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Systems and methods for detecting flow and enhancing SNR performance in photoacoustic imaging applications

A technology for photoacoustic imaging and imaging systems, applied in applications, diagnosis using light, blood flow measurement, etc., can solve problems such as flickering artifacts dependence, cannot be reduced or eliminated, and achieve the effect of enhancing SNR performance

Inactive Publication Date: 2010-10-13
KONINK PHILIPS ELECTRONICS NV
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Problems solved by technology

The Beard application cannot reduce or eliminate flicker artifacts mainly due to its reliance on Doppler shift

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  • Systems and methods for detecting flow and enhancing SNR performance in photoacoustic imaging applications
  • Systems and methods for detecting flow and enhancing SNR performance in photoacoustic imaging applications
  • Systems and methods for detecting flow and enhancing SNR performance in photoacoustic imaging applications

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Embodiment Construction

[0025] As mentioned herein above, the present disclosure provides a method for advantageously combining photoacoustic and thermoacoustic imaging with power Doppler (PD) techniques to detect reduced flow velocity, for example, with enhanced signal-to-noise ratio (SNR) performance. systems and methods.

[0026] It is well known, eg in the field of telecommunications, to employ coded excitations to increase the SNR of transmitted signals. In particular, binary sequences can be used to encode signals that are subject to noise or interference for transmission over a medium. The signal is received and decoded to recover media information. Systems and methods that combine the use of coded excitation with the well-known benefits of the Doppler effect, especially in photoacoustic imaging applications, can prove to be very beneficial for weak signal processing. In this regard, reference is made to commonly assigned co-pending provisional patent application entitled "Coded Excitation F...

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Abstract

The present disclosure provides systems and methods for combining photoacoustic / thermoacoustic imaging with power Doppler signal processing. More particularly, the disclosed systems and methods involve use of encoded Doppler signals in order to detect and image in vivo blood flow. The disclosed flow detection systems and methods may be used in photoacoustic imaging using PD to achieve, inter alia, enhanced signal-to-noise (SNR) and sensitivity performances. A method for detecting flow in a target region may involve (i) obtaining a encoded signal containing photoacoustic imaging data for the target region using a photoacoustic imaging system, (ii) decoding the encoded signal, (iii) passing the decoded signal through a demodulator and a low-pass filter, resulting in a base-band signal, (iv) passing the base-band signal through a wall filter, resulting in an uncluttered signal; and (iv) estimating the Ro value by integrating the power spectrum of the uncluttered signal.

Description

[0001] Cross References to Related Applications [0002] This application is related to commonly assigned provisional patent application entitled "Coded Excitation For Photo-Acoustic and Thermo-Acoustic Imaging," filed June 29, 2007, with assigned Serial No. 60 / 947,078. The entire contents of the aforementioned Provisional Patent Application are hereby incorporated by reference. technical field [0003] The present disclosure relates to photoacoustic imaging and thermoacoustic imaging. More specifically, the present disclosure relates to systems and methods for generating spatial distributions of flow in photoacoustic and thermoacoustic imaging applications. Background technique [0004] Blood flow is the fundamental mechanism for carrying nutrients, oxygen, and regulatory proteins to biological tissues and back with metabolic exhaust gases. Angiogenesis is now widely accepted as the single most important factor in maintaining tumor growth and proliferation (see, eg, J. Fo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B5/026
CPCA61B5/0261A61B5/0095A61B5/0059
Inventor Y·王
Owner KONINK PHILIPS ELECTRONICS NV
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