233 results about "Blood glucose testing" patented technology

The invention belongs to the technical field of medical health monitoring, and relates to a noninvasive blood glucose detection method based on reinforcement learning and multi-modal dynamic weight fusion, and the method comprises the following steps: carrying out adaptive dynamic weight distribution on the weight of an ECG signal and a PPG signal based on a reinforcement learning network, optimizing a signal processing parameter, and determining whether to trigger threshold adjustment; performing weighted feature fusion on the ECG signal and the PPG signal to obtain a fusion feature vector; the fusion feature vector is input into a prediction and early warning double-branch output structure, the prediction and early warning double-branch output structure comprises a regression branch and a classification branch, the regression branch is used for continuously predicting the blood glucose value, and finally a single blood glucose concentration value is output; and the classification branch is used for early warning level judgment, and finally outputting classification alarms for continuous prediction results so as to complete noninvasive blood glucose detection. The method has the beneficial effects that the fluctuation influence of user movement and temperature on noninvasive blood glucose data acquisition is reduced, and the individual difference suitability and long-term stability of noninvasive blood glucose detection are improved.

The invention provides a full-dynamic non-invasive blood glucose detection method based on a full-spectrum peak segment optimization algorithm. The method comprises the following steps: step S1, performing blood glucose testing on a nail bed part of a human little finger by matching an infrared dual-wavelength semiconductor laser with a spectrograph, and recording blood glucose Raman spectrum data obtained in each blood glucose testing; step S2, carrying out pretreatment on the obtained blood glucose Raman spectrum data; s3, dividing the preprocessed blood glucose Raman spectrum data into a training set and a prediction set, analyzing through a principal component analysis method and a partial least square regression analysis method, and establishing a model; s4, inputting the preprocessed blood glucose Raman spectrum data as an independent variable into the model in the step S3, analyzing the blood glucose concentration of the human body, and giving a reference value; according to the full-dynamic non-invasive blood glucose detection method based on the full-spectrum peak segment optimization algorithm, the accuracy of quantitative analysis of a high-fluorescence background sample through a Raman spectrum is achieved, complex treatment on the sample is not needed, and the accuracy of human body non-invasive blood glucose detection is improved.

The embodiment of the invention provides a detachable detection device and a needle assistor, the detection device is used for detecting blood glucose, the detection device comprises a detection assembly, a sensor assembly and a needling assembly, the detection assembly comprises a flat shell, the outer wall of the bottom of the flat shell is sunken inwards to form a containing cavity, the sensor assembly comprises a base and a probe, the base is provided with a second via hole, and the probe is arranged in the containing cavity. The base is detachably clamped in the containing cavity, part of the probe is located in the base, part of the probe extends out of the hole wall of the second through hole and extends towards the side away from the detection assembly, and when the base is located in the containing cavity, the probe is electrically connected with the detection circuit board. According to the embodiment of the invention, the detection assembly and the sensor assembly are mutually detachable and can be clamped, so that only the sensor assembly is sterilized instead of the detection assembly in the sterilization process, and the influence on the detection circuit board in the detection assembly in the electromagnetic wave or irradiation sterilization process can be avoided; the product yield of the detection device is improved.

The invention discloses a hydrogel microneedle patch for noninvasive blood glucose detection as well as a preparation method and application of the hydrogel microneedle patch. According to the invention, the microneedle patch is prepared by a turnover technology and is noninvasively applied to the skin surface, so that simple and rapid extraction of interstitial fluid in vivo and a new method for real-time, rapid and quantitative detection of blood glucose in vivo are realized. The hydrogel microneedle patch contains two hydrogel components: one hydrogel component is hydrogel which can be cured and formed by ultraviolet light, and the other hydrogel component is hydrogel which can be cured and formed by ultraviolet light; and the other hydrogel is functional hydrogel with pH responsiveness, and glucose oxidase is added, so that the hydrogel can sensitively react to in-vivo glucose. The double-response hydrogel is jointly mixed and prepared into a microneedle patch form, the microneedle patch is endowed with noninvasive / minimally invasive property when applied to the skin surface, the microneedle patch is very suitable for extraction of interstitial fluid in vivo, and then real-time, rapid and accurate detection of the blood glucose level in vivo is achieved.

The invention discloses a glucometer high-precision detection method based on a dynamic calibration algorithm and a glucometer, and relates to the field of blood glucose detection.The method comprises the steps that modal decomposition is conducted on a blood glucose current signal, the blood glucose current signal is decomposed into a plurality of frequency components, and an effective physiological component and an interference component are separated from the frequency components; performing time sequence feature extraction on the effective physiological component to obtain feature parameters at multiple moments, and performing correlation analysis on the feature parameters at the multiple moments, the environment temperature and the tissue impedance parameter to obtain a fusion feature vector; inputting the fusion feature vector into a parameter calibration model, and outputting a preliminary blood glucose value; a temperature correction coefficient is calculated according to the deviation between the environment temperature and the preset reference temperature, the initial blood glucose value is dynamically adjusted according to the temperature correction coefficient, and a final blood glucose detection value is obtained. By implementing the method, the detection accuracy of the glucometer can be improved.

The invention discloses a personalized adoptive non-invasive blood glucose monitoring method, system and device and a medium, and the method comprises the steps: obtaining a blood glucose sample and a physiological parameter sample of a target individual, and calibrating a trained universal artificial intelligence prediction model according to the blood glucose sample and the physiological parameter sample of the target individual, a personalized artificial intelligence prediction model is obtained; the universality artificial intelligence prediction model is obtained by training according to a blood glucose sample and a physiological parameter sample of a group; acquiring physiological parameters of the target individual, and monitoring blood glucose of the target individual according to the physiological parameters of the target individual and the personalized artificial intelligence prediction model; the physiological parameters are obtained through non-creative measurement. The embodiment of the invention can noninvasively, accurately and continuously monitor the blood glucose of the target individual, and can be widely applied to the technical field of blood glucose detection.

The invention relates to the technical field of sensors, in particular to a CIOD-based noninvasive blood glucose detection sensor and method.The sensor comprises a multi-layer structure and comprises a first flexible polyimide substrate tightly attached to the skin, a temperature control assembly, a second flexible polyimide substrate and a glucose detection patch; the temperature control assembly comprises a temperature sensor and a heating wire and is used for thermally activating the skin; the glucose detection patch comprises three electrode areas filled with perfluorinated sulfonic acid resin, wherein the first electrode area comprises a first sodium ion working electrode, a shared electrode and a detection working electrode; the second electrode region contains a sodium ion reference electrode; the third electrode area comprises a second sodium ion working electrode and an auxiliary electrode; the electrodes are connected through insulating coating wires; the shared electrode and the auxiliary electrode form an interstitial fluid extraction electrode pair, and the detection working electrode and the shared electrode form a glucose detector to detect a hydrogen peroxide signal generated by glucose oxidation; the first sodium ion working electrode, the second sodium ion working electrode and the sodium ion reference electrode form a sodium ion differential detector to calibrate a glucose signal. According to the novel noninvasive blood glucose detection sensor provided by the invention, efficient, noninvasive and portable blood glucose monitoring can be realized by combining thermal activation and differential self-calibration.

The invention discloses a rapid detection device for diabetic nephropathy patients, and belongs to the technical field of diabetic nephropathy patient detection.The rapid detection device comprises a blood glucose detection assembly, a self-adaptive adjusting mechanism, an extrusion force adjusting structure and an automatic blood taking mechanism, and the self-adaptive adjusting mechanism is arranged on the blood glucose detection assembly; the extrusion force adjusting structure is arranged in the blood glucose detection assembly, the extrusion force adjusting structure is connected with the self-adaptive adjusting mechanism, the extrusion force adjusting structure comprises an adjusting assembly and a reciprocating displacement assembly, and the automatic blood taking mechanism is arranged on the blood glucose detection assembly. By arranging the self-adaptive adjusting mechanism, the extrusion force adjusting structure and the automatic blood taking structure, the extrusion force for assisting the blood taking structure of the person to be detected is self-adaptively adjusted according to different thicknesses of the hands of the person to be detected, and it is ensured that the device can take out sufficient blood for detection; and tissue fluid groups which influence a detection result can be prevented from existing in blood, so that the detection precision of the device is improved.

