Effect of morinda officinalis extract on improving or treating sexual disorder, and application thereof

A technology of Morinda officinalis extract and sexual function, which is applied in the fields of food and medicine, and can solve problems such as no research reports

Inactive Publication Date: 2011-09-28
CHENGDU YIPING MEDICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0017] Although Morinda officinalis has been reported to improve sexual dysfunction, the effect of Morinda officinalis extract (Morinda officinalis oligosaccharides) on the overall regulation of hypothalamus-

Method used

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  • Effect of morinda officinalis extract on improving or treating sexual disorder, and application thereof
  • Effect of morinda officinalis extract on improving or treating sexual disorder, and application thereof
  • Effect of morinda officinalis extract on improving or treating sexual disorder, and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0157] Preparation of Morinda officinalis extract:

[0158] Weigh 1000g of Morinda officinalis, crush it into a coarse powder, put it in a container, add 30% ethanol, the volume of alcohol is 6 times the amount of Morinda officinalis, reflux extraction three times, each time for 2 hours, combine the extracts, filter, and filtrate in Concentrate on a rotary evaporator at 60°C to form an extract, add ethanol until the alcohol content reaches more than 90%, let it stand for 24 hours, filter, add water to dissolve the precipitate, add activated carbon and boil for 15 minutes, filter, and concentrate the filtrate under reduced pressure, according to " Add ethanol until the alcohol content reaches more than 90%" step and process again, and the obtained extract is spray-dried to obtain a powder extract, white or light yellow powder, with a yield of 5%. After content analysis, the extract contains Morinda officinalis Oligosaccharides and polysaccharides, the total content of these sub...

Embodiment 2

[0160] Preparation of Morinda officinalis extract:

[0161] Weigh Morinda officinalis, crush it into a coarse powder, put it in a container, add 20% dilute ethanol, the volume of alcohol is 8, 6, and 4 times the amount of Morinda officinalis, reflux extraction three times, each time for 2 hours, and combine the extracts , filtered, the filtrate was concentrated on a rotary evaporator at 60°C to form an extract, added ethanol until the alcohol content reached more than 90%, stood still for 24 hours, filtered, dissolved in water, added activated carbon and boiled for 15 minutes, filtered, the filtrate reduced Concentrate under pressure, and process again according to the steps of "adding ethanol until the alcohol content reaches more than 90%", and spray-dry the obtained extract to obtain a powdery extract, white or light yellow powder, with a yield of 6%. After content analysis, the The extract contains Morinda officinalis oligosaccharides and polysaccharides, and the total con...

Embodiment 3

[0163] Preparation of Morinda officinalis extract:

[0164] Weigh Morinda officinalis, crush it into a coarse powder, put it in a container, add 20% dilute methanol, the volume of alcohol is 8, 6, and 4 times the amount of Morinda officinalis, reflux extraction three times, each time for 2 hours, and combine the extracts , filtered, the filtrate was concentrated on a rotary evaporator at 60°C to form an extract, added methanol until the alcohol content reached more than 90%, stood still for 24 hours, filtered, dissolved in water, added activated carbon and boiled for 15 minutes, filtered, the filtrate reduced Concentrate under pressure, and process it again according to the steps of "adding methanol until the alcohol content reaches more than 90%". The obtained extract is spray-dried to obtain a powdery extract, white or light yellow powder, with a yield of 6%. After content analysis, the The extract contains Morinda officinalis oligosaccharides and polysaccharides, and the to...

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Abstract

The invention relates to the effect of a morinda officinalis extract on improving or treating sexual disorder, and an application thereof. The substance for treating or improving the sexual disorder has an effect on integrally regulating the hypothalamus, the pituitary gland, the sex gland and the adrenocortical function to improve or treat the sexual disorder, and simultaneously has selective specificity on different 5-HT receptors, i.e., the substance can selectively excite the 5-HT1 receptor, but has no excitation on the 5-HT2 receptor and the 5-HT3 receptor. The morinda officinalis extract can be used as a medicament and/or food for treating or assisting to improve the sexual disorder.

Description

technical field [0001] The invention relates to the fields of medicine and food. Specifically, the invention designs a substance containing Morinda officinalis extract (Morinden officinalis oligosaccharide) for treating or improving sexual dysfunction and its application. The substance for treating or improving sexual dysfunction has the effect of improving or treating sexual dysfunction through the overall regulation of hypothalamus-pituitary-gonad and adrenal cortex functions, and has selective effects on different 5-HT receptors. Specificity, such substances can selectively excite 5-HT1 receptors, but have no excitatory effect on 5-HT2 receptors and 5-HT3 receptors. Drugs and / or foods that can be used to treat or assist in improving sexual dysfunction. Background technique [0002] Morinda [0003] Latin scientific name: Morinda officinalis How Chinese name: Morinda officinalis [0004] Family: Rubiaceae [0005] Genus: Morinda officinalis [0006] Part used: root ...

Claims

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Application Information

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IPC IPC(8): A61K36/746A61K31/4415A61K33/04A61K31/593A61P15/00A61P15/10A61K31/355A61K31/592A61K33/06A23L1/29A61K31/375A61K31/525A23L1/28A61K125/00A61K31/51A23L33/00
Inventor 张乃元杨强张祖兵王雅包旭
Owner CHENGDU YIPING MEDICAL SCI & TECH
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