Levodopa preparation and application thereof

Abstract

The invention relates to levodopa preparation and application thereof. The levodopa preparation comprises, by weight percentage, 70-90% of levodopa and 10-30% of benserazide. The levodopa preparation has the advantages that the levodopa preparation contains the levodopa and the benserazide of fixed content, is applicable to rehabilitation treatment of cerebral dysfunction after cerebral resuscitation, and provides medicine for treating cerebral dysfunction caused by hypoxia-ischemia brain damage after cardio-pulmonary resuscitation; the preparation can be used to prepare medicine for repairing cerebral ischemia-reperfusion injury, medicine for the rehabilitation treatment of cerebral dysfunction after cerebral resuscitation, medicine for treating hypoxia-ischemia brain damage and medicine for replenishing body dopamine; meanwhile, a new purpose of levodopa is provided.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a levodopa preparation and its application. Background technique [0002] With the continuous improvement of the medical level, cardiopulmonary resuscitation technology has been continuously improved in recent years, but the incomplete recovery of brain function after successful cardiopulmonary resuscitation is still an important obstacle affecting the rehabilitation of patients. [0003] According to statistics, only 10% to 30% of patients with successful cardiopulmonary resuscitation recover well, and most of the survivors have brain dysfunction such as consciousness, language, cognition, and movement. So far, the treatment measures for cerebral resuscitation are very limited. The more commonly used method is to minimize the no-flow time and low-flow time in the early stage, that is, the cardiopulmonary cerebral resuscitation (CPCR) to quickly restore the effective heart rhythm. ), as ...

AI Technical Summary

Problems solved by technology

[0004] At present, the relatively recognized early brain protection measure is hypothermia therapy, but it has serious obstacles, that is, while inducing hypothermia, it will be accompanied by side effects such as chills, catecholamines, and corticosteroid levels, which will significantly reduce the speed of inducing hypothermia , degree and therapeutic effect

In addition, in the prior art, there are almost no reports of brain protection drugs specifically aimed at the early intervention of brain dysfunction due to ischemic hypoxic brain injury after cardiopulmonary resuscitation

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