Microfluidic microbial culture detection chip
A microbiological culture and detection chip technology, applied in the field of microfluidics, can solve the problems of inability to measure concentration and lack of detection structure for culture fluid
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[0030] The microfluidic optical comparison chip of Todd Thorsen, etc. can only detect specific fluorescently labeled bacteria, and cannot achieve multi-channel bacterial suspension culture on the chip. Suspension culture is a very important step for microbial screening. It provides specific microbial growth conditions and determines the elimination and retention of certain characteristics of strains.
[0031] Although the microfluidic microbial culture chips disclosed in Chinese Patent Nos. CN201110316751.0 and CN201110142095.7 solve the problem of microorganisms being cultured in suspension on the chip, they can only provide indicators of the growth rate of microorganisms and cannot detect changes in the concentration of specific substances in the culture solution Condition. The detection of the concentration of specific substances in the culture medium is an important basis for judging the quality of the strain, and it is very important for the screening of the strain.
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