324 results about "Blood glucose testing" patented technology

The invention discloses a method for evaluating postprandial blood glucose response of a human body based on continuous blood glucose data and application. The method comprises the following steps: acquiring a continuous blood glucose detection value and meal starting time; matching a first blood glucose recording point after eating according to the dining time, intercepting blood glucose data of 2 hours after meal, and preprocessing the data; constructing four postprandial blood glucose response modes by applying the continuous blood glucose data of FPCA and based on a characteristic function of which the interpretation degree ranks top two obtained by the FPCA; through comparison of postprandial blood glucose response mean value curves of the four blood glucose response modes, the four response modes can evaluate postprandial blood glucose by integrating the blood glucose concentration range and whether the fasting homeostasis can be rapidly recovered or not.

The invention belongs to the technical field of medical health monitoring, and relates to a noninvasive blood glucose detection method based on reinforcement learning and multi-modal dynamic weight fusion, and the method comprises the following steps: carrying out adaptive dynamic weight distribution on the weight of an ECG signal and a PPG signal based on a reinforcement learning network, optimizing a signal processing parameter, and determining whether to trigger threshold adjustment; performing weighted feature fusion on the ECG signal and the PPG signal to obtain a fusion feature vector; the fusion feature vector is input into a prediction and early warning double-branch output structure, the prediction and early warning double-branch output structure comprises a regression branch and a classification branch, the regression branch is used for continuously predicting the blood glucose value, and finally a single blood glucose concentration value is output; and the classification branch is used for early warning level judgment, and finally outputting classification alarms for continuous prediction results so as to complete noninvasive blood glucose detection. The method has the beneficial effects that the fluctuation influence of user movement and temperature on noninvasive blood glucose data acquisition is reduced, and the individual difference suitability and long-term stability of noninvasive blood glucose detection are improved.

The invention discloses a multichannel blood sample shunt detection glucometer, and belongs to the technical field of glucometers, the multichannel blood sample shunt detection glucometer comprises a base, the top side in the base is fixedly connected with a protective cover, the bottom side in the protective cover is provided with a detection disc, and the bottom side in the detection disc is provided with a mounting groove. According to the device, a driving motor drives a detection disc, a connecting shaft and a gear to rotate, the gear drives the connecting shaft, an annular block and an arc-shaped convex block to rotate under the action of a fan-shaped fluted disc, and the arc-shaped convex block can extrude a roller, a connecting rod and a second spring in the rotating process; a plurality of rollers intermittently drive a connecting rod, a spherical hinge support and a spherical hinge support to move upwards, that is, a fixed seat continuously drives a blood sample storage transparent tube to perform shaking, vibration and static settlement treatment, so that blood and a reagent in the blood sample storage transparent tube are fully mixed and reacted; therefore, the subsequent blood glucose detection precision of the equipment on the blood in the blood sample storage transparent tube is ensured.

The invention discloses a real-time adjusting method for insulin infusion volume, which adopts a closed-loop control method, and dynamically adjusts the infusion volume of an insulin pump based on a comparison result of a predicted blood glucose parameter and a preset blood glucose range through collected blood glucose data and predicted future blood glucose data, thereby realizing more accurate blood glucose control. The invention further discloses a closed-loop infusion system designed based on the real-time adjustment method. The closed-loop infusion system comprises a controller, a blood glucose detection system, an insulin pump and a continuous glucose monitoring system. Compared with open-loop control, the closed-loop control can monitor the blood glucose level of the patient in real time and automatically adjust the insulin infusion amount according to real-time data, and the high-automation system can more accurately maintain the blood glucose within the target range and reduce blood glucose fluctuation. Moreover, the closed-loop control system reduces the requirements of patients or medical staff for manually calculating and adjusting the insulin dosage, so that personal errors are reduced, automatic adjustment can better adapt to individual differences and dynamic changes of the patients, the burden of the patients on blood glucose monitoring and insulin dosage adjustment is reduced, and the safety and effectiveness of treatment are improved.

