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Magnetic resonance imaging method and uses thereof

A technology of magnetic resonance imaging and water molecules, applied in the field of medical testing, can solve the problems of high cost of inspection, affecting sensitivity, low tissue resolution and spatial resolution, etc., and achieve the effect of improving curative effect and survival period.

Inactive Publication Date: 2009-05-13
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

Among them, CT-enhanced examination is the most widely used technology in clinical practice. However, due to the radiation damage of CT itself, its repeated use is limited. At the same time, the tissue resolution of CT imaging is relatively low, which also affec

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0008] Example 1: Clinical application of magnetic resonance diffusion weighted imaging (DWI) in the follow-up after transarterial chemoembolization of liver cancer: compared with DSA

[0009] Methods: 16 patients who underwent transarterial chemoembolization (TACE) for liver cancer included 14 males and 2 females, aged 23-78 years, with a median age of 59.5 years.

[0010] DWI examination: 1.5T MR imager (GE Company), 8-channel phased array soft body coil, all patients for diffusion weighted imaging (DWI). Main imaging parameters: ASSET correction, SE-EPI acquisition, b=0 and 500s / mm2, direction ALL, TR / TE6000ms / 60ms, slice thickness 7mm, interval 0.5mm, FOV 28cm, matrix 256*256, NEX 2, breath-hold scan , scan time 24s.

[0011] Angiography (DSA) examination method: Under the guidance of Toshiba rotary digital subtraction angiography machine, all patients were approached through the femoral artery, routinely underwent skin preparation, disinfection, draping, and local anesth...

Embodiment 2

[0014] Example 2: Correlation study between tumor apparent diffusion coefficient (ADC) and maximum enhancement value of enhanced CT examination

[0015] Methods: 16 patients who underwent transarterial chemoembolization (TACE) for liver cancer included 14 males and 2 females, aged 23-78 years, with a median age of 59.5 years.

[0016] DWI examination: 1.5T MR imager, 8-channel phased array soft body coil, all patients for diffusion weighted imaging (DWI). Main imaging parameters: ASSET correction, SE-EPI acquisition, b=0 and 500s / mm2, direction ALL, TR / TE 6000ms / 60ms, slice thickness 7mm, interval 0.5mm, FOV 26-28cm, matrix 256*256, NEX 2 , breath-hold scan, scan time 24s.

[0017] Upper abdominal CT enhanced examination method: use 16-slice spiral CT scanner, 120KV, 250mAs, pitch 15, rack rotation time 0.5s, acquisition slice thickness 1mm, reconstruction slice thickness 7mm, interval 0.8mm, use non-ionic for enhancement Type contrast agent, the dosage is calculated accordi...

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PUM

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Abstract

The invention relates to the medical assay technology field, in particular to a magnetic resonance imaging method for monitoring tumor activity tissues after tumor therapy, which aims to effectively monitor residual or recrudescent tumor activity tissues in time by diffusion-weighted MR imaging (DWI), working out an individualized tumor therapeutic schedule which is reasonable and effective, and increasing curative effect and survival period of a patient. The provided imaging method is used for predicting tumor active ingredients through MR, and is a video picture method which indirectly reflects information such as tissue structure, cellular metergasis and the like through detecting the changes of water molecule motion state in biological tissues. The invention further provides concrete implementation parameters and steps for monitoring the tumor activity tissues after tumor therapy by adopting the magnetic resonance imaging method.

Description

technical field [0001] The invention relates to the technical field of medical detection, in particular to a magnetic resonance imaging method and the application of the method in monitoring tumor active tissues after tumor treatment. Background technique [0002] Malignant tumors are one of the main diseases that endanger human health. Timely and effective monitoring of tumor residual or recurrent active tissue after tumor treatment is an important guarantee for improving the efficacy of tumor treatment, prolonging patient survival and life treatment. Clinically, the means of monitoring tumor curative effect are mainly medical imaging methods, such as CT (computer tomography, CT), MRI (Magnetic Resonance Imaging, MRI) and PET (positron emission tomography, PET) and so on. Among them, CT-enhanced examination is the most widely used technology in clinical practice. However, due to the radiation damage of CT itself, its repeated use is limited. At the same time, the tissue res...

Claims

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Application Information

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IPC IPC(8): A61B5/055
Inventor 袁正刘士远叶晓丹许立超肖湘生
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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