The embodiment of the invention provides a manufacturing method of a test paper connector, the test paper connector and a glucometer, and relates to the field of blood glucose detection. The manufacturing method of the test paper connector comprises the following steps: adjusting the height h of the pin of the test paper seat plug-in device to be lower than the height H of the positioning column; mounting a test paper holder plug-in device and a bottom surface component on the PCB; performing reflow soldering on the test paper holder plug-in device and the bottom surface component; and mounting a top surface component on the top surface of the PCB. According to the manufacturing method disclosed by the embodiment of the invention, the sizes of the positioning columns and the pins of the test paper seat plug-in device are adjusted, the pins are prevented from scraping a steel mesh, the test paper seat plug-in device is mounted in the jacks when the components on the bottom surface of the PCB are mounted, and then reflow soldering is performed together, so that the test paper seat plug-in device does not need to be manually post-welded, the operation step of manual welding is omitted, and the production efficiency is improved. One mounting operation procedure is reduced, the production efficiency can be improved, and the production cost is reduced. The embodiment of the invention also provides a test paper connector and a glucometer.

Provided in the present application are a blood glucose monitoring method and a related apparatus. In the method, the blood glucose level at a first moment can be acquired on the basis of a glucose concentration in interstitial fluid at the first moment, a glucose concentration in the interstitial fluid within a time period before the first moment and a glucose concentration in the interstitial fluid within a time period after the first moment. In the present application, the glucose concentration in the interstitial fluid within the time period after the first moment is taken into consideration, and an additional time period is provided for the diffusion of glucose between the interstitial fluid and blood; therefore, when the blood glucose level drastically changes, the glucose concentration in the interstitial fluid more closely approximates the blood glucose level, and thus the accuracy of blood glucose monitoring can be improved.

The invention relates to the technical field of medical apparatus and instruments, and discloses a ring-type noninvasive blood glucose detector capable of continuously monitoring blood glucose, comprising a shell sleeving a finger of a wearer; the signal acquisition part is arranged in a shell cavity of the shell, a gap is formed between the detection end of the signal acquisition part extending out of the inner side wall of the shell and the detection part, and the signal acquisition part is used for acquiring biological sign parameters and environmental characteristic parameters of the wearer; the limiting and fixing part is arranged on the shell, the limiting and fixing part and the shell form an annular structure, and the perimeter size of the inner side of the annular structure is adjusted through the limiting and fixing part; the transmission part is arranged in the shell, the biological sign parameters and the environment characteristic parameters of the wearer are calculated through the calculation module, and the calculated result is transmitted to mobile equipment of the wearer through the transmission part. The non-invasive blood glucose detection device realizes non-invasive blood glucose detection, avoids injury to users, is convenient to adjust, adapts to different users, and improves the measurement precision.

The invention relates to the technical field of intelligent diabetes treatment instruments, in particular to a closed-loop non-invasive insulin detection and precise infusion system which is characterized by comprising a blood glucose monitoring regulator, a non-invasive injector and a closed-loop control mechanism. The closed-loop control mechanism comprises a real-time blood glucose detection module, a temperature detection module, a blood glucose data processing module, a dose decision module, an injection pressure adjusting module, an injection channel control module, an insulin injection module and a closed-loop feedback module; noninvasive and high-sensitivity real-time blood glucose monitoring is achieved, the accuracy and timeliness of insulin administration are improved through trend prediction and individualized dose decision, meanwhile, multi-nozzle array piezoelectric needleless injection is combined with temperature compensation pressure regulation and a closed loop feedback correction mechanism, local tissue burden is effectively reduced, and the insulin administration efficiency is improved. And through multiple safety protection and wireless data transmission, remote monitoring and intelligent management are realized, so that the convenience, accuracy and reliability of blood glucose management of diabetic patients are greatly improved.

The invention discloses a blood glucose detection method based on a nucleic acid aptamer. The blood glucose detection method comprises the following steps: S1, constructing a compound; s2, realizing fluorescence signal change; s3, quantitatively analyzing the glucose concentration. The invention relates to the technical field of biological detection, in particular to a blood glucose detection method based on an aptamer, which has the following advantages: 1, high stability and low cost; 2, high specificity; 3, multifunctionality and expansibility are realized; and 4, determining a wide detection range and a linear relation.

