The invention discloses an HSK ultrasonic tool handle structure with an automatic tool replacement function. The HSK ultrasonic tool handle structure comprises an HSK tool handle, a retainer, a wireless power emitting end, a wireless power receiving end, an ultrasonic transducer and a pressing plate. A tool clamping portion is formed on the periphery of the end, close to the ultrasonic transducer, of the HSK tool handle and is located under the wireless power receiving end. The HSK ultrasonic tool handle structure is ingenious in design, a wireless power transmission mode is adopted, a series problems of abrasion and low rotation speed of spindles due to traditional sliding ring modes are effectively solved, and the operation stability of an ultrasonic motorized spindle is improved, and the structure has the advantages of high stability, high rotation speed, high precision and long service life; the wireless power receiving end is suspended on the motorized spindle through the retainer, dismounting and mounting are convenient, the HSK tool handle and the spindle are relatively independent, and convenience is brought to daily use and replacement; the tool clamping portion is located under the wireless power receiving end, automatic tool replacement is possible, and automatic tool handle replacement and placement of a tool changer are achieved.