62 results about "Inner Ear Diseases" patented technology

An apparatus for displacing a partition between a middle ear and an inner ear to treat the symptoms of Meniere's disease or endolymphatic hydrops comprises a treatment member for being disposed in the middle ear adjacent the partition and a driver for driving the treatment member to move against the partition to thereby displace the partition at an infrasonic frequency to influence fluid distribution in the inner ear. A method for treating an ear comprises the steps of disposing a treatment device within the middle ear and moving at least a portion of the treatment device against the partition at an infrasonic frequency to displace the partition to influence fluid in the inner ear.

Apparatus and method for treating a disease or condition of the ear, such as Meniere's disease or endolymphatic hydrops, includes a manual device operable by hand to pressurize air and pressure transmitting arrangement for delivering the pressurized air to the middle ear, preferably in pulses, to displace the partition between the middle ear and the inner ear to influence fluid in the inner ear.

An implantable fenestration electrode delivers electrical stimulation signals for treatment of Meniere's disease. An electrode lead contains one or more signal wires for carrying a stimulation signal. An electrode tip at a terminal end of the electrode lead is configured for placement within a fenestration opening in an outer surface of a bony labyrinth of a patient with Meniere's disease without penetrating or impairing intra-labyrinthine membranes or neural tissue, and is adapted to deliver the stimulation signal via intra-labyrinthine fluid to the intra-labyrinthine neural tissue.

Provided is a small and lightweight device for treating Meniere's disease and similar conditions that is transported by a patient and gives a safe and correct treatment when used by the patient. The portable device treats Meniere's disease and similar conditions by introducing pressure pulses to the ear canal so as to vibrate the auditory ossicles through the tympanic membrane. It comprises a pump unit for generating the pressure pulses, the earpiece for transmitting the pressure pulses to the tympanic membrane, and the controller for controlling the pump unit. The period, pressure, width, and frequency of the pressure pulses are adjustable.

The present invention relates to medical equipment technology, and is one inner ear round window membrane administration device for treating inner ear diseases. The administration device is one forked-head two cavity duct comprising one duct head, one duct body and one duct tail. The duct body is divided longitudinally into two cavities communicated separately to two forked branches of the duct head, and each of the two branches has one joint in the outlet for connection to syringe cylinder. The duct tail is expanded to form one medicine storing chamber communicated to two cavities in the duct body, and has one round window membrane sucker in the end opening. One metal electrode inserted into the partition between two cavities has outer end extending beyond the head fork and spherical inner end inserted into the medicine storing chamber. One skin fixing ring is set in the outer wall of the duct body. The present invention is reliable, convenient and determined in healing effect.

An isosorbide preparation as a therapeutic agent for Meniere's disease that is improved with respect to administrability properties, such as bitterness, without detriment to the requisite performance of rapid efficacy exertion. There is provided an isosorbide-containing jelly preparation characterized by containing not only isosorbide but also agar. Preferably, cacao powder is further contained. The amount of agar added is preferably in the range of 0.3 to 2 w / w% based on the whole of jelly preparation. Further, there is provided a process for producing an isosorbide-containing jelly preparation, characterized by comprising mixing together at least agar, isosorbide and water, heating for dissolution and cooling to room temperature or below.

The invention discloses a medicament for treating Meniere's disease, which comprises (by weight ratio) cane sugar 50-600, hairy vein agrimony 30-600, Chinese date 20-400, rhizoma Gastrodiae 15-300, borneol 10-100 and alisol 10-100.

A low-capacity intravenous injection of gastrodine for treating neurasthenia, neurasthenia syndrome, cerebral trauma syndrome, dizziness, Meniere's disease, reuralgia, headache, etc is prepared from gastrodine, the water for injection and metallic chelating agent. Its preparing process is also disclosed.

The present invention relates to a medicine intravenous injection preparation and its preparation method. The helicid powder injection preparation described by said invention for intravenous drop-injection is formed from (by wt%) 30-99.9% of helicid and 0.1-70% of water soluble medicinal auxiliary material. Said invention can be mainly used for curing neurasthenic syndrome, angioneuralgia, sudden deafness, vestibular neuronitis, vertebrobasilar ischemia and post-traumatic brain syndrome, etc. Specially it can obtain obvious therapeutic effect for curing vertiginous diseases, such as Meniere's disease, drug-induced vertigo and traumatic vertigo, etc.

