The invention relates to a flexible photonic skin, which comprises a functional layer disposed, a bonding layer composed of hypoallergenic polyvinyl ethyl ether for fixing the functional layer, and anencapsulated layer adhered to the bonding layer and composed of a polyurethane semipermeable film in order from bottom to top, The functional layer consists of two electrodes on both sides for collecting human ECG signals, and a polymer-based photonic integrated chip for collecting body temperature, pulse, blood pressure and blood glucose signals between the two electrodes, and the polymer-basedphotonic integrated chip processes and outputs the collected human ECG signals, human body temperature, pulse, blood pressure and blood glucose signals. The flexible photonic skin has the advantages of anti-electromagnetic interference, small size, light weight, good temperature resistance, strong multiplexing capability, and high sensitivity, and the equivalent modulus is equivalent to the humanskin modulus. The flexible photonic skin can use a Bragg waveguide raster and a MZI electro-optic modulator to continuously monitor physiological information such as body temperature, pulse, blood pressure, blood sugar and electrocardiogram, and improves the portability and comfort of active health monitoring.