Low-acid gingko flavones and extracting method thereof
A technology of ginkgo flavonoids and an extraction method is applied in the directions of medical raw materials derived from Ginkgo biloba, metabolic diseases, cardiovascular system diseases, etc.
Inactive Publication Date: 2008-12-24
石金龙
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Problems solved by technology
The current common extraction method, the extraction rate is mostly lower than 2%, and there are three main contents, the content of ginkgo flavonoids is less than 24.5%, and the content of ginkgolide is less than 6.3%. These two are the main substances that produce pharmacological effects, but there is another The content of ginkgolic acid is about 10PPM, which is harmful to human body
Method used
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Embodiment
[0020] Grinding the harvested ginkgo leaves; adding ethanol to soak it; reclaiming the ethanol after soaking (to be used next time); removing impurities; adding resin for adsorption for the first time (except ginkgolic acid); eluting with ethanol to obtain eluted liquid; add resin adsorption for the second time (remove ginkgolic acid); elute with ethanol to obtain eluent; recover ethanol (to be used next time); dry it to obtain low-acid ginkgo flavonoids, pulverize and pack.
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Abstract
The invention discloses low-acid ginkgo flavone and an extraction method thereof. The invention is characterized in that the content of the ginkgo flavonoid glycosides of the low-acid ginkgo flavone is over 27 percent, the content of ginkgolides is over 6.5 percent, and the content of ginkgoic acid is lower than 1PPM. The low-acid ginkgo flavone is extracted according to the following method: crushing folium ginkgo, marinating the crushed folium ginkgo in ethanol; recollecting the ethanol used for marinating the crushed folium ginkgo; removing impurities from the marinated folium ginkgo; adding resin to absorb the ginkgoic acid for the first time; eluting with ethanol so as to obtain an eluting solution; adding resin to absorb the ginkgoic acid for the second time; eluting with ethanol so as to obtain an eluting solution; recollecting the ethanol; obtaining the low-acid ginkgo flavone after the drying. Compared with other extraction methods, the extraction efficiency of the low-acid ginkgo flavone extracted through the adoption of the method is improved by 0.2 percent, the content of the ginkgo flavonoid glycosides is improved by 3 percent, the content of the ginkgolides is improved by 0.5 percent and the content of ginkgoic acid is lower than 1PPM.
Description
technical field [0001] The invention relates to a ginkgo flavonoid, in particular to a low-acid ginkgo flavonoid and an extraction method. Background technique [0002] The main purpose of ginkgo flavonoids is to produce medicines or health care products. Its main function is to lower blood fat and blood pressure, soften blood vessels and other effects. It is extracted from Ginkgo biloba leaves. The current common extraction method, the extraction rate is mostly lower than 2%, and there are three main contents, the content of ginkgo flavonoids is less than 24.5%, and the content of ginkgolide is less than 6.3%. These two are the main substances that produce pharmacological effects, but there is another The content of ginkgolic acid is about 10PPM, which is harmful to human body. Contents of the invention [0003] The purpose of this invention is to provide a kind of low-acid ginkgo flavonoids and its extraction method, so that the content of ginkgo flavonoids and ginkgoli...
Claims
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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/16A61P3/06A61P9/12A61K127/00
Inventor 石金龙
Owner 石金龙
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