feeder for inner ear round window membrane

Examples

Experimental program
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Effect test

Embodiment 1

[0018] Embodiment 1 The present invention is a fork-shaped double-lumen catheter, which consists of three parts: a head 1 , a body 2 , and a tail 3 . The length of the body 2 of the catheter is 40 mm, and it is longitudinally divided into two cavities with an inner diameter of 1 mm; the length of the two branches 1-1 of the head 1 is 15 mm, and the inner diameter is 1 mm, and the outlet matches a medical 1ml syringe; the tail 3 bulging, length is 6mm, inner diameter at the widest part is 4mm, the end opening of the tail 3 is a round window membrane sucker 3-1, the side width is 2mm, the edge is soft and covered with a layer of bio-adhesive patch.

Embodiment 2

[0019] Embodiment 2 The present invention embeds a metal electrode 4 in the interval between the two cavities of the body. The total length of the electrode is 57mm. It is inserted into the medicine storage chamber from the bifurcation of the head. The spherical diameter is 0.5mm, and the length of the outer end 4-2 is 15mm, and all the other are the same as embodiment 1.

Embodiment 3

[0020] Embodiment 3 The outer wall of the body of the present invention is provided with a skin fixing ring 5 with an inner diameter of 8 mm and an outer diameter of 12 mm, and the rest are the same as in Embodiment 2.

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Abstract

The present invention relates to medical equipment technology, and is one inner ear round window membrane administration device for treating inner ear diseases. The administration device is one forked-head two cavity duct comprising one duct head, one duct body and one duct tail. The duct body is divided longitudinally into two cavities communicated separately to two forked branches of the duct head, and each of the two branches has one joint in the outlet for connection to syringe cylinder. The duct tail is expanded to form one medicine storing chamber communicated to two cavities in the duct body, and has one round window membrane sucker in the end opening. One metal electrode inserted into the partition between two cavities has outer end extending beyond the head fork and spherical inner end inserted into the medicine storing chamber. One skin fixing ring is set in the outer wall of the duct body. The present invention is reliable, convenient and determined in healing effect.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to an inner ear round window membrane applicator for treating inner ear diseases through the round window membrane. Background technique [0002] Clinically, inner ear diseases (sensorineural deafness, vertigo, tinnitus, etc.) are common and frequently-occurring diseases in otolaryngology. When administered systemically, the absorption and distribution of many drugs are significantly restricted due to the existence of the blood-labyrinth barrier in the inner ear, and very little drug actually enters the inner ear, and the therapeutic effect is neither accurate nor ideal. In recent years, with the in-depth research on the anatomy and pathophysiology of the inner ear including the round window membrane, it has become possible to maintain a certain local effective concentration of drugs for a long time. Penetration through the round window membran...

Claims

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Application Information

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IPC IPC(8): A61M31/00A61M37/00A61F11/00
Inventor 周义德
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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