5results about How to "Small dead volume" patented technology

The invention discloses an emulsion preparation device and an emulsion preparation method using the same, the device comprises a mixer main body, a liquid inlet conduit, a liquid outlet conduit and a feeding assembly, the mixer main body has a three-way flow channel structure, an optional flow channel is a liquid outlet flow channel, the other two flow channels are liquid inlet flow channels, the liquid outlet conduit is communicated with the liquid outlet flow channel, and the feeding assembly is communicated with the liquid inlet flow channel. The liquid inlet guide pipe is communicated with the liquid inlet flow channel, and the feeding assembly is communicated with the liquid inlet guide pipe. The method for preparing the emulsion comprises the steps that the dispersed phase and the mobile phase are obtained, the continuous phase and the dispersed phase are put into the two liquid inlet flow channels of the mixer body through the liquid inlet guide pipes by means of the feeding assembly, the emulsion formed after mixing flows out of the liquid outlet flow channels and is collected, the flow speed ratio of the continuous phase to the dispersed phase is 2: 1-4: 1, and the total flow speed is 60-750 mL / min. According to the scheme, the emulsion with the appropriate particle size is prepared at the low flow speed, the feeding temperature range is wide, the device is simple, the channel dead volume is small, and the device is suitable for both laboratories and industrial production.

This invention discloses a laboratory-grade ceramic membrane pressure filtration device, comprising a pressure ceramic membrane filtration unit, a pressure pump, a feed container, a valve, and a dialysate container. This invention uses an inorganic ceramic membrane as the filter medium, which is resistant to acids and alkalis, resistant to organic solvents, has a wide range of applications, high strength, and high operating pressure. It maintains high membrane integrity during installation, disassembly, and filtration, and offers high operating flux and high recovery rate. It can withstand both high-pressure steam sterilization and chemical sterilization. The sealing method is simpler than that of tubular ceramic membranes, and the dead volume is significantly smaller, requiring relatively less feed solution, making it suitable for laboratory operating environments.

This invention discloses a tangential flow filtration separation device and a method for determining the drug content of liposomal drugs, relating to the field of liposomal drug filtration and determination technology. The device includes a filtration separation component, a gas control component, a drive component, and system piping and valve components. The filtration separation component includes a porous membrane filtration unit, with the inner cavity of the membrane forming a mother liquor flow path, and the outer cavity connected to a filtrate collection unit. The drive component is connected to the mother liquor flow path, and the gas control component is also connected to the mother liquor flow path. The system piping and valve components connect the filtration separation component, the gas control component, and the drive component to form a closed-loop flow path. This invention solves the problems of existing methods, such as difficulty in efficiently and stably separating free drugs from liposomal components, cumbersome operation, easy liposomal leakage, and sample loss and dilution, which seriously affect the accuracy of detection.

The invention discloses a 3D printing pump-free sample injection point discharge atomic emission spectrum analysis device and method for detecting arsenic, and belongs to the technical field of atomic emission spectrum analysis. Comprising a 3D printing integrated device, an external gas path system and a spectrum detection system, the 3D printing integrated device comprises a 3D printing module, a quartz glass sheet, a quartz capillary tube, two tungsten filament electrodes and a microsyringe; the external gas path system comprises a small argon steel cylinder, two argon pipelines, a gas flow meter and a trace gas flow meter; the spectrum detection system comprises an optical fiber and a small CCD spectrometer. The method comprises the following steps: injecting an arsenic-containing solution sample into a reaction chamber of a 3D printing device by using a microsyringe, converting the arsenic-containing solution sample into a gaseous analyte through hydride generation, blowing the gaseous analyte into a discharge chamber by argon, exciting an atomic emission spectrum of arsenic by using micro plasma, radially collecting a spectral signal from the outside of a quartz capillary by using a bare optical fiber, and transmitting the spectral signal to a CCD (Charge Coupled Device); and finally, the concentration of the arsenic in the sample can be obtained through calculation. The method has the characteristics of high excitation efficiency, strong anti-interference capability, low cost, open source sharing, environmental friendliness and the like.

This utility model relates to the technical field of chemical process monitoring equipment, specifically a time-sharing oxygen concentration monitoring device for dual reactors. It has two symmetrically distributed sampling branches, each equipped with a reactor. A common gas path module is located outside the sampling branches, including three-way solenoid valves V1 and V2, a main solenoid valve VT, and purge gas systems connecting V1, V2, and VT respectively. The main solenoid valve VT is also connected to an oxygen analyzer. This utility model mainly achieves pollution-free switching monitoring of two reactors by a single oxygen analyzer through a symmetrical three-way valve group and a positive pressure isolation structure, reducing equipment investment and operation and maintenance costs, improving instrument lifespan and analytical efficiency, and simultaneously reducing the probability of direct equipment damage.