Method and device for constructing genetic subtype prediction model and computer equipment

Abstract

The invention relates to a method and device for constructing a genetic subtype prediction model, computer equipment and a storage medium. The method comprises the following steps: receiving a gene expression profile of a training sample and a corresponding genetic subtype; according to a predetermined classification number, performing classification integration on the gene expression profile to obtain a target gene expression profile, wherein the target gene expression profile comprises categories corresponding to the number of the categories; selecting a target category from the categories of the target gene expression profile, and constructing a corresponding relation between the target category and the genetic subtype; and outputting a genetic subtype prediction model according to thecorresponding relation. By adopting the method, the genetic subtype prediction model can be obtained on the basis of a flexible corresponding relation constructed between the gene expression profile and the genetic subtype.

Description

technical field [0001] The present application relates to the field of biotechnology, in particular to a method, device, computer equipment and storage medium for constructing a genetic subtype prediction model. Background technique [0002] In traditional techniques, cytogenetic abnormalities can be determined based on characteristics such as gene expression levels, immunophenotypes, or fluorescence in situ hybridization, and then the corresponding relationship between the above characteristics and genetic subtypes can be obtained by analyzing multiple cases, and genetic subtypes can be constructed. However, this correspondence is simply to match the above characteristics of the case with the genetic subtype, which is less flexible and cannot guarantee that a representative correspondence can be extracted from it, resulting in the scope of application of the genetic subtype prediction model. narrow. With the development of biotechnology, the study of organisms can go deep ...

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Problems solved by technology

[0002] In traditional techniques, cytogenetic abnormalities can be determined based on characteristics such as gene expression levels, immunophenotypes, or fluorescence in situ hybridization, and then the corresponding relationship between the above characteristics and genetic subtypes can be obtained by analyzing multiple cases, and genetic subtypes can be constructed. However, this correspondence is simply to match the above characteristics of the case with the genetic subtype, which is less flexible and cannot guarantee that a representative correspondence can be extracted from it, resulting in the scope of application of the genetic subtype prediction model. narrow

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