The invention provides a power management and power consumption control device and method of a continuous blood glucose detection circuit. Relates to the technical field of continuous blood glucose detection, solves the problems of power consumption control and switching in the prior art, and is characterized in that a power input end of a charge pump is connected with an anode of an external power supply; the control input end of the charge pump is connected with a mode control signal end; the power output end of the charge pump is connected with the first control end of the power switch device; the switching signal control end of the charge pump is connected with the second control end of the power switching device through the delayer; the output end of the power switch device is connected with the working voltage input end, and the working voltage output end is connected with the grounding capacitor; the power output end of the charge pump is connected with the input end of the power-on reset module, the power switch switching signal end of the power-on reset module is connected with the power switch switching signal end of the charge pump, and different working modes can be achieved, so that power consumption control is achieved.

The present invention discloses a non-invasive blood glucose testing method based on a group big data model, which relates to the technical field of blood glucose testing, and includes the following steps: using a near-infrared spectrometer to detect spectral data in skin and tissues, and obtaining the absorption peak of glucose molecules in the near-infrared range; performing preliminary feature extraction on the obtained absorption peak, and after performing abnormal analysis on the extracted features, preliminarily judging whether the absorption peak is abnormal, and screening out the abnormal absorption peak. The present invention uses a machine learning model to screen out abnormal absorption peaks through feature extraction and abnormal analysis, ensures the use of normal data, improves the accuracy of blood glucose prediction, reduces the risk of overestimation or underestimation, provides reliable monitoring for diabetic patients, adjusts drugs in time, and reduces the risk of complications. At the same time, differential analysis and standardized deviation calculation screen out abnormal prediction values, optimize data processing, improve system robustness and final prediction accuracy, and provide accurate non-invasive blood glucose monitoring solutions.

The invention provides a full-dynamic non-invasive blood glucose detection method based on a full-spectrum peak segment optimization algorithm. The method comprises the following steps: step S1, performing blood glucose testing on a nail bed part of a human little finger by matching an infrared dual-wavelength semiconductor laser with a spectrograph, and recording blood glucose Raman spectrum data obtained in each blood glucose testing; step S2, carrying out pretreatment on the obtained blood glucose Raman spectrum data; s3, dividing the preprocessed blood glucose Raman spectrum data into a training set and a prediction set, analyzing through a principal component analysis method and a partial least square regression analysis method, and establishing a model; s4, inputting the preprocessed blood glucose Raman spectrum data as an independent variable into the model in the step S3, analyzing the blood glucose concentration of the human body, and giving a reference value; according to the full-dynamic non-invasive blood glucose detection method based on the full-spectrum peak segment optimization algorithm, the accuracy of quantitative analysis of a high-fluorescence background sample through a Raman spectrum is achieved, complex treatment on the sample is not needed, and the accuracy of human body non-invasive blood glucose detection is improved.

The embodiment of the invention provides a detachable detection device and a needle assistor, the detection device is used for detecting blood glucose, the detection device comprises a detection assembly, a sensor assembly and a needling assembly, the detection assembly comprises a flat shell, the outer wall of the bottom of the flat shell is sunken inwards to form a containing cavity, the sensor assembly comprises a base and a probe, the base is provided with a second via hole, and the probe is arranged in the containing cavity. The base is detachably clamped in the containing cavity, part of the probe is located in the base, part of the probe extends out of the hole wall of the second through hole and extends towards the side away from the detection assembly, and when the base is located in the containing cavity, the probe is electrically connected with the detection circuit board. According to the embodiment of the invention, the detection assembly and the sensor assembly are mutually detachable and can be clamped, so that only the sensor assembly is sterilized instead of the detection assembly in the sterilization process, and the influence on the detection circuit board in the detection assembly in the electromagnetic wave or irradiation sterilization process can be avoided; the product yield of the detection device is improved.

