Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Levodopa preparation and application thereof

A technology of levodopa and preparations, applied in the field of medicine, can solve the problems of no reports, increased levels of catecholamines and corticosteroids, reduce the speed and degree of induced hypothermia, and treat curative effects, etc., to improve consciousness disorders, make up for the gaps in drugs, overcoming the effects of chills

Inactive Publication Date: 2015-11-25
CHINA REHABILITATION RES CENT
View PDF4 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the relatively recognized early brain protection measure is hypothermia therapy, but it has serious obstacles, that is, while inducing hypothermia, it will be accompanied by side effects such as chills, catecholamines, and corticosteroid levels, which will significantly reduce the speed of inducing hypothermia , degree and therapeutic effect
In addition, in the prior art, there are almost no reports of brain protection drugs specifically aimed at the early intervention of brain dysfunction due to ischemic hypoxic brain injury after cardiopulmonary resuscitation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Levodopa preparation and application thereof
  • Levodopa preparation and application thereof
  • Levodopa preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The levodopa preparation comprises 70% of levodopa and 30% of benserazide in terms of weight percentage; it is made into tablets by a conventional preparation method.

Embodiment 2

[0039] The levodopa preparation comprises 80% of levodopa and 20% of benserazide in terms of weight percentage, and is made into tablets by a conventional preparation method.

Embodiment 3

[0041] The levodopa preparation comprises 90% of levodopa and 10% of benserazide in terms of weight percentage, and is made into tablets by a conventional preparation method.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to levodopa preparation and application thereof. The levodopa preparation comprises, by weight percentage, 70-90% of levodopa and 10-30% of benserazide. The levodopa preparation has the advantages that the levodopa preparation contains the levodopa and the benserazide of fixed content, is applicable to rehabilitation treatment of cerebral dysfunction after cerebral resuscitation, and provides medicine for treating cerebral dysfunction caused by hypoxia-ischemia brain damage after cardio-pulmonary resuscitation; the preparation can be used to prepare medicine for repairing cerebral ischemia-reperfusion injury, medicine for the rehabilitation treatment of cerebral dysfunction after cerebral resuscitation, medicine for treating hypoxia-ischemia brain damage and medicine for replenishing body dopamine; meanwhile, a new purpose of levodopa is provided.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a levodopa preparation and its application. Background technique [0002] With the continuous improvement of the medical level, cardiopulmonary resuscitation technology has been continuously improved in recent years, but the incomplete recovery of brain function after successful cardiopulmonary resuscitation is still an important obstacle affecting the rehabilitation of patients. [0003] According to statistics, only 10% to 30% of patients with successful cardiopulmonary resuscitation recover well, and most of the survivors have brain dysfunction such as consciousness, language, cognition, and movement. So far, the treatment measures for cerebral resuscitation are very limited. The more commonly used method is to minimize the no-flow time and low-flow time in the early stage, that is, the cardiopulmonary cerebral resuscitation (CPCR) to quickly restore the effective heart rhythm. ), as ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/198A61P9/10A61P9/00A61P25/28A61K31/165
Inventor 刘丽旭王文竹赵立希张通
Owner CHINA REHABILITATION RES CENT
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com