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Round three-layer biological membrane with cross-shaped section

A cross-shaped, biofilm technology, applied in medical science, surgery, etc., can solve the problems of large volume area of ​​biocomposite film, small area of ​​fracture, biocomposite film degradation speed and time performance index can not meet clinical needs and other problems

Inactive Publication Date: 2018-02-02
锡山区东港晓鸣电子产品经营部
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. The biocomposite membrane has a relatively large volume area and a small fracture area, and 2 cannot be effectively fitted and fixed together
[0005] 2. The limitations of the current biocomposite membrane materials and manufacturing process lead to performance indicators such as the degradation rate of the biocomposite membrane and the time for the carried growth factors to release the effective drug concentration (the duration of the effective concentration is the key to the healing quality of the fracture line) Unable to meet clinical needs

Method used

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  • Round three-layer biological membrane with cross-shaped section
  • Round three-layer biological membrane with cross-shaped section

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Experimental program
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Effect test

Embodiment Construction

[0032] refer to figure 1 , 2 1. A circular three-layer biofilm 1 with a cross-shaped cross-section, including a hollow biofilm folded into a cross-shaped cross-section, with four corners "U", and the cross-section of the corners and the fracture line coincides. The inner layer of the biofilm is The elastic layer is a dense degradable or non-degradable biofilm, and the middle layer is a drug layer, which encapsulates a drug slow-release system that can promote bone healing. The material is biodegradable or biocompatible with human bone. The material to be absorbed, the outer guiding layer, is made of degradable or non-degradable, absorbent or non-absorbable porous and loose material that is biocompatible with human bone.

[0033] After the circular biofilm 1 with a cross-section is cut, four "U"-shaped unit biofilms 2 are formed.

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Abstract

The present invention provides a circular three-layer biofilm with a cross-section, including a hollow biofilm folded into a cross-section, with four corners "U", and the corners coincide with the fracture line section, and the inner layer of the biofilm It is an elastic layer, which is a dense degradable or non-degradable biofilm, and the middle layer is a drug layer, which encapsulates a drug slow-release system that can promote bone healing. The material is biodegradable or biocompatible with human bone. The absorbable material, the outer guiding layer, is made of degradable or non-degradable, absorbable or non-absorbable porous and loose material that is biocompatible with human bone.

Description

technical field [0001] The invention relates to a circular three-layer biofilm with a cross section. Background technique [0002] At present, it is a frontier field of medical research to use a biocomposite film containing growth factors / stem cells to stick to the fracture line to enhance the speed and quality of fracture healing. There are blood vessels and bone cells distributed on the inner surface of the fracture line (anastomosis line), and whether the healing is good depends on the growth of blood vessels and bone cells in the fracture line. The reason why biofilm sticking to the surface of fracture anastomosis can increase the quality of fracture healing is that on the one hand, the drugs encapsulated in the biofilm can promote the growth of blood vessels and bone cells in the fracture anastomosis, and on the other hand, the biological The membrane isolates external muscles and other human tissues from the fracture anastomotic line, and prevents the reaction of huma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/12A61L31/06A61L31/04A61L31/02A61L31/00A61L31/14A61L31/16
CPCA61L31/06A61L31/005A61L31/024A61L31/04A61L31/042A61L31/044A61L31/046A61L31/14A61L31/146A61L31/148A61L31/16A61L2300/108A61L2300/232A61L2300/252A61L2300/30A61L2300/412A61L2300/414A61L2300/602A61L2300/604C08L67/04C08L1/02
Inventor 王玉英
Owner 锡山区东港晓鸣电子产品经营部
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