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How to check for atopic dermatitis

A technique for atopic dermatitis and skin, applied in the field of atopic dermatitis inspection, can solve problems such as difficult judgment of treatment effect or judgment of treatment progress, and achieve the effect of simple inspection and reduced burden

Active Publication Date: 2015-08-26
FUAN KERU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Since atopic dermatitis is repeatedly exacerbated and remitted, it is difficult to judge the effect of treatment or to judge the progress of treatment, and it is expected to develop a new diagnostic method

Method used

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  • How to check for atopic dermatitis
  • How to check for atopic dermatitis

Examples

Experimental program
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Embodiment

[0029] Hereinafter, the present invention will be described in detail by citing examples, however, the present invention is not limited to these examples.

[0030] A. method

[0031] (1) How to take the stratum corneum of the skin

[0032] For 4 female patients diagnosed with atopic dermatitis, the neck skin showing dermatitis was peeled off with 5 tapes using a horny tester (2.5 cm×2.5 cm: manufactured by Asahibiomed Co., Ltd.), and the horny layer was collected. In addition, samples were similarly sampled from the skin of the upper arm that never showed symptoms of dermatitis.

[0033] Similarly, samples were taken from the neck skin and upper arm skin of 3 healthy females as controls.

[0034] (2) Protein extraction method in skin stratum corneum

[0035] Take 200ul of 1% SDS / PBS(-) into the tube for homogenization, put into it the cuticle detection tool that has been peeled off the above-mentioned tape, rub the adhesive surface with a pestle for homogenization, and remo...

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PUM

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Abstract

The invention aims to provide a check method of atopic dermatitis, which will not bring any burden to a user. By a scotch tape method, skin cuticle can be sampled without any wound, and the atopic dermatitis can be diagnosed by detecting the amount of HSP27 obtained by the sample.

Description

technical field [0001] The present invention relates to an inspection method for diagnosing atopic dermatitis and judging its therapeutic effect. Background technique [0002] Atopic dermatitis is a disease that manifests as skin inflammation or macules, eczema. Atopic dermatitis is generally considered to be a chronic skin disease accompanied by itching caused by allergic constitution (atopic diathesis) that easily causes atopic bronchial asthma, allergic rhinitis, dermatitis and urticaria, and various stimuli. About 80% of the patients had onset in childhood before the age of 5. Previously, it was thought that the disease would be cured spontaneously in school-age children, but in recent years, cases that persist into adulthood, or cases of onset or relapse after adulthood have continued to increase. It is usually an incurable disease and may be confused with other dermatitis patients in its early stages. [0003] Treatment methods for atopic dermatitis (allergic dermat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/68
CPCG01N33/544G01N33/6881G01N2800/20
Inventor 石渡潮路
Owner FUAN KERU
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