The invention discloses a glucose detection device for synchronously collecting and analyzing sweat interstitial fluid and a manufacturing method, and belongs to the technical field of sensors. In the device, a sweat discharge module and an interstitial fluid discharge module are embedded and fixed in a supporting layer; the sealing layer, the body fluid storage layer and the flow guide layer jointly define a sweat storage cavity and an interstitial fluid storage cavity which are distributed at intervals, and a sweat pH sensing module and an interstitial fluid pH sensing module are fixed to the sealing layer; the flow guide layer, the microfluidic layer and the detection layer jointly define a sweat microfluidic detection cavity and an interstitial fluid microfluidic detection cavity, a sweat temperature sensing module and an interstitial fluid temperature sensing module are fixed on the flow guide layer, and a sweat glucose sensing module and an interstitial fluid glucose sensing module are fixed on the detection layer; a sweat collection module and an interstitial fluid collection module are embedded in the detection layer and the skin adhesion layer. The non-invasive, high-precision and continuous blood glucose detection is realized, the processing is convenient, the processing efficiency is high, and the cost is low.

The utility model relates to the technical field of blood glucose detection auxiliary devices, and discloses a blood glucose detection disc for clinical nursing of the endocrinology department, which comprises a tray, a storage drawer is arranged at the front end in the tray, and limiting structures for conveniently limiting the storage drawer and a cleaning drawer are arranged at the front end and the rear end of two sides of the tray. According to the blood glucose detection disc for clinical nursing of the endocrinology department, by arranging a connecting plate, a supporting rod, a limiting rod, a fixing block, a spring and a limiting sliding groove, when a storage drawer and a cleaning drawer need to be limited and fixed, the supporting rod is rotated downwards, so that the connecting plate is not fixed; the springs enable the limiting rods to rebound to the two sides of one ends of the storage drawer and the cleaning drawer through the elasticity of the springs, so that the storage drawer and the cleaning drawer can be limited and fixed, the storage drawer and the cleaning drawer are prevented from sliding accidentally, and the problem that the drawers for containing materials and tools are inconvenient to limit and fix is solved. And the drawer is easy to open accidentally.

1. Name of the product in this design: Blood glucose meter. 2. Purpose of this design: For blood glucose testing. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

1. The name of the design product: blood glucose meter. 2. The use of the design product: the product is used with blood glucose test strips to measure and display blood glucose information. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The invention provides a food measuring device based on gestational diabetes mellitus of a pregnant woman, and relates to the technical field of diabetes mellitus medical equipment. Comprising a nutrition control mechanism and a blood sugar monitoring mechanism, and the nutrition control mechanism and the blood sugar monitoring mechanism are detachably connected; the nutrition control mechanism comprises a base, a limiting groove is formed in the base, a placement disc is arranged on the limiting groove, and a pressure sensor is arranged between the placement disc and the limiting groove; a telescopic rod is arranged on the base, and a camera is arranged on the telescopic rod; the blood glucose monitoring mechanism comprises a wearing main body, a blood glucose detector, a controller and a display screen are arranged on the wearing main body, and the controller is electrically connected with the blood glucose detector and the display screen; compared with the prior art, the device is simple in structure, convenient to use and carry and capable of effectively monitoring and controlling diet nutrition of the pregnant woman.

The embodiment of the invention provides printing ink for blood glucose test paper as well as a preparation method and application thereof, and belongs to the technical field of printing ink. The printing ink comprises the following components in parts by weight: 40-70 parts of thermoplastic acrylic resin; 30 to 50 parts of hydroxy acrylic resin; 20-30 parts of an organic solvent; 3-5 parts of a dispersant; 50 to 70 parts of titanium dioxide; 10 to 20 parts of filler; 0.5 to 2 parts of a defoaming agent; 0.5 to 2 parts of a drier; 5-10 parts of a cross-linking agent; the glass transition temperature Tg of the thermoplastic acrylic resin is 45-85 DEG C, the hydroxyl value of the hydroxy acrylic resin is 35-85 mg KOH / g, and the thermoplastic acrylic resin and the hydroxy acrylic resin form a compact three-dimensional network molecular chain structure under the action of the cross-linking agent. The printing ink provided by the invention has good biocompatibility and uniform film thickness, stably protects the isolation layer, and improves the performance of the test paper.