The invention discloses a hydrogel microneedle patch for noninvasive blood glucose detection as well as a preparation method and application of the hydrogel microneedle patch. According to the invention, the microneedle patch is prepared by a turnover technology and is noninvasively applied to the skin surface, so that simple and rapid extraction of interstitial fluid in vivo and a new method for real-time, rapid and quantitative detection of blood glucose in vivo are realized. The hydrogel microneedle patch contains two hydrogel components: one hydrogel component is hydrogel which can be cured and formed by ultraviolet light, and the other hydrogel component is hydrogel which can be cured and formed by ultraviolet light; and the other hydrogel is functional hydrogel with pH responsiveness, and glucose oxidase is added, so that the hydrogel can sensitively react to in-vivo glucose. The double-response hydrogel is jointly mixed and prepared into a microneedle patch form, the microneedle patch is endowed with noninvasive / minimally invasive property when applied to the skin surface, the microneedle patch is very suitable for extraction of interstitial fluid in vivo, and then real-time, rapid and accurate detection of the blood glucose level in vivo is achieved.

The invention relates to the technical field of biomedical detection equipment, and provides a small noninvasive blood glucose detection system and method based on frequency shift and amplitude constraint, the small noninvasive blood glucose detection system and method based on frequency shift and amplitude constraint comprises a field programmable gate array (FPGA), a digital-to-analog converter (DAC) and a voltage-controlled oscillator (VCO), the system comprises a double-frequency complementary split-ring resonator (CSRR) sensor, a detector, an analog-to-digital converter (ADC), a liquid crystal display (LCD), a nixie tube and a power supply module for supplying power, after frequency sweeping is completed, the detector output voltage data stored in the RAM is converted into a power value through calculation, the amplitude of the transmission coefficient of the sensor is obtained according to an S21 parameter formula, and the FGPA controls a nixie tube to display the resonant frequency and the resonant depth of the sensor according to a key. The method is mainly applied to design and manufacturing occasions of medical equipment.

According to the intelligent real-time blood detection system based on the intravascular indwelling sensors, through an intravascular indwelling multi-sensor integrated system (electrochemical / optical coaxial layered design), continuous monitoring of one-time puncture for more than or equal to 7 days is achieved, in a clinical test, puncture within 7 days can be reduced from 28 times to 3 times, an improved Kalman filtering algorithm eliminates signal crosstalk, and the detection accuracy is improved. The D-S evidence theory is combined to dynamically fuse multi-modal data, so that the blood glucose detection MARD is reduced to 4.1%, the blood potassium error is less than 0.08 mM, and the motion artifact residual error is 1t; and 0.5%. A real-time data transmission and intelligent alarm system significantly improves clinical response efficiency, self-adaptively calibrates individual differences, and realizes high-precision long-acting monitoring.

The utility model provides blood glucose detection test paper and a blood glucose detection test paper storage box, and relates to the technical field of blood glucose detection consumables, the blood glucose detection test paper comprises a substrate, an electrode layer is laid on the substrate, and a mistake-proof slot is formed in the lower part of the substrate; an insulating layer is arranged above the electrode layer, a sampling window is formed in the insulating layer, an enzyme layer and a hydrophilic layer are arranged in the sampling window, the enzyme layer is attached to the upper surface of the electrode layer, and the hydrophilic layer is arranged above the electrode layer; a release film is laid on the insulating layer, the release film is divided into a sampling end, a main body and an electrode end through an easy-to-tear line, and the divided release film covers the sampling window, the insulating layer main body and the electrode end respectively. The sealing structure has the advantages of good sealing performance and capability of avoiding wrong insertion of front and back surfaces of electrode ends.

The invention discloses a glucometer high-precision detection method based on a dynamic calibration algorithm and a glucometer, and relates to the field of blood glucose detection.The method comprises the steps that modal decomposition is conducted on a blood glucose current signal, the blood glucose current signal is decomposed into a plurality of frequency components, and an effective physiological component and an interference component are separated from the frequency components; performing time sequence feature extraction on the effective physiological component to obtain feature parameters at multiple moments, and performing correlation analysis on the feature parameters at the multiple moments, the environment temperature and the tissue impedance parameter to obtain a fusion feature vector; inputting the fusion feature vector into a parameter calibration model, and outputting a preliminary blood glucose value; a temperature correction coefficient is calculated according to the deviation between the environment temperature and the preset reference temperature, the initial blood glucose value is dynamically adjusted according to the temperature correction coefficient, and a final blood glucose detection value is obtained. By implementing the method, the detection accuracy of the glucometer can be improved.

The invention discloses a personalized adoptive non-invasive blood glucose monitoring method, system and device and a medium, and the method comprises the steps: obtaining a blood glucose sample and a physiological parameter sample of a target individual, and calibrating a trained universal artificial intelligence prediction model according to the blood glucose sample and the physiological parameter sample of the target individual, a personalized artificial intelligence prediction model is obtained; the universality artificial intelligence prediction model is obtained by training according to a blood glucose sample and a physiological parameter sample of a group; acquiring physiological parameters of the target individual, and monitoring blood glucose of the target individual according to the physiological parameters of the target individual and the personalized artificial intelligence prediction model; the physiological parameters are obtained through non-creative measurement. The embodiment of the invention can noninvasively, accurately and continuously monitor the blood glucose of the target individual, and can be widely applied to the technical field of blood glucose detection.

The invention relates to the technical field of sensors, in particular to a CIOD-based noninvasive blood glucose detection sensor and method.The sensor comprises a multi-layer structure and comprises a first flexible polyimide substrate tightly attached to the skin, a temperature control assembly, a second flexible polyimide substrate and a glucose detection patch; the temperature control assembly comprises a temperature sensor and a heating wire and is used for thermally activating the skin; the glucose detection patch comprises three electrode areas filled with perfluorinated sulfonic acid resin, wherein the first electrode area comprises a first sodium ion working electrode, a shared electrode and a detection working electrode; the second electrode region contains a sodium ion reference electrode; the third electrode area comprises a second sodium ion working electrode and an auxiliary electrode; the electrodes are connected through insulating coating wires; the shared electrode and the auxiliary electrode form an interstitial fluid extraction electrode pair, and the detection working electrode and the shared electrode form a glucose detector to detect a hydrogen peroxide signal generated by glucose oxidation; the first sodium ion working electrode, the second sodium ion working electrode and the sodium ion reference electrode form a sodium ion differential detector to calibrate a glucose signal. According to the novel noninvasive blood glucose detection sensor provided by the invention, efficient, noninvasive and portable blood glucose monitoring can be realized by combining thermal activation and differential self-calibration.

The invention discloses a rapid detection device for diabetic nephropathy patients, and belongs to the technical field of diabetic nephropathy patient detection.The rapid detection device comprises a blood glucose detection assembly, a self-adaptive adjusting mechanism, an extrusion force adjusting structure and an automatic blood taking mechanism, and the self-adaptive adjusting mechanism is arranged on the blood glucose detection assembly; the extrusion force adjusting structure is arranged in the blood glucose detection assembly, the extrusion force adjusting structure is connected with the self-adaptive adjusting mechanism, the extrusion force adjusting structure comprises an adjusting assembly and a reciprocating displacement assembly, and the automatic blood taking mechanism is arranged on the blood glucose detection assembly. By arranging the self-adaptive adjusting mechanism, the extrusion force adjusting structure and the automatic blood taking structure, the extrusion force for assisting the blood taking structure of the person to be detected is self-adaptively adjusted according to different thicknesses of the hands of the person to be detected, and it is ensured that the device can take out sufficient blood for detection; and tissue fluid groups which influence a detection result can be prevented from existing in blood, so that the detection precision of the device is improved.

The invention belongs to the field of blood glucose test strip storage boxes, and provides a sealed pressing type blood glucose test strip cross contamination prevention storage box which comprises a sealing box, a paper outlet groove is formed in the upper side of the sealing box, a paper storage box is slidably arranged in the sealing box, a test strip body is arranged on the inner bottom wall of the paper storage box, and a fixing box is fixedly installed on the side wall of the sealing box. A top plate is rotationally arranged in the sealing box, one end of the top plate is in contact with the lower surface of the paper storage box, the other end of the top plate extends into the fixing box, a button is fixedly mounted on the upper surface of the top plate, and a channel is formed in the side wall, connected with the storage box, of the fixing box; non-contact taking of blood glucose test paper is achieved through the pressing type paper outlet mechanism, and cross contamination caused by the fact that fingers make direct contact with a test paper detection area is effectively avoided; by adopting inclined block guiding, extrusion wheel limiting and elastic resetting structures, the test paper is ensured to be uniformly stressed and stably sent out in the taking process, the test paper is prevented from being damaged due to friction or extrusion, and the accuracy and reliability of blood glucose detection are remarkably improved.

A test paper for detecting blood glucose, the test paper comprising a substrate layer (10), an electrode layer, a reagent layer and a covering layer, which are sequentially arranged. The reagent layer comprises 2-3 parts of FAD-GDH, 3-5 parts of a high polymer, 2-3 parts of an electronic medium, 0.2-1 part of a surfactant and 1-2 parts of a buffer solution, wherein the high polymer comprises a first polymer having a degree of polymerization of 200-400 and a second polymer having a degree of polymerization of 200-300. The method for preparing the test paper for detecting blood glucose comprises sputtering a metal layer on the substrate layer (10), etching the electrode layer on the metal layer, dropwise adding a reaction liquid in a reaction area of the electrode layer, drying the reaction liquid to obtain the reagent layer, and pasting the covering layer on the electrode layer, which avoids the problems of instability and low accuracy caused by "coffee-ring" effect.

The invention discloses a preparation method of an SERS (Surface Enhanced Raman Scattering) sensing microneedle patch and application of the SERS sensing microneedle patch in detection of trace blood sugar, and belongs to the technical field of material synthesis and biosensing. According to the preparation method of the SERS sensing microneedle patch disclosed by the invention, a surface enhanced Raman spectroscopy technology and a microneedle patch technology are integrated, a designed SERS probe takes urchin-shaped gold nanoparticles as a core, and a typical core-shell structure is formed through layer-by-layer self-assembly of polydopamine and gradual re-reduction of the gold nanoparticles; the Raman scattering signal is obviously enhanced. The upper layer of the double-layer structure microneedle is hyaluronic acid wrapping glucose oxidase, and the lower layer of the double-layer structure microneedle is methacryloyl hyaluronic acid wrapping an SERS probe. After glucose of interstitial fluid is collected by the microneedle, Raman spectrum characteristic fingerprint change of the SERS probe is caused through catalysis of glucose oxidase, non-invasive, rapid and high-sensitivity blood glucose detection is achieved, and the method is a more comfortable and convenient self-monitoring method.

The embodiment of the invention discloses a noninvasive blood glucose detection system. The system comprises an optical transceiver assembly; the filtering unit is electrically connected with the optical transceiver assembly; the micro-processing unit is electrically connected with the filtering unit; wherein the optical transceiver assembly comprises at least two light sources, a first detector and at least two second detectors, the at least two light sources are used for emitting laser detection signals, and the first detector and the at least two second detectors are used for detecting returned laser signals; the at least two light sources are arranged around the first detector; the at least two second detectors are arranged around the light source; the light detection surface of the first detector, the light detection surfaces of the at least two second detectors and the light emitting surfaces of the at least two light sources face the same direction. According to the application, the short-optical-path optical signal and the long-optical-path optical signal are used for data analysis and processing to obtain the optical concentration difference between the deep part and the superficial part of the skin, so that the influence of melanin and the skin is reduced, and the detection precision of noninvasive blood glucose is improved.

The utility model discloses a fixing adhesive tape for dynamic blood glucose detection, which comprises a non-woven fabric adhesive tape, two pieces of release paper which are respectively first release paper and second release paper, and a protective film which is adhered to the non-adhesive surface of the non-woven fabric adhesive tape, and the protective film is adhered to the non-adhesive surface of the non-woven fabric adhesive tape. The first release paper and the second release paper are folded along the center lines of the first release paper and the second release paper, one half of the first release paper is attached to one half of the glued surface in the non-woven fabric adhesive tape, and one half of the second release paper is attached to the other half of the glued surface in the non-woven fabric adhesive tape; one half of the first release paper is in butt joint with one half of the second release paper and completely covers the gluing face in the non-woven fabric adhesive tape, and the other half of the first release paper is in butt joint with the other half of the second release paper in an attached mode, protrudes out of the non-woven fabric adhesive tape and is not connected with the non-woven fabric adhesive tape. The first release paper and the second release paper can be torn off more easily, the non-woven fabric adhesive tape cannot be wrinkled, the quality of the non-woven fabric adhesive tape is guaranteed, and it can be guaranteed that detection equipment is stably located on the skin of the human body.

The utility model discloses a temperature self-correcting implantable blood glucose sensor. The sensor mainly comprises a bin body, a power supply, a main board, a blood glucose processing module, a temperature correcting module, a Bluetooth receiving and transmitting module and a sensor probe module. The sensor probe module comprises a temperature detection electrode and a blood glucose detection electrode. Wherein the temperature detection electrode is an integrated electrode based on a thermistor, is attached to the surface of the blood glucose detection electrode and is used for detecting and sensing the real-time temperature of an implantation part, and the temperature change is fed back to the blood glucose detection module for correction, so that the measurement accuracy is improved. The device has the advantages of simple structure, high measurement accuracy, no environmental influence and the like, and is suitable for improving the long-term working stability of implantable blood glucose measurement equipment and the like.

The embodiment of the invention provides a manufacturing method of a test paper connector, the test paper connector and a glucometer, and relates to the field of blood glucose detection. The manufacturing method of the test paper connector comprises the following steps: adjusting the height h of the pin of the test paper seat plug-in device to be lower than the height H of the positioning column; mounting a test paper holder plug-in device and a bottom surface component on the PCB; performing reflow soldering on the test paper holder plug-in device and the bottom surface component; and mounting a top surface component on the top surface of the PCB. According to the manufacturing method disclosed by the embodiment of the invention, the sizes of the positioning columns and the pins of the test paper seat plug-in device are adjusted, the pins are prevented from scraping a steel mesh, the test paper seat plug-in device is mounted in the jacks when the components on the bottom surface of the PCB are mounted, and then reflow soldering is performed together, so that the test paper seat plug-in device does not need to be manually post-welded, the operation step of manual welding is omitted, and the production efficiency is improved. One mounting operation procedure is reduced, the production efficiency can be improved, and the production cost is reduced. The embodiment of the invention also provides a test paper connector and a glucometer.

Provided in the present application are a blood glucose monitoring method and a related apparatus. In the method, the blood glucose level at a first moment can be acquired on the basis of a glucose concentration in interstitial fluid at the first moment, a glucose concentration in the interstitial fluid within a time period before the first moment and a glucose concentration in the interstitial fluid within a time period after the first moment. In the present application, the glucose concentration in the interstitial fluid within the time period after the first moment is taken into consideration, and an additional time period is provided for the diffusion of glucose between the interstitial fluid and blood; therefore, when the blood glucose level drastically changes, the glucose concentration in the interstitial fluid more closely approximates the blood glucose level, and thus the accuracy of blood glucose monitoring can be improved.

The invention relates to the technical field of medical apparatus and instruments, and discloses a ring-type noninvasive blood glucose detector capable of continuously monitoring blood glucose, comprising a shell sleeving a finger of a wearer; the signal acquisition part is arranged in a shell cavity of the shell, a gap is formed between the detection end of the signal acquisition part extending out of the inner side wall of the shell and the detection part, and the signal acquisition part is used for acquiring biological sign parameters and environmental characteristic parameters of the wearer; the limiting and fixing part is arranged on the shell, the limiting and fixing part and the shell form an annular structure, and the perimeter size of the inner side of the annular structure is adjusted through the limiting and fixing part; the transmission part is arranged in the shell, the biological sign parameters and the environment characteristic parameters of the wearer are calculated through the calculation module, and the calculated result is transmitted to mobile equipment of the wearer through the transmission part. The non-invasive blood glucose detection device realizes non-invasive blood glucose detection, avoids injury to users, is convenient to adjust, adapts to different users, and improves the measurement precision.

The invention relates to the technical field of intelligent diabetes treatment instruments, in particular to a closed-loop non-invasive insulin detection and precise infusion system which is characterized by comprising a blood glucose monitoring regulator, a non-invasive injector and a closed-loop control mechanism. The closed-loop control mechanism comprises a real-time blood glucose detection module, a temperature detection module, a blood glucose data processing module, a dose decision module, an injection pressure adjusting module, an injection channel control module, an insulin injection module and a closed-loop feedback module; noninvasive and high-sensitivity real-time blood glucose monitoring is achieved, the accuracy and timeliness of insulin administration are improved through trend prediction and individualized dose decision, meanwhile, multi-nozzle array piezoelectric needleless injection is combined with temperature compensation pressure regulation and a closed loop feedback correction mechanism, local tissue burden is effectively reduced, and the insulin administration efficiency is improved. And through multiple safety protection and wireless data transmission, remote monitoring and intelligent management are realized, so that the convenience, accuracy and reliability of blood glucose management of diabetic patients are greatly improved.

The invention discloses a blood glucose detection method based on a nucleic acid aptamer. The blood glucose detection method comprises the following steps: S1, constructing a compound; s2, realizing fluorescence signal change; s3, quantitatively analyzing the glucose concentration. The invention relates to the technical field of biological detection, in particular to a blood glucose detection method based on an aptamer, which has the following advantages: 1, high stability and low cost; 2, high specificity; 3, multifunctionality and expansibility are realized; and 4, determining a wide detection range and a linear relation.

The invention discloses a glucose detection device for synchronously collecting and analyzing sweat interstitial fluid and a manufacturing method, and belongs to the technical field of sensors. In the device, a sweat discharge module and an interstitial fluid discharge module are embedded and fixed in a supporting layer; the sealing layer, the body fluid storage layer and the flow guide layer jointly define a sweat storage cavity and an interstitial fluid storage cavity which are distributed at intervals, and a sweat pH sensing module and an interstitial fluid pH sensing module are fixed to the sealing layer; the flow guide layer, the microfluidic layer and the detection layer jointly define a sweat microfluidic detection cavity and an interstitial fluid microfluidic detection cavity, a sweat temperature sensing module and an interstitial fluid temperature sensing module are fixed on the flow guide layer, and a sweat glucose sensing module and an interstitial fluid glucose sensing module are fixed on the detection layer; a sweat collection module and an interstitial fluid collection module are embedded in the detection layer and the skin adhesion layer. The non-invasive, high-precision and continuous blood glucose detection is realized, the processing is convenient, the processing efficiency is high, and the cost is low.

The utility model relates to the technical field of blood glucose detection auxiliary devices, and discloses a blood glucose detection disc for clinical nursing of the endocrinology department, which comprises a tray, a storage drawer is arranged at the front end in the tray, and limiting structures for conveniently limiting the storage drawer and a cleaning drawer are arranged at the front end and the rear end of two sides of the tray. According to the blood glucose detection disc for clinical nursing of the endocrinology department, by arranging a connecting plate, a supporting rod, a limiting rod, a fixing block, a spring and a limiting sliding groove, when a storage drawer and a cleaning drawer need to be limited and fixed, the supporting rod is rotated downwards, so that the connecting plate is not fixed; the springs enable the limiting rods to rebound to the two sides of one ends of the storage drawer and the cleaning drawer through the elasticity of the springs, so that the storage drawer and the cleaning drawer can be limited and fixed, the storage drawer and the cleaning drawer are prevented from sliding accidentally, and the problem that the drawers for containing materials and tools are inconvenient to limit and fix is solved. And the drawer is easy to open accidentally.

The invention discloses an enzyme electrode method efficient blood glucose measuring device for real-time monitoring of diabetes, and relates to the technical field of blood glucose detection. The enzyme electrode method efficient blood glucose measuring device for real-time monitoring of diabetes mellitus comprises a detection box main body, a detection cavity is formed in the detection box main body, a detection opening used for stretching of the arm of a patient is formed in one side of the detection box main body, and a placement module is arranged in the detection cavity and used for bearing the arm, stretching into the detection opening, of the patient; a pressing limiting structure is arranged at the upper end of the placement module, and the bottom of the detection box main body is hollow and is provided with a supporting unit capable of being quickly opened and closed. According to the blood glucose measuring device, the blood sampling mode of the vein blood vessel of the arm of a patient is adopted to replace fingertip blood sampling, blood sampling obtained through fingertip blood sampling is capillary whole blood and contains tissue fluid, the measuring result is lower than the actual value, and the effect of venous blood sampled through the vein blood vessel is more accurate; the system is more suitable for real-time monitoring of patients in daily life.