Device and method for detecting biological tissue of pressure modulation near infrared spectrum

A technology of near-infrared spectroscopy and biological tissue, which is applied in the field of pressure-modulated near-infrared spectroscopy to realize biological tissue detection, can solve the problems of measurement spectrum error, inaccurate measurement position positioning, and influence on modeling and prediction accuracy, so as to improve measurement confidence Noise ratio, increasing light penetration depth, and improving the effect of effective penetration depth

Active Publication Date:
View PDF6 Cites 28 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, during the measurement process, the differences between individuals or different parts of the same individual and the inaccurate positioning of the measurement parts can also easily cause measurement spectrum errors and affect the accuracy of modeling predictions.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Device and method for detecting biological tissue of pressure modulation near infrared spectrum
  • Device and method for detecting biological tissue of pressure modulation near infrared spectrum
  • Device and method for detecting biological tissue of pressure modulation near infrared spectrum

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0044] The device and method for detecting biological tissue by pressure-modulated near-infrared spectroscopy of the present invention will be described in detail below with reference to the embodiments and the accompanying drawings.

[0045] On the basis of the pressure modulation spectrum detection device, the present invention measures the deformation of biological tissue under different pressures, the magnitude of the pressure and the change of the diffuse reflection spectrum. The measurement wavelength range is 1100nm-1700nm. According to the spectrum measurement results in this wavelength range, Obtain the change of free water and bound water content in the tissue.

[0046] The main components of biological tissue are water, protein, fat, etc. The main absorption groups and their absorption peaks are shown in Table 1:

[0047] Table 1

[0048]

[0049] Biological tissue is rich in water, with a volume ratio of more than 70%. According to its existing form, it can be ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a device and a method for detecting biological tissue of pressure modulation near infrared spectrum. Biological tissue physiological status judgment and volume difference spectrum measurement are achieved according to pressure and spectrum measuring results in the process of deformation of the biological tissue: changing of biological tissue diffuse reflection spectrum along with the pressure and action time is respectively measured, multiplicative scatter correction and second derivative processing are conducted to the measured spectrum, content change of free water and bound water is obtained, fitting processing is conducted to the content change of the free water and the bound water, the pressure and the action time, biological tissue status is judged according to a fitting curve trend; differential treatment is conducted to diffuse reflection spectrum obtained under different pressure values, the water content change in the tissue is taken as a reference, physiological background of the tissue is deducted, and spectrum net analyte signals of tissue elements are obtained. According to method for detecting the biological tissue of the pressure modulation near infrared spectrum, rapid detecting of physiological status of the biological tissue is achieved, and spectrum detection accuracy of the tissue elements is improved.

Description

technical field [0001] The present invention relates to a device and method for measuring properties and components of biological tissue. In particular, it relates to a device and method for pressure-modulated near-infrared spectroscopy to realize biological tissue detection. Background technique [0002] The main components of biological tissue include protein, fat, water, etc., and the water in the tissue accounts for about 70% of the total volume of the biological tissue. basis. In the study of non-destructive testing of biological tissue components and physiological and pathological states, the mechanical and optical properties of biological tissue are closely related to the physiological morphology and function of biological tissue. By measuring the mechanical and optical parameters of biological tissue, not only can biological tissue For the diagnosis of physiological state, the specific content of various components can also be measured. In previous studies, differ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/47
Inventor 徐可欣李晨曦
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap