Metagenome reassembling method, a metagenome reassembling device and terminal equipment

A technology of metagenomic and assembly methods, applied in the field of bioinformatics, can solve the problems of poor quality of microbial genomes

Pending Publication Date: 2020-05-15
余珂
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The embodiment of the present application provides a metagenomic reassembly method, reassembly device and terminal equipment, which can solve the problem of poor quality of the microbial genome obtained by the existing metagenomic component box method

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  • Metagenome reassembling method, a metagenome reassembling device and terminal equipment
  • Metagenome reassembling method, a metagenome reassembling device and terminal equipment

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[0043] In the following description, for the purpose of illustration rather than limitation, specific details such as a specific system structure and technology are proposed for a thorough understanding of the embodiments of the present application. However, it should be clear to those skilled in the art that the present application can also be implemented in other embodiments without these specific details. In other cases, detailed descriptions of well-known systems, devices, circuits, and methods are omitted to avoid unnecessary details from obstructing the description of this application.

[0044] It should be understood that when used in the specification and appended claims of this application, the term "comprising" indicates the existence of the described features, wholes, steps, operations, elements and / or components, but does not exclude one or more other The existence or addition of features, wholes, steps, operations, elements, components, and / or collections thereof.

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Abstract

The invention belongs to the technical field of biological information, and relates to a metagenome reassembling method, a metagenome reassembling device and terminal equipment. The method comprises the following steps: acquiring an initial genome set after genome assembling processing and metagenome binning processing, wherein the initial genome set comprises a plurality of microbial genomes; extracting a non-redundant genome of each species in the initial genome set, wherein each non-redundant genome is a microbial genome with the largest number of target genes corresponding to the species to which the non-redundant genome belongs; and separately carrying out reassembling treatment on each non-redundant genome to obtain reassembled microbial genomes. By means of the method, the microbialgenomes with high quality can be obtained, and reliable research objects are provided for subsequent gene research.

Description

Technical field [0001] This application belongs to the field of biological information technology, and in particular relates to a metagenomic reassembly method, reassembly device and terminal equipment. Background technique [0002] Metagenomics is the sum of the genetic material of all micro organisms in the environment, including the genes of cultivable and non-cultivable microorganisms. The research method that takes metagenomics as the research object is called metagenomics. This method does not require microbial culture and can directly analyze and study nucleotide sequences taken from environmental samples. [0003] At present, metagenomics includes extracting genomic data (such as nucleotide sequences) in environmental samples, sequencing the extracted genomic data to obtain gene sequencing sequences, performing gene assembly processing on gene sequencing sequences to obtain contigs, and macros to contigs. Gene bin processing to obtain the microbial genome, and conduct gene...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16B20/00G16B30/20
CPCG16B20/00G16B30/20
Inventor 余珂乔雪姣张立羽谢克聪
Owner 余珂
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