Blood glucose signal acquisition device, and blood glucose concentration detection device and system

A signal collection and blood sugar concentration technology, applied in the medical field, can solve problems such as inaccurate blood sugar concentration detection, difficulty in blood sugar detection, Raman signal interference, etc., and achieve the effect of reducing the interference of blood sugar Raman signal changes

Pending Publication Date: 2022-02-25
WUHAN UNITED IMAGING HEALTHCARE SURGICAL TECH CO LTD
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  • Claims
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Problems solved by technology

However, it is still very difficult to apply this method to human blood glucose detection. One of the reasons is that the SERS method is very sensitive to distance. During the measurement process...

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  • Blood glucose signal acquisition device, and blood glucose concentration detection device and system
  • Blood glucose signal acquisition device, and blood glucose concentration detection device and system
  • Blood glucose signal acquisition device, and blood glucose concentration detection device and system

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Embodiment Construction

[0039] In order to make the purpose, technical solution and advantages of the present application clearer, the present application will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present application, and are not intended to limit the present application.

[0040] In one embodiment, as figure 1 As shown, a blood glucose signal acquisition device is proposed, including: a base plate 100, a SERS substrate 200, a pressure sensor 300, and a Raman spectrometer 400; wherein, the base plate 100 is provided with a through hole; the SERS substrate 200 is installed on the base plate 100, And at least part of the SERS substrate 200 is disposed in the through hole portion; the pressure sensor 300 is disposed on the SERS substrate 200 for detecting the pressure on the SERS substrate 200; the Raman spectrometer 400 is disposed on the SERS ...

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Abstract

The invention relates to the field of medicine, and concretely relates to a blood glucose signal acquisition device, and a blood glucose concentration detection device and system. The blood glucose signal acquisition device comprises a bottom plate, an SERS substrate, a pressure sensor and a Raman spectrometer, wherein the bottom plate is provided with a through hole part; the SERS substrate is mounted on the bottom plate, and at least partial area of the SERS substrate is arranged in the through hole part; the pressure sensor is arranged on the SERS substrate or the bottom plate and is used for detecting the pressure borne by the SERS substrate; and the Raman spectrometer is arranged below the SERS substrate. Compared with the prior art, the Raman spectrometer is used for collecting the blood glucose Raman signal through the SERS substrate, the pressure sensor is used for detecting the pressure borne by the SERS substrate, the blood glucose Raman signal and the pressure signal are synthesized to determine the blood glucose concentration, and the interference of blood glucose Raman signal change caused by movement of a measured part is reduced.

Description

technical field [0001] The present application relates to the medical field, in particular to a blood sugar signal collection device, a blood sugar concentration detection device and a detection system. Background technique [0002] Raman spectrometer is very effective for blood glucose concentration detection, but limited by the weak signal of Raman spectrum (usually only 10 of the incident light intensity -6 times), the Raman spectrometer is bulky and inconvenient to carry around. Based on this, the patent US9279759B2 applied the surface-enhanced Raman spectroscopy (SERS) method and used functional nanoparticle SERS substrates to greatly enhance the Raman signal. By using different metal nanostructures, 10 6 ~10 9 The signal enhancement of the Raman spectrometer provides a scalable solution for the miniaturization of the Raman spectrometer. However, it is still very difficult to apply this method to human blood glucose detection. One of the reasons is that the SERS meth...

Claims

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Application Information

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IPC IPC(8): A61B5/1455
CPCA61B5/1455A61B5/14532
Inventor 陈潇
Owner WUHAN UNITED IMAGING HEALTHCARE SURGICAL TECH CO LTD
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