The invention discloses a medicine for treating Meniere's disease and a preparation method thereof. The medicine is prepared from the following ingredients in parts by mass: 1 part of uncaria, 1 part of rhizoma pinellinae praeparata, 1 part of chrysanthemum, 1 part of poria cocos, 1 part of bamboo shavings, 1 part of atractylodes macrocephala, 1 part of selfheal, 1 part of radix rehmanniae, 1 part of plantain seed, 1 part of radix achyranthis bidentatae, 1 part of Chinese wolfberries, and 1 part of nacre mother of pearl. The preparation method of the medicine comprises the following steps: according to the mass ratio, purchasing clean first-class uncaria, rhizoma pinellinae praeparata, chrysanthemum, poria cocos, bamboo shavings, atractylodes macrocephala, selfheal, radix rehmanniae, plantain seed, radix achyranthis bidentatae, Chinese wolfberries, and nacre mother of pearl, removing the residual impurities respectively, and soaking the materials in cool boiled water for half an hour for standby application; placing the soaked medicinal materials and the clear liquid for soaking the medicinal materials together into an earthenware pot, adding an appropriate amount of cool boiled water, decocting the materials for twice with strong fire first and slow fire later, decocting for the first time for 50 minutes, filtering the medicinal liquid, then adding warm boiled water to perform decoction for the second time for 55 minutes, combining the liquids, and concentrating the combined liquid to obtain 540 ml of traditional Chinese medicinal liquid with a concentration of 50%.

An application of the yellowsteam milkwort as Chinese-medicinal materials in prepairng the medicines to treat Meniere's disease is disclosed. Its decoction or water-soluble component has also the function of promoting blood circulation and improving immunity.

The invention discloses a traditional Chinese medicine composition used for treating Meniere's disease. The traditional Chinese medicine composition is prepared from following raw materials, by weight, 15 to 20 parts of radix bupleuri, 15 to 20 parts of rhizoma pinelliae, 10 to 15 parts of radix scutellariae, 15 to 20 parts of radix codonopsis, 10 to 16 parts of ginger, 4 to 8 parts of fructus jujubae, 6 to 10 parts of licorice, 10 to 15 parts of rhizoma alismatis, 10 to 14 parts of Uncaria tomentosa, 3 to 5 parts of fritillaria cirrhosa, 3 to 5 parts of angelica sinensis, 3 to 5 parts of radix codonopsis, and 1 to 3 parts of nacre mother of pearl. Drug effect of the traditional Chinese medicine composition used for treating Meniere's disease is obvious, and cure rate is high.

The present invention relates to preventive and / or therapeutic agents for Meniere's disease, which comprise a leukotriene antagonist (such as pranlukast hydrate) as an active ingredient. Leukotriene antagonists (such as pranlukast hydrate) are effective in ameliorating various symptoms, such as hearing impairment, tinnitus, a feeling of fullness in the ear and vertigo, thus being useful as a preventive and / or therapeutic agent for Meniere's disease.

The invention relates to a medicine for treating Meniere's disease, which is prepared from the following active pharmaceutical ingredients: Chinese wolfberry, Chinese yam, uncaria, gastrodia tuber, tuckahoe, rhizoma alismatis, schisandra fruit, licorice root, vinegar roasted magnet and stir-fried spina date seed. The active pharmaceutical ingredients can be made into tablets, pills, capsules and oral liquids. The medicine can condition the function balance of the liver, spleen and kidney, and has the advantages of favorable treatment effect and no toxic or side effect, and the effective treatment rate is 89.7%.

Disclosed herein are methods and kits useful for providing neuroprotection to neurons in the inner ear and to methods of treating inner ear diseases and disorders, including tinnitus and Mnire's disease.

The invention belongs to the technical field of medical equipment, in particular to an inner ear low-frequency shear stress vibrator for treating Meniere's disease. So far, the principle of endolymphatic shunt for treating the Meniere's disease is that the endolymph is manually opened to replace the non-functional endolymphatic sac in order to ease endolymphatic hydrops. However, the therapeutic theory is challenged by a clinical research specifically designed by Denmark. The invention designs the vibrator which carries out non-invasive low-frequency shear stress on an inner ear via mastoid process skin, and determines a release method and parameters. The clinical application of the vibrator can remove the pain of patients with Meniere's disease receiving treatment in operations, eliminate any risk in operative treatment and remarkably reduce medical cost, thus benefiting the patients and the society.

