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Chinese medicinal preparation for prevention and treatment of myelosuppression after radiotherapy and chemotherapy

A technology of myelosuppression and traditional Chinese medicine preparations, applied in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of simple supplementation and single treatment ideas, and achieve the goal of improving clinical symptoms and preventing severe infection and fever Effect

Active Publication Date: 2019-07-30
朱晓婷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] CN 200910181378.5 discloses a traditional Chinese medicine for the treatment of myelosuppression, although it is a compound prescription traditional Chinese medicine, but it is simple supplementation, and the treatment idea is relatively simple

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Prescription: Codonopsis 20g, Astragalus 60g, Ligustrum lucidum 20g, Eclipta 20g, Millae Spatholobus 30g, ginger 6 g, Bupleurum 10g. Peanut shell 30g, Polygonatum 20g.

[0029] Typical case: Zhao XX, male, 56 years old, Fengnan District, Tangshan City; Diagnosis: Lung cancer On December 31, 2015, 7 days after chemotherapy, blood cell analysis showed: WBC1.9×10 9 / L, Hb80g / L, plc46×10 9 / L; Symptoms: general fatigue, dry mouth, night sweats, pale red tongue with stagnant veins at the bottom of the tongue, deep and thready pulse; treatment: oral Chinese medicine granules prepared by the above prescription, and blood cell analysis after taking three doses in a row: WBC3 .2×109 / L, Hb110g / L, plc101×10 9 / L, no adverse reactions.

Embodiment 2

[0031] Prescription: Codonopsis 15g, Astragalus 30g, Ligustrum lucidum 15g, Eclipta 15g, Millae Spatholobus 20g, peanut 15g, sealwort 15g, ginger 10g, Bupleurum 15g.

[0032] Typical case: Meng Defen, female, 52 years old, Luannan County, Tangshan City; Diagnosis: rectal cancer Blood cell analysis after chemotherapy on October 8, 2015: WBC2.02×10 9 / L, Hb100g / L, plc56×10 9 / L; general fatigue, tenesmus, pale and red tongue with stagnant veins at the bottom of the tongue, deep and thready pulse; floating inch pulse; low-grade fever of 37.3 degrees Celsius after catching a cold, with exogenous tendency, Bupleurum and ginger for additional treatment: Orally prepared from the above prescription Chinese traditional medicine granules, take 5 batches in a row to measure blood cell analysis: WBC4.5×10 9 / L, Hb115g / L, plc96×10 9 / L;, no adverse reactions.

Embodiment 3

[0034] Prescription: Codonopsis 10g, Astragalus 15g, Ligustrum lucidum 15g, Eclipta 10g, Millae Spatholobus 15g, Peanut 10g, Polygonatum 10g, Ginger 6g, Bupleurum 10g.

[0035] Typical case: Liu XX, male, 63 years old, Xiangfengli Community, Tangshan City; Diagnosis: gastric cancer Blood cell analysis: WBC1.6×10 3 days after chemotherapy on January 11, 2015 9 / L, Hb79g / L, plc55×10 9 / L; Fatigue, poor diet, pale dark red tongue with greasy yellowish fur, stagnant venation on the bottom of the tongue, deep and thready pulse; the patient's tongue coating shows a little suffocation and heat, the tonic medicine of this prescription is heavy, and the tonic medicine is reduced for fear of being in love with evil Dosage, treatment: Orally take the traditional Chinese medicine granules prepared by the above prescription, take the medicine for Wufu, the symptoms are relieved, blood cell analysis: WBC3.9×10 9 / L, Hb106g / L, plc90×10 9 / L;, no adverse reactions. (Small dosage of medici...

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Abstract

The invention relates to a traditional Chinese medicine preparation for preventing and treating bone marrow suppression after radiotherapy and chemotherapy. The traditional Chinese medicine preparation is prepared from, by weight, 10-20 parts of codonopsis pilosula, 15-60 parts of astragali radix, 15-20 parts of fructus ligustri lucidi, 10-20 parts of eclipta alba, 15-30 parts of caulis spatholobi, 10-30 parts of peanut coat, 10-20 parts of rhizoma polygonati, 6-10 parts of ginger and 10-15 parts of radix bupleuri. The traditional Chinese medicine preparation has the advantages of good curative effect and low cost, has the curative effect similar to GM-CsF on the aspect of leukopenia (including severe bone marrow suppression) after radiotherapy and chemotherapy, can improve the clinical symptoms, has no obvious side effect, and meanwhile can effectively improve blood platelet and hemoglobin values and effectively prevent adverse consequences, such as serious infection and fever caused by leukocyte decrease.

Description

technical field [0001] The invention relates to a traditional Chinese medicinal preparation for oral administration, in particular to a traditional Chinese medicinal preparation for preventing and treating myelosuppression after radiotherapy and chemotherapy. Background technique [0002] Myelosuppression is a decrease in the activity of blood cell precursors in the bone marrow. Both red and white blood cells in the bloodstream originate from stem cells in the bone marrow. Blood cells in the bloodstream are short-lived and need to be constantly replenished. Stem cells, the precursors of blood cells, must divide rapidly for timely replenishment. Chemotherapy and radiation, as well as many other anti-tumor treatments, target rapidly dividing cells, resulting in suppression of normal bone marrow cells, blockage of blood cell production, and each component of blood cells is harmful to the body. It plays an indispensable role, and the reduction of any component will cause the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P7/06A61P7/00
CPCA61K9/1652A61K36/233A61K36/28A61K36/344A61K36/48A61K36/481A61K36/486A61K36/638A61K36/8969A61K36/9068A61K2300/00
Inventor 朱晓婷赵郁吕立丽孙虹雯王晓敏张凤珍
Owner 朱晓婷
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