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Method and device for preparing tissue

A tissue and three-dimensional porous technology, which is applied in tissue cell/virus culture devices, biochemical equipment and methods, and biological material sampling methods. Issues of time and money

Active Publication Date: 2018-11-02
SHENZHEN EXCELLENT TECH
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  • Description
  • Claims
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Problems solved by technology

[0002] Traditional 2D culture cannot help researchers obtain more cell data that is closer to normal physiological conditions. Another example is the traditional target-based drug development process that consumes a lot of time and financial resources, and the success rate of this process is quite high. low, its comprehensive performance is unsatisfactory

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  • Method and device for preparing tissue
  • Method and device for preparing tissue

Examples

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no. 1 example

[0040] In a first embodiment, the method of preparing tissue comprises:

[0041] Step 101, constructing a structural shape according to the shape structure of the cell tissue culture;

[0042] Specifically, a structural shape is constructed according to the shape structure formed by cell culture through UG software or other three-dimensional design software.

[0043] Step 102, constructing a three-dimensional porous structure of the structural shape according to the structural characteristics of the cells, the structural characteristics include the number of structural layers of the cells and the shape of the cells;

[0044] Specifically, design the interior of the structure according to the different cell sizes, and design a three-dimensional porous structure model with void shapes, regular order, and interconnected voids (the void size is 105-420 microns, suitable for cell culture) with reference to biomechanics. When designing, it can be deployed according to the requireme...

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Abstract

The embodiment of the invention discloses a method and device for preparing tissue. The method includes the steps that a structural shape is built according to a shape structure cultivated by cell tissue; a three-dimensional porous structure of the structural shape is built according to the structure characteristics of cells, wherein the structure characteristics comprise the structure layer numbers of the cells and the shapes of the cells; the three-dimensional porous structure is biologically printed into a cell culture body of a microenvironment system. The stable environment can be provided for growth of the cells accordingly, the tissue is close to the structure of tissue organs of the human body, the gap forming orientation is regular and ordered, and the problem that distribution of array culture cells is unordered can be solved; meanwhile, the method and device can be used for researching of some cell-culture-related tasks and medicine screening, and researchers are assisted in obtaining cell growth data closer to the normal physiological state.

Description

technical field [0001] The embodiments of the present invention relate to the field of biotechnology, in particular to a method and device for preparing tissue. Background technique [0002] Traditional 2D culture cannot help researchers obtain more cell data that is closer to normal physiological conditions. Another example is the traditional target-based drug development process that consumes a lot of time and financial resources, and the success rate of this process is quite high. Low, its overall performance is unsatisfactory. Contents of the invention [0003] The purpose of the embodiments of the present invention is to provide a method and device for preparing tissue, aiming at the problem of how to provide a stable environment for the growth of cells. [0004] To achieve this purpose, the embodiments of the present invention adopt the following technical solutions: [0005] In a first aspect, a method of preparing tissue, the method comprising: [0006] Construc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M3/00C12N5/09
CPCC12M21/08C12M33/00C12N5/0693C12N2513/00
Inventor 赵小文张东锋赵文平蔡君华
Owner SHENZHEN EXCELLENT TECH
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