The utility model provides a blood glucose detector, which solves the problem that the existing blood glucose detector with a single cavity structure cannot meet the modern daily small and portable requirements and the like, and adopts the main scheme that the blood glucose detector comprises a first shell and a second shell, the top surface of the first shell is concavely provided with a first space, and an integrated special-shaped plate is fixed on one side of the top surface of the first shell; the special-shaped plate comprises at least one flange, the flange is smoothly connected with the outer edge of the top face of the first shell, the outer edge of the bottom face of the second shell and the flange and the outer edge of the flange connected with the top face of the first shell are magnetically attracted and fixed into a whole, the interior of the second shell is hollowed out, and the bottom face of the second shell is sealed through an assembly plate to form a second space. The first space is used for containing a needle head and test paper, a PCB and a display screen electrically connected with the PCB are arranged in the second space, and an insertion opening is formed in one side of the assembly plate so that the test paper can be inserted into the insertion opening to react with the PCB.

The application discloses a blood glucose detection test paper production equipment and relates to the field of test paper production, which comprises a processing table, a support is fixedly connected to the upper end face of the processing table close to the front side, a movable plate is slidably inserted into the support, three cutting knives are fixedly connected to the lower end face of the movable plate at equal intervals, and three discharge ports are formed in the upper end face of the processing table corresponding to the cutting knives. The two servo motors can drive the movable plate to reciprocate up and down in the support, thereby driving the cutting knives to cut the test paper sent to the discharge port. In the process of ascending of the movable plate, the upper ends of the two rotating plates are pushed away from each other by the push plate, thereby driving the two shovel plates to open. When the movable plate descends, the lower ends of the two rotating plates are driven away from each other by the push plate, thereby driving the two shovel plates to be attached to the front and back sides of the cutting knives, so that the glue adhered to the cutting knives is scraped off by the shovel plates in the process of continuous descending of the cutting knives, the sharpness of the cutting knives is ensured, and the cutting knives can smoothly cut the test paper.

1. Name of the product in this design: Biosensor Electrode Device. 2. Purpose of this design: For continuous blood glucose monitoring via partial implantation in subcutaneous tissue. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

A purification method for an electron mediator on a biosensor, the electron mediator having an amino. The purification method comprises the following steps: weighing an electron mediator with low purity; reacting an amino protection reagent with the electron mediator to obtain an amino-protected electron mediator, dissolving the amino-protected electron mediator in an organic solvent, and carrying out extraction to obtain an amino-protected electron mediator with high purity; and reacting the amino-protected electron mediator with high purity with a deprotection reagent for amino deprotection, thus obtaining an electron mediator with high purity. The method for purification achieves a very large treatment capacity in one time, effectively improves the purification efficiency of the electron mediator, and reduces the preparation cost. The electron mediator with high purity obtained from purification, serving as one of the components in the reagent on a biosensor, can be used for preparation of biosensors such as a blood glucose test biosensor.

The application discloses an integrated automatic blood-squeezing peripheral blood glucose detection device, which comprises a host computer (1) and a detachably connected disposable sterile integrated core (2). The disposable sterile integrated core (2) comprises a microneedle assembly (4), an elastic squeezing structure (3) arranged around the microneedle assembly (4), a blood glucose detection test paper (6), a capillary blood guiding channel (5) and an electrode contact (7). When the microneedle assembly (4) completes skin puncture, the elastic squeezing structure (3) applies synchronous micro mechanical squeezing force to the tissue around the blood sampling site, so that blood seeps out and is automatically transported to the blood glucose detection test paper (6) through the capillary blood guiding channel (5). The blood glucose detection test paper (6) is internally integrated in the disposable sterile integrated core (2), and the electrode contact (7) is used for electrical connection with the host computer (1). The application realizes the integration of blood sampling, automatic blood squeezing, blood guiding and detection by using a pure mechanical structure, and does not need manual blood squeezing and manual sample adding. The application has the advantages of simple structure, low cost, simple operation, safety and sanitation, and is suitable for rapid blood glucose detection in family and hospital scenes.

The present invention comprises: a case forming an accommodation space in which a plurality of blood glucose test strips can be accommodated; a moving-up / down plate which is provided in the accommodation space of the case so as to be movable up and down, and on which the blood glucose test strips arranged in the horizontal direction are stacked in the vertical direction; a cap which forms a sliding space in which the uppermost blood glucose test strip, from among the plurality of blood glucose test strips placed on the moving-up / down plate, can be arranged, and is provided on the upper end of the case; a sliding button which is slidably provided on the cap, and which presses one longitudinal end of the blood glucose test strip arranged in the sliding space, to slide the blood glucose test strip; and a withdrawal port which is formed in the cap and guides, to the outside of the case, the blood glucose test strip moved by the sliding button.

The present application belongs to the technical field of medical health monitoring, and relates to a non-invasive blood glucose detection method based on reinforcement learning and multi-modal dynamic weight fusion. The method comprises: based on a reinforcement learning network, performing adaptive dynamic weight distribution on the weights of ECG signals and PPG signals, optimizing signal processing parameters, and confirming whether a threshold value is triggered for adjustment; performing weighted feature fusion on the ECG signals and PPG signals to obtain a fusion feature vector; inputting the fusion feature vector into a prediction and early warning double-branch output structure, wherein the prediction and early warning double-branch output structure comprises a regression branch and a classification branch, the regression branch is used for continuous prediction of blood glucose values, and finally outputs a single blood glucose concentration value; the classification branch is used for early warning level determination, and finally outputs a graded alarm for the continuous prediction result, so as to complete non-invasive blood glucose detection. The beneficial effects are that the fluctuation influence of user motion and temperature on non-invasive blood glucose data acquisition is reduced, and the individual difference adaptability and long-term stability of non-invasive blood glucose detection are improved.

The embodiment of the application provides a printing ink for blood glucose test paper, a preparation method and application thereof, and belongs to the technical field of printing ink.The printing ink comprises, by weight parts, 40-70 parts of thermoplastic acrylic resin, 30-50 parts of hydroxyl acrylic resin, 20-30 parts of organic solvent, 3-5 parts of dispersing agent, 50-70 parts of titanium white, 10-20 parts of filler, 0.5-2 parts of defoaming agent, 0.5-2 parts of drying agent, 5-10 parts of crosslinking agent, the glass transition temperature Tg of the thermoplastic acrylic resin is 45-85 DEG C, the hydroxyl value of the hydroxyl acrylic resin is 35-85 mg KOH / g, and the two form a dense three-dimensional network molecular chain structure under the action of the crosslinking agent.The printing ink has good biological compatibility and uniform film thickness, stably protects an isolation layer, and improves the performance of the test paper.

The application discloses a medical blood glucose test paper strip cutting and packaging production line and a process thereof, which comprises a material bucket vibration feeding module, a material bucket conveying line used for equidistantly conveying material buckets, a material bucket carrying mechanism, a test paper strip cutting and barrel filling mechanism, a CCD camera module, a weighing and distributing mechanism, a pressing and detecting mechanism, a barrel cap vibration feeding module and a barrel cap carrying mechanism.

The present application relates to the technical field of pattern recognition, in particular to a blood glucose detection region selection method based on blood perfusion imaging, comprising collecting continuous laser speckle original images of a to-be-detected skin region and a peripheral pulse wave signal of a subject, and constructing a bottom layer data matrix. The image sequence is converted into a perfusion contrast evolution sequence by calculating the ratio of the standard discrete degree and the average brightness of the pixel intensity in the three-dimensional data block. Frequency locking operation is performed using the main frequency of the pulse wave to separate out the perfusion fluctuation component synchronized with the heart beat rhythm, and the phase lag distribution map of each pixel point is determined through cross-correlation time delay analysis. The tissue damping coefficient of each pixel point is obtained by combining the tissue viscoelasticity kinetic damping model inversion, and the pixel set in the target response interval is screened and clustered according to the mapping relationship between the blood glucose concentration and the damping coefficient to determine the blood glucose detection target region. The present application realizes the locking of the detection region through tissue damping characteristic inversion and clustering screening.

The invention relates to the technical field of blood glucose detection, and particularly discloses a blood glucose monitoring method based on the content of glucose in saliva, which comprises the following steps: contacting a pretreated sample with a monitoring system, and connecting with an electrochemical workstation through the monitoring system, setting the working potential of the monitoring system through an electrochemical workstation, collecting the electric signal change of the monitoring system, and calculating the glucose content in the saliva according to the electric signal change so as to deduce the blood glucose level; and the monitoring system comprises a Ni5P4-FeP / Ti electrocatalyst. By adopting the technical scheme, the saliva pH environment can be met, the detection limit and precision meet the accurate glucose detection requirement, and the detection operation is simple.