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Composition for enhancing memory and learning ability

A composition and memory technology, applied in the directions of drug combinations, plant raw materials, medical preparations containing active ingredients, etc., to achieve the effects of effective prevention and treatment, improving memory or learning ability, and inhibiting the reduction of memory or learning ability

Active Publication Date: 2015-08-26
KOREA FOOD RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Tacrine was developed as an existing acetylcholinesterase inhibitor, but due to some side effects such as gastrointestinal disturbances, it is necessary to search for inhibitory active ingredients from natural food materials for application

Method used

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  • Composition for enhancing memory and learning ability
  • Composition for enhancing memory and learning ability
  • Composition for enhancing memory and learning ability

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0067] Hereinafter, the present invention will be described in more detail through examples. These embodiments are only to illustrate the present invention more specifically. According to the gist of the present invention, the scope of the present invention is not limited to these embodiments, which is obvious to those skilled in the art to which the present invention belongs.

[0068] 【Example】

[0069] Throughout this specification, "%" is used to express the concentration of a specific substance, unless otherwise mentioned, solid / solid is (weight / weight)%, solid / liquid is (weight / volume)% and Liquid / liquid is (vol / vol) %.

[0070] 【Experimental materials and methods】

[0071] Artemisia annua used in the experiment was purchased from the website of Jecheon Traditional Chinese Medicine (http: / / www.jchanbang.com) and pulverized with a blender (blender) KA2610 (Jworldtech, Korea). Add 80% ethanol at a ratio of 1:10 to 2 kg of pulverized Artemisia annua powder, and extract 6 ...

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Abstract

The present invention relates to a composition for promoting memory or learning ability and to a composition for preventing and treating cognitive impairment, which comprise one, two or more plant extracts selected from the group consisting of Artemisia apiaceae extract, Illicium verum extract and Lepidium apefalum extract. The present invention has the effect of inhibiting neural cell damage, especially, neural cells of the basal part of the cerebrum by inhibiting acetylcholinesterase activity and through antioxidative activity (for example, inhibiting the generation of oxidative reactive species) and affinity for an NMDA receptor. The compositions of the present invention may have the effect of not only promoting memory or learning ability by protecting neural cells and preventing damage to neural cells but also of preventing and treating diseases caused by cognitive impairment. In addition, according to the present invention, Lepidium apefalum extract is provided as basic substance for pharmaceuticals or food which has efficacy in promoting memory or learning ability or efficacy for preventing and treating cognitive impairment.

Description

【Technical field】 [0001] The present invention relates to a composition for improving memory and learning ability, which contains Artemisia annua extract, star anise extract or Tinglizi extract as active ingredients. 【Background technique】 [0002] There are a total of 100 billion neurons in the human brain, and they are connected to other neurons around each other by an average of about 10,000 parts called synapses, forming a neural network. Through these synapses, close information transmission is realized between multiple neurons. At this time, it is neurotransmitters that play the role of mediators. Multiple neurons exchange information with each other by releasing neurotransmitters to stimulate receptors. The way the human brain stores memories is the process of strengthening the connection strength of synapses through continuous chemical stimulation and electrical stimulation. This process is called long-term potentiation (LPT, long-term potentiation), which will stre...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/282A61K36/235A61K36/31A61P25/28A61P25/00
CPCA61K36/79A61K36/23A61K36/282A61K36/31A61K36/57A61P25/00A61P25/28A61K2300/00
Inventor 李昌镐金仁镐韩大锡金荣彦朴东俊崔俊赫李惠星曹承睦
Owner KOREA FOOD RES INST
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