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Check method of atopic dermatitis

A technology for atopic dermatitis and inspection methods, which can be applied to material inspection products, measuring devices, instruments, etc., can solve problems such as difficulty in judging treatment effect or treatment progress, and achieve the effect of simple inspection and reduction of burden.

Active Publication Date: 2012-08-29
FUAN KERU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Since atopic dermatitis is repeatedly exacerbated and remitted, it is difficult to judge the effect of treatment or to judge the progress of treatment, and it is expected to develop a new diagnostic method

Method used

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  • Check method of atopic dermatitis
  • Check method of atopic dermatitis
  • Check method of atopic dermatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0029] Hereinafter, the present invention will be explained in detail by citing examples, however, the present invention is not limited to these examples.

[0030] A. Method

[0031] (1) How to take the skin stratum corneum

[0032] For 4 female patients diagnosed with atopic dermatitis, using a keratin tester (2.5cm×2.5cm: manufactured by Asahibiomed) to remove the stratum corneum using a keratin tester (2.5cm×2.5cm: manufactured by Asahibiomed) on the neck skin of 4 female patients who were diagnosed with atopic dermatitis. In addition, samples were taken on the upper arm skin that had never shown symptoms of dermatitis.

[0033] Similarly, samples were taken from the neck skin and upper arm skin of 3 healthy women as controls.

[0034] (2) Method of extracting protein from skin stratum corneum

[0035] Take 200ul of 1% SDS / PBS(-) into the homogenization tube, and put the cuticle inspection tool after the above tape peeling into it, and rub the adhesive surface with a homogenizing pes...

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Abstract

The invention aims to provide a check method of atopic dermatitis, which will not bring any burden to a user. By a scotch tape method, skin cuticle can be sampled without any wound, and the atopic dermatitis can be diagnosed by detecting the amount of HSP27 obtained by the sample.

Description

Technical field [0001] The invention relates to an inspection method for diagnosing atopic dermatitis and judging its therapeutic effect. Background technique [0002] Atopic dermatitis is a disease that manifests as skin inflammation, macula, and eczema. Atopic dermatitis is generally considered to be a chronic skin disease accompanied by itching, which is caused by an allergic constitution (atopic quality) that easily causes atopic bronchial asthma, allergic rhinitis, dermatitis and urticaria, plus various stimuli. Approximately 80% of patients have the onset of the disease before the age of 5 years. Previously, it was thought that it would be cured naturally in school-age children. However, in recent years, the number of cases that continue to adulthood, or the number of onset or recurrence after adulthood has continued to increase. It is usually an incurable disease, and may be confused with other dermatitis patients in the early stages. [0003] In addition to steroids, ant...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/68
CPCG01N33/544G01N33/6881G01N2800/20
Inventor 石渡潮路
Owner FUAN KERU
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