The invention discloses a medicine for treatment of Meniere's disease and a preparation method of the medicine for treatment of Meniere's disease. The medicine is composed of, by weight, 1-3 parts of alisma and 1-3 parts of atractylodes rhizome. The preparation method includes the steps: selectively purchasing high-quality clean alisma and atractylodes rhizome according to weight parts, removing residual impurities and dust, and putting into cold water for immersion for about half an hour until permeation of medicine tissues is completed; putting the soaked medicine and clear liquor into a casserole, filling cold boiled water in a lever 33mm higher than the medicine to carry out decoction for the first time for 35min, pouring medicine liquor out, filling warm boiled water for decoction for the second time for 30min, mixing the medicine liquor and concentrating to obtain 570ml 50% medicine liquor.

Novel methods and compositions for the local treatment of Meniere's disease, tinnitus and hearing loss employ a therapeutically effective amount of a prostaglandin of the F-type to the inner ear. The treatment can be either continuous or intermittent and may involve the use of pumps, gels, or slow release drug inserts.

The invention provides an oral medicine for treating Meniere's disease and a preparation method thereof. The oral medicine comprises the following components in parts by mass: 1-3 parts of bamboo shavings stir-baked with ginger juice, 1-3 parts of rhizome pinelliae preparata, 1-3 parts of dried orange peel, 1-3 parts of poria, 1-3 parts of radix glycyrrhizae preparata, 1-3 parts of immature bitter orange, 1-3 parts of kudzuvine root, 1-3 parts of salvia miltiorrhiza, 1-3 parts of uncaria and 1-3 parts of raw loadstone. The preparation method of the oral medicine comprises the following steps: purchasing high-quality and clean first-class bamboo shavings stir-baked with ginger juice, rhizome pinelliae preparata, dried orange peel, poria, radix glycyrrhizae preparata, immature bitter orange, kudzuvine root, salvia miltiorrhiza, uncaria and raw loadstone in parts by mass, removing residual impurities from the components respectively, and soaking the components in cold boiled water for half an hour for later use; and placing the soaked components and supernatant, which is obtained by soaking the components in the cold boiled water, into a medicine-decocting machine, pouring cold boiled water into the medicine-decocting machine until the water level in the medicine-decocting machine is 35mm above the components, performing primary decocting for 30 minutes, performing filtering to obtain decoction I, pouring warm boiled water into the medicine-decocting machine, performing secondary decocting for 25 minutes to obtain decoction II, mixing the decoction I and the decoction II, performing concentration to obtain 1,800 ml of 50% traditional Chinese medicine liquid, bagging and sealing the traditional Chinese medicine liquid, and keeping the traditional Chinese medicine liquid fresh in a refrigerator for later use.

The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine preparation for treating Meniere's disease and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following medicines: prepared rehmannia root, dragon bone, wolfberry fruit, poria cocos, fingered citron, rhizoma cyperi, round cardamom fruit, rhizoma curculiginis, rhizoma typhonii, adenophora tetraphylla, schisandra chinensis and rhizoma arisaematis. The traditional Chinese medicine preparation is reasonable in composition, easy to prepare and has significant curative effecton eliminating dampness and eliminating phlegm, dredging meridians and tonifying the liver and kidneys; therefore, the traditional Chinese medicine preparation is an effective medicine for treating Meniere's disease, in particular to liver-kidney yin deficiency type Meniere's disease.

The invention provides a middle ear compression apparatus, which comprises an apparatus main body, wherein the apparatus main body comprises a facial mask and a drum body; the facial mask is a flexible rubber facial mask; a hollow cavity is formed in the facial mask; two nasal plugs are symmetrically arranged on the surface of an inner shell of a nasal area of the facial mask; the nasal plugs protrude out of the surface of the inner shell of the facial mask outwards; the nasal plugs and the inner shell of the facial mask are subjected to integral design; the nasal plugs are flexible rubber nasal plugs; a first conduit and a second conduit are arranged in the two nasal plugs; and one end of the first air conduit and one end of the second air conduit communicate with the hollow cavity of thefacial mask. The middle ear compression apparatus provided by the invention, on the basis of the principle that five senses communicate with each other, can change pressure changes of middle ears bychanging air pressures of an oral cavity and a nasal cavity, so that pressure and flow of inner ears can be affected, and dizziness symptom in patient with meniere's disease can be effectively improved; and the middle ear compression apparatus is simple to operate, convenient to use, safe and effective and is broad in application scope.

The invention relates to a traditional Chinese medicine composition used for treating vertigo, comprising the following components according to parts by weight: 80 to 120 parts of agrimony, 10 to 30 parts of astragalus root, 5 to 15 parts of white atractylodes rhizome, 5 to 15 parts of rhizoma alismatis and 0.8 to 2.0 parts of ginger; preferably, 90 to 110 parts of agrimony, 15 to 25 parts of astragalus root, 8 to 12 parts of white atractylodes rhizome, 8 to 12 parts of rhizoma alismatis and 1.0 to 1.5 parts of ginger. The traditional Chinese medicine composition is suitable for treating vertigo caused by turbid phlegm obstruction and the Meniere's disease, and the total effective rate is as high as 95.0%.

The invention discloses a traditional Chinese medicine preparation for treating Meniere's disease. The adopted medicine raw materials comprises the following components by weight: 10-20 g of cassia twig, 10-20 g of chamomile, 10-20 g of herba lycopi, 8-12 g of albizia flower, 8-12 g of uncaria, 8-12 g of Fructus Lycii, 8-15 g of charred triplet, 10-20 g of Magnetite, 8-12 g of Concha Margaritifera, 5-10 g of Concha Haliotidis, and 5-10 g of lamber. The selected medicine raw materials have the synergy effects of eliminating phlegm, freeing channels, calming the liver, suppressing Yang, extinguishing wind, easing nerves, removing blood stasis; through clinical application, the traditional Chinese medicine preparation is found to have a remarkable curing effect, can cure completely without relapse and without side or toxic effects, and is worthy of popularization and application.

The invention provides application of a DNA tetrahedral nanostructure as a carrier of a medicine for treating inner ear diseases. The DNA tetrahedral nanostructure reaches inner ear functional cells through round window injection. According to the invention, a mouse round window administration technology successfully proves that the DNA tetrahedral nanostructure can enter inner ear functional cells. Therefore, the enrichment of the DNA tetrahedral nanostructure in the hearing hair cell part of the inner ear is realized for the first time, and a new way is provided for conveying medicines for treating inner ear diseases. Meanwhile, nucleic acid molecules are natural and have the advantages of low toxicity, excellent biocompatibility and the like, and the synthesis price of framework nucleic acid is low (the injection cost of each time is about several yuan), so that the DNA tetrahedral nanostructure provided by the invention is an ideal drug carrier for treating inner ear diseases.

The invention discloses a traditional Chinese medicine formulation for treating Meniere's syndrome. Peach seeds, ground beetles, angelica dahurica, immature bitter oranges, rhizoma alismatis, codonopsis pilosula, rhizoma atractylodis macrocephalae, poria, rhizoma gastrodiae and pinellia tuber which are Chinese medicinal herbs are adopted as raw materials and decocted to be decoction or made into a powdered medicament. The formulation has the efficacy of promoting blood circulation, activating collaterals, dispelling wind and invigorating spleen, can quickly control symptoms, causes no adverse reaction, and ensures that symptoms are not easy to relapse.

The present invention provides compositions containing (i) a pharmaceutically active agent selected from a group consisting of an arylcycloalkyamine of a derivative, analogue or pharmaceutically active salt thereof, and (ii) a biocompatible polymer or a combination of biocompatible polymers. The compositions or medicaments containing these compositions may be used for the prevention and / or treatment of inner ear diseases, e.g. tinnitus.

The invention discloses a traditional Chinese medicinal preparation for treating Meniere's disease and a preparation method thereof, belonging to the field of traditional Chinese medicine. The traditional Chinese medicinal preparation comprises the following effective components: Cryptotympana pustulata slough, Radix Polygalae (Polygala tenuifolia and / or Polygala sibirica), Cornus officinalis, Semen Cassiae (Cassia obtusifolia and / or Cassia tora), Aeschynomene indica root, Polygonatum odoratum, Aristolochia cathcartii, Fructus Amomi Rotundus (Amomum kravanh and / or Amomum compactum), Leersia hexandra, Micromeria biflora, Akebia quinata, Lycoris radiata, Ziziphus jujuba (Semen Ziziphi Spinosae), Angelica dahurica, Perilla frutescens and Acorus calamus. The traditional Chinese medicinal preparation of the invention has reasonable formulation which meets the theory of traditional traditional Chinese medicine and modern medicine research, has effects of suppressing hyperactive liver for calming endogenous wind, promoting the circulation of qi and relieving stagnation, can treat different symptoms of Meniere's disease, can thoroughly cure Meniere's disease, and has the advantages of no recurrence, good safety and no adverse effects, and fills in the blank of Meniere's disease drugs.