Chromatographic detection device and method

Abstract

The invention relates to a chromatographic detection device, which comprises a chromatographic column, a detection unit, a switching unit and a control unit, wherein the chromatographic column is connected with the detection unit through the switching unit; the detection unit comprises at least two detection modules; the switching unit is used for selectively communicating the chromatographic column with one of the at least two detection modules by adjusting pressure; the control unit is connected with the switching unit and switching gas respectively; and the control unit is used for controlling the switching unit to further control direction of driving a sample by the switching gas, so that the sample which gets out of the chromatographic column is driven by the switching gas to enter the detection module communicated with the chromatographic column. The invention also provides a chromatographic detection method. The device and the method have the advantages of more detection modes, convenience and fastness in switching, small dead volume, long life of the detector and the like.

Description

technical field [0001] The invention relates to a detection device and method, in particular to a multi-mode detection device and method applied in the field of chromatography. Background technique [0002] Mass detectors and concentration detectors are two types of detectors commonly used in gas chromatographic analysis instruments. Especially in the field of complex sample detection, it has great advantages to use them in series. Partially selective concentration-type detectors (such as photoionization detectors (PID), electron capture detectors, etc.) have high sensitivity, but have little response to saturated alkanes, while hydrogen flame ionization detectors in mass-type detectors (FID) responds to all organics, but is less sensitive than selective concentration-type detectors. At present, in order to solve the detection of multi-component trace-level samples in complex matrices, a high-sensitivity concentration detector and a mass detector are usually used in series ...

AI Technical Summary

Problems solved by technology

[0005] At the same time, in order to reduce the widening of the components separated by the chromatographic column in the pipeline, the makeup gas is usually placed at the front of the PID, but this simple physical series connection reduces the sensitivity of the PID detector

[0006] 2) When testing high-concentration samples, the PID detector is easily saturated, and it is easy to cause contamination of the UV lamp window of the PID detector

[0007] 3) The use mode of the series detector is relatively fixed, and it is impossible to perform multi-mode detection such as using a single FID detector to test high-concentration samples.

[0008] In addition, the traditional valve switching technology can also realize the switching of the flow path, but the valve switching is prone to sample adsorption pollution and dead volume problems caused by moving parts

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