137 results about "Blood glucose testing" patented technology

The embodiment of the invention provides a detachable detection device and a needle assistor, the detection device is used for detecting blood glucose, the detection device comprises a detection assembly, a sensor assembly and a needling assembly, the detection assembly comprises a flat shell, the outer wall of the bottom of the flat shell is sunken inwards to form a containing cavity, the sensor assembly comprises a base and a probe, the base is provided with a second via hole, and the probe is arranged in the containing cavity. The base is detachably clamped in the containing cavity, part of the probe is located in the base, part of the probe extends out of the hole wall of the second through hole and extends towards the side away from the detection assembly, and when the base is located in the containing cavity, the probe is electrically connected with the detection circuit board. According to the embodiment of the invention, the detection assembly and the sensor assembly are mutually detachable and can be clamped, so that only the sensor assembly is sterilized instead of the detection assembly in the sterilization process, and the influence on the detection circuit board in the detection assembly in the electromagnetic wave or irradiation sterilization process can be avoided; the product yield of the detection device is improved.

The invention discloses a glucometer high-precision detection method based on a dynamic calibration algorithm and a glucometer, and relates to the field of blood glucose detection.The method comprises the steps that modal decomposition is conducted on a blood glucose current signal, the blood glucose current signal is decomposed into a plurality of frequency components, and an effective physiological component and an interference component are separated from the frequency components; performing time sequence feature extraction on the effective physiological component to obtain feature parameters at multiple moments, and performing correlation analysis on the feature parameters at the multiple moments, the environment temperature and the tissue impedance parameter to obtain a fusion feature vector; inputting the fusion feature vector into a parameter calibration model, and outputting a preliminary blood glucose value; a temperature correction coefficient is calculated according to the deviation between the environment temperature and the preset reference temperature, the initial blood glucose value is dynamically adjusted according to the temperature correction coefficient, and a final blood glucose detection value is obtained. By implementing the method, the detection accuracy of the glucometer can be improved.

The embodiment of the invention provides a manufacturing method of a test paper connector, the test paper connector and a glucometer, and relates to the field of blood glucose detection. The manufacturing method of the test paper connector comprises the following steps: adjusting the height h of the pin of the test paper seat plug-in device to be lower than the height H of the positioning column; mounting a test paper holder plug-in device and a bottom surface component on the PCB; performing reflow soldering on the test paper holder plug-in device and the bottom surface component; and mounting a top surface component on the top surface of the PCB. According to the manufacturing method disclosed by the embodiment of the invention, the sizes of the positioning columns and the pins of the test paper seat plug-in device are adjusted, the pins are prevented from scraping a steel mesh, the test paper seat plug-in device is mounted in the jacks when the components on the bottom surface of the PCB are mounted, and then reflow soldering is performed together, so that the test paper seat plug-in device does not need to be manually post-welded, the operation step of manual welding is omitted, and the production efficiency is improved. One mounting operation procedure is reduced, the production efficiency can be improved, and the production cost is reduced. The embodiment of the invention also provides a test paper connector and a glucometer.

Provided in the present application are a blood glucose monitoring method and a related apparatus. In the method, the blood glucose level at a first moment can be acquired on the basis of a glucose concentration in interstitial fluid at the first moment, a glucose concentration in the interstitial fluid within a time period before the first moment and a glucose concentration in the interstitial fluid within a time period after the first moment. In the present application, the glucose concentration in the interstitial fluid within the time period after the first moment is taken into consideration, and an additional time period is provided for the diffusion of glucose between the interstitial fluid and blood; therefore, when the blood glucose level drastically changes, the glucose concentration in the interstitial fluid more closely approximates the blood glucose level, and thus the accuracy of blood glucose monitoring can be improved.

The invention relates to the technical field of intelligent diabetes treatment instruments, in particular to a closed-loop non-invasive insulin detection and precise infusion system which is characterized by comprising a blood glucose monitoring regulator, a non-invasive injector and a closed-loop control mechanism. The closed-loop control mechanism comprises a real-time blood glucose detection module, a temperature detection module, a blood glucose data processing module, a dose decision module, an injection pressure adjusting module, an injection channel control module, an insulin injection module and a closed-loop feedback module; noninvasive and high-sensitivity real-time blood glucose monitoring is achieved, the accuracy and timeliness of insulin administration are improved through trend prediction and individualized dose decision, meanwhile, multi-nozzle array piezoelectric needleless injection is combined with temperature compensation pressure regulation and a closed loop feedback correction mechanism, local tissue burden is effectively reduced, and the insulin administration efficiency is improved. And through multiple safety protection and wireless data transmission, remote monitoring and intelligent management are realized, so that the convenience, accuracy and reliability of blood glucose management of diabetic patients are greatly improved.

The utility model relates to the technical field of blood glucose detection auxiliary devices, and discloses a blood glucose detection disc for clinical nursing of the endocrinology department, which comprises a tray, a storage drawer is arranged at the front end in the tray, and limiting structures for conveniently limiting the storage drawer and a cleaning drawer are arranged at the front end and the rear end of two sides of the tray. According to the blood glucose detection disc for clinical nursing of the endocrinology department, by arranging a connecting plate, a supporting rod, a limiting rod, a fixing block, a spring and a limiting sliding groove, when a storage drawer and a cleaning drawer need to be limited and fixed, the supporting rod is rotated downwards, so that the connecting plate is not fixed; the springs enable the limiting rods to rebound to the two sides of one ends of the storage drawer and the cleaning drawer through the elasticity of the springs, so that the storage drawer and the cleaning drawer can be limited and fixed, the storage drawer and the cleaning drawer are prevented from sliding accidentally, and the problem that the drawers for containing materials and tools are inconvenient to limit and fix is solved. And the drawer is easy to open accidentally.

1. Name of the product in this design: Blood glucose meter. 2. Purpose of this design: For blood glucose testing. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

1. The name of the design product: blood glucose meter. 2. The use of the design product: the product is used with blood glucose test strips to measure and display blood glucose information. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The invention provides a food measuring device based on gestational diabetes mellitus of a pregnant woman, and relates to the technical field of diabetes mellitus medical equipment. Comprising a nutrition control mechanism and a blood sugar monitoring mechanism, and the nutrition control mechanism and the blood sugar monitoring mechanism are detachably connected; the nutrition control mechanism comprises a base, a limiting groove is formed in the base, a placement disc is arranged on the limiting groove, and a pressure sensor is arranged between the placement disc and the limiting groove; a telescopic rod is arranged on the base, and a camera is arranged on the telescopic rod; the blood glucose monitoring mechanism comprises a wearing main body, a blood glucose detector, a controller and a display screen are arranged on the wearing main body, and the controller is electrically connected with the blood glucose detector and the display screen; compared with the prior art, the device is simple in structure, convenient to use and carry and capable of effectively monitoring and controlling diet nutrition of the pregnant woman.

The embodiment of the invention provides printing ink for blood glucose test paper as well as a preparation method and application thereof, and belongs to the technical field of printing ink. The printing ink comprises the following components in parts by weight: 40-70 parts of thermoplastic acrylic resin; 30 to 50 parts of hydroxy acrylic resin; 20-30 parts of an organic solvent; 3-5 parts of a dispersant; 50 to 70 parts of titanium dioxide; 10 to 20 parts of filler; 0.5 to 2 parts of a defoaming agent; 0.5 to 2 parts of a drier; 5-10 parts of a cross-linking agent; the glass transition temperature Tg of the thermoplastic acrylic resin is 45-85 DEG C, the hydroxyl value of the hydroxy acrylic resin is 35-85 mg KOH / g, and the thermoplastic acrylic resin and the hydroxy acrylic resin form a compact three-dimensional network molecular chain structure under the action of the cross-linking agent. The printing ink provided by the invention has good biocompatibility and uniform film thickness, stably protects the isolation layer, and improves the performance of the test paper.

The utility model provides a blood glucose detector, which solves the problem that the existing blood glucose detector with a single cavity structure cannot meet the modern daily small and portable requirements and the like, and adopts the main scheme that the blood glucose detector comprises a first shell and a second shell, the top surface of the first shell is concavely provided with a first space, and an integrated special-shaped plate is fixed on one side of the top surface of the first shell; the special-shaped plate comprises at least one flange, the flange is smoothly connected with the outer edge of the top face of the first shell, the outer edge of the bottom face of the second shell and the flange and the outer edge of the flange connected with the top face of the first shell are magnetically attracted and fixed into a whole, the interior of the second shell is hollowed out, and the bottom face of the second shell is sealed through an assembly plate to form a second space. The first space is used for containing a needle head and test paper, a PCB and a display screen electrically connected with the PCB are arranged in the second space, and an insertion opening is formed in one side of the assembly plate so that the test paper can be inserted into the insertion opening to react with the PCB.

The application discloses a blood glucose detection test paper production equipment and relates to the field of test paper production, which comprises a processing table, a support is fixedly connected to the upper end face of the processing table close to the front side, a movable plate is slidably inserted into the support, three cutting knives are fixedly connected to the lower end face of the movable plate at equal intervals, and three discharge ports are formed in the upper end face of the processing table corresponding to the cutting knives. The two servo motors can drive the movable plate to reciprocate up and down in the support, thereby driving the cutting knives to cut the test paper sent to the discharge port. In the process of ascending of the movable plate, the upper ends of the two rotating plates are pushed away from each other by the push plate, thereby driving the two shovel plates to open. When the movable plate descends, the lower ends of the two rotating plates are driven away from each other by the push plate, thereby driving the two shovel plates to be attached to the front and back sides of the cutting knives, so that the glue adhered to the cutting knives is scraped off by the shovel plates in the process of continuous descending of the cutting knives, the sharpness of the cutting knives is ensured, and the cutting knives can smoothly cut the test paper.

1. Name of the product in this design: Biosensor Electrode Device. 2. Purpose of this design: For continuous blood glucose monitoring via partial implantation in subcutaneous tissue. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The application discloses an integrated automatic blood-squeezing peripheral blood glucose detection device, which comprises a host computer (1) and a detachably connected disposable sterile integrated core (2). The disposable sterile integrated core (2) comprises a microneedle assembly (4), an elastic squeezing structure (3) arranged around the microneedle assembly (4), a blood glucose detection test paper (6), a capillary blood guiding channel (5) and an electrode contact (7). When the microneedle assembly (4) completes skin puncture, the elastic squeezing structure (3) applies synchronous micro mechanical squeezing force to the tissue around the blood sampling site, so that blood seeps out and is automatically transported to the blood glucose detection test paper (6) through the capillary blood guiding channel (5). The blood glucose detection test paper (6) is internally integrated in the disposable sterile integrated core (2), and the electrode contact (7) is used for electrical connection with the host computer (1). The application realizes the integration of blood sampling, automatic blood squeezing, blood guiding and detection by using a pure mechanical structure, and does not need manual blood squeezing and manual sample adding. The application has the advantages of simple structure, low cost, simple operation, safety and sanitation, and is suitable for rapid blood glucose detection in family and hospital scenes.

The present application belongs to the technical field of medical health monitoring, and relates to a non-invasive blood glucose detection method based on reinforcement learning and multi-modal dynamic weight fusion. The method comprises: based on a reinforcement learning network, performing adaptive dynamic weight distribution on the weights of ECG signals and PPG signals, optimizing signal processing parameters, and confirming whether a threshold value is triggered for adjustment; performing weighted feature fusion on the ECG signals and PPG signals to obtain a fusion feature vector; inputting the fusion feature vector into a prediction and early warning double-branch output structure, wherein the prediction and early warning double-branch output structure comprises a regression branch and a classification branch, the regression branch is used for continuous prediction of blood glucose values, and finally outputs a single blood glucose concentration value; the classification branch is used for early warning level determination, and finally outputs a graded alarm for the continuous prediction result, so as to complete non-invasive blood glucose detection. The beneficial effects are that the fluctuation influence of user motion and temperature on non-invasive blood glucose data acquisition is reduced, and the individual difference adaptability and long-term stability of non-invasive blood glucose detection are improved.

The embodiment of the application provides a printing ink for blood glucose test paper, a preparation method and application thereof, and belongs to the technical field of printing ink.The printing ink comprises, by weight parts, 40-70 parts of thermoplastic acrylic resin, 30-50 parts of hydroxyl acrylic resin, 20-30 parts of organic solvent, 3-5 parts of dispersing agent, 50-70 parts of titanium white, 10-20 parts of filler, 0.5-2 parts of defoaming agent, 0.5-2 parts of drying agent, 5-10 parts of crosslinking agent, the glass transition temperature Tg of the thermoplastic acrylic resin is 45-85 DEG C, the hydroxyl value of the hydroxyl acrylic resin is 35-85 mg KOH / g, and the two form a dense three-dimensional network molecular chain structure under the action of the crosslinking agent.The printing ink has good biological compatibility and uniform film thickness, stably protects an isolation layer, and improves the performance of the test paper.

The application discloses a medical blood glucose test paper strip cutting and packaging production line and a process thereof, which comprises a material bucket vibration feeding module, a material bucket conveying line used for equidistantly conveying material buckets, a material bucket carrying mechanism, a test paper strip cutting and barrel filling mechanism, a CCD camera module, a weighing and distributing mechanism, a pressing and detecting mechanism, a barrel cap vibration feeding module and a barrel cap carrying mechanism.

The present application relates to the technical field of pattern recognition, in particular to a blood glucose detection region selection method based on blood perfusion imaging, comprising collecting continuous laser speckle original images of a to-be-detected skin region and a peripheral pulse wave signal of a subject, and constructing a bottom layer data matrix. The image sequence is converted into a perfusion contrast evolution sequence by calculating the ratio of the standard discrete degree and the average brightness of the pixel intensity in the three-dimensional data block. Frequency locking operation is performed using the main frequency of the pulse wave to separate out the perfusion fluctuation component synchronized with the heart beat rhythm, and the phase lag distribution map of each pixel point is determined through cross-correlation time delay analysis. The tissue damping coefficient of each pixel point is obtained by combining the tissue viscoelasticity kinetic damping model inversion, and the pixel set in the target response interval is screened and clustered according to the mapping relationship between the blood glucose concentration and the damping coefficient to determine the blood glucose detection target region. The present application realizes the locking of the detection region through tissue damping characteristic inversion and clustering screening.

The invention relates to the technical field of blood glucose detection, and particularly discloses a blood glucose monitoring method based on the content of glucose in saliva, which comprises the following steps: contacting a pretreated sample with a monitoring system, and connecting with an electrochemical workstation through the monitoring system, setting the working potential of the monitoring system through an electrochemical workstation, collecting the electric signal change of the monitoring system, and calculating the glucose content in the saliva according to the electric signal change so as to deduce the blood glucose level; and the monitoring system comprises a Ni5P4-FeP / Ti electrocatalyst. By adopting the technical scheme, the saliva pH environment can be met, the detection limit and precision meet the accurate glucose detection requirement, and the detection operation is simple.

The invention discloses a noninvasive blood glucose detection device based on multi-signal feature fusion, which comprises a host and an acquisition probe, and multiple signals comprise a photoacoustic signal and a photoelectric plethysmography (PPG) signal. By performing quality evaluation on the collected PPG signal, the optimal action position of the incident laser on the human body is positioned, so that the laser energy is concentrated in a blood vessel area, and the stability and repeatability of photoacoustic detection are improved. Meanwhile, feature extraction and fusion are performed on the photoacoustic signals and the PPG signals, and a blood glucose prediction regression model is established by utilizing a machine learning algorithm, so that the precision and reliability of noninvasive blood glucose detection are improved.

The invention belongs to the field of blood glucose detection, and relates to a high-sensitivity blood glucose noninvasive detection method and system based on polarized terahertz photoacoustic, which combines the advantages of terahertz wave band detection and photoacoustic detection, fully utilizes the chiral characteristics of glucose molecules, and adopts polarized terahertz photoacoustic to detect the blood glucose concentration. Polarization optical rotation change information is extracted through the time domain photoacoustic signal; by selecting the characteristic absorption wave band of glucose and utilizing the difference between glucose and other blood components in chiral characteristics, the influence of water and other high-concentration ions on terahertz signals is remarkably reduced, so that the selectivity and the anti-interference capability of blood glucose detection are effectively improved; terahertz non-ionizing radiation is adopted as an excitation source, no ionizing injury risk is caused to a human body, and the device is suitable for long-term repeated detection and is expected to be popularized and applied in wearable or bedside monitoring equipment.

The embodiment of the present application relates to a blood glucose prediction method and device combining a big data model and a personalized model, the method comprising: training a big data blood glucose prediction model; receiving a first collection data set of a specified object; updating a personalized database according to the first collection data set when the first data type is a label type; if the updating is successful, counting the total number of personalized data records to generate a first total number; if the first total number is greater than or equal to a first threshold value, screening personalized data calibration records; if the first total number is equal to a second threshold value, training a personalized blood glucose prediction model; when the first data type is a prediction type, counting the total number of personalized data records to generate a second total number; if the second total number is less than the second threshold value, predicting based on the big data blood glucose prediction model; and if the second total number is equal to the second threshold value, combining the big data and the personalized blood glucose prediction model to perform personalized blood glucose prediction. The present application can avoid the inconvenience caused by invasive blood glucose detection.

The invention discloses a noninvasive blood glucose detection device and method. The noninvasive blood glucose detection device comprises a radar transmitter, a radar receiver, a data acquisition module, a blind source separation module, a feature extraction module and a blood glucose evaluation module, a broadband radio frequency modulation signal emitted by the radar transmitter irradiates a certain human tissue, a reflected radio frequency signal is received by the radar receiver and then is converted into an analog baseband signal, and the analog baseband signal is sampled by the data acquisition module and then is converted into a digital signal. After the electromagnetic waves are transmitted to the blind source separation module for noise filtering, interference removal and data enhancement processing, feature information of the electromagnetic waves in the subcutaneous tissue blood transmission process is extracted, and then blood glucose concentration information is obtained through machine learning according to the feature information. When the device is used for measuring blood glucose, test paper or a reagent is not needed, and low detection cost, zero pollution, comfort and no feeling are realized.

1. The name of the design product: blood glucose meter. 2. The use of the design product: for blood glucose meter. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: design 1 perspective view 1. 5. Design 1 is designated as the basic design.

The invention discloses a wearable sensor-minimally invasive diabetes monitoring patch and a preparation method thereof, and belongs to the technical field of biomedicine, the patch comprises a microneedle array module and a sensing unit; the microneedle array module is composed of a plurality of microneedles arranged in an array; the sensing unit is loaded in the microneedle, and the sensing unit comprises a multi-shell metal organic framework cascade enzyme system and a chromogenic substrate; the multi-shell metal organic framework cascade enzyme system is of a double-layer structure composed of an inner core and an outer shell, the inner core is a metal organic framework packaged with glucose oxidase and modified with carboxyl functional groups, and the outer shell is a metal organic framework packaged with horse radish peroxidase. And 2, 2-nitrogen-bis (3-ethylbenzothiazoline-6-sulfonic acid) is taken as a chromogenic substrate. According to the patch, the catalytic efficiency and the detection accuracy are improved, the stability is improved, the storage and transportation cost is reduced, the low detection limit can be achieved, the requirement for instant blood glucose detection is met, the size is small, and the cost is low.

This application relates to the field of blood glucose detection technology, and in particular to a non-invasive / minimally invasive blood glucose prediction system, method, and storage medium. The system includes a data acquisition module for acquiring blood glucose and physiological parameters non-invasively and minimally invasively, and inputting them into a blood glucose detection model; and a blood glucose prediction module for outputting predicted blood glucose values ​​through the blood glucose detection model. This application overcomes the limitation of conventional blood glucose detection models that rely solely on single real-time data by deeply integrating blood glucose and physiological parameters. Physiological parameters reflect the impact of real-time physiological state on blood glucose; blood glucose parameters reflect the current trend of blood glucose changes; and the blood glucose detection model establishes a correlation mechanism for blood glucose changes, facilitