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Medicinal composition for improving sleep and preparation method thereof

A technology for improving sleep and composition, applied in the field of medicine, can solve the problems of increasing and decreasing incidence of insomnia, adverse reactions and the like, and achieve the effects of simple preparation method and clear preparation effect

Inactive Publication Date: 2011-05-25
王念军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Human beings spend one-third of their time in sleep, and the relationship between sleep and health has gradually attracted attention. With the advancement of modernization, social competition has become increasingly fierce, and lifestyles have also changed, resulting in an increasing incidence of insomnia. Long-term insomnia is harmful to the physical and mental health of the human body, and it is easy to cause multiple organ dysfunction and immune function decline, and it is also related to ulcer disease, hypertension, coronary heart disease, diabetes and other mental diseases. In recent years, the development of A variety of sleep-improving drugs and health products have been used. Although they are sure to improve sleep, most of them contain animal hormones and have adverse reactions, so they are not suitable for long-term use.

Method used

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Embodiment Construction

[0012] Below adopt clinical data to prove the beneficial effect of medicine of the present invention.

[0013] 1. Materials and methods:

[0014] 1. Materials

[0015] 1.1 Take 140 Kunming mice, weighing 18-22g, provided by Sichuan University.

[0016] 1.2 Medicinal solution of the present invention: Ganoderma lucidum 10g, Semen jujubee 9g, Lycium barbarum 8g, Glycyrrhizae 6g, Ume 8g are decocted with water for 3 times, adding 8 times the amount of water each time, decocting for 2 hours, 1 hour and 1 hour respectively, and the filtrate Concentrated to make each ml of liquid medicine contains 0.1g of crude drug. The medicinal solution of the present invention is formulated into three doses, i.e. high, medium and low doses (respectively equivalent to 20, 10 and 5 times of the recommended dose for the human body).

[0017] 1.3 Sodium pentobarbital is a product of Shanghai Xingzhi Chemical Factory.

[0018] 1.4 Melatonin is a product of Jiangsu Changzhou Medical Technology Dev...

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PUM

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Abstract

The invention belongs to the field of medicaments, and in particular relates to a medicinal composition for improving sleep and a preparation method thereof. The invention aims to provide the medicinal composition for improving sleep, which is used for enhancing deep sleep and improving sleep quality. The medicinal composition is prepared by taking the following components in part by weight as raw materials: 6 to 12 parts of lucid ganoderma, 6 to 12 parts of spina date seed, 3 to 8 parts of medlar, 6 to 10 parts of licorice root and 6 to 10 parts of smoked plum; and adding pharmaceutically acceptable auxiliary materials. A pharmacological test proves that the medicinal composition can remarkably prolong sodium pentobarbital sleep time, and has no obvious effect on a latent period of sodium pentobarbital sleep, namely the medicinal composition can be used for enhancing the deep sleep and improving the sleep quality.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to a pharmaceutical composition for improving sleep and a preparation method thereof. Background technique [0002] Human beings spend one-third of their time in sleep, and the relationship between sleep and health has gradually attracted attention. With the advancement of modernization, social competition has become increasingly fierce, and lifestyles have also changed, resulting in an increasing incidence of insomnia. Long-term insomnia is harmful to the physical and mental health of the human body, and it is easy to cause multiple organ dysfunction and immune function decline, and it is also related to ulcer disease, hypertension, coronary heart disease, diabetes and other mental diseases. In recent years, the development of A variety of sleep-improving drugs and health products have been prescribed. Although they are sure to improve sleep, most of them contain animal hormones and have ad...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61K9/00A61K9/16A61K9/48A61K9/14A61P25/20
Inventor 王念军
Owner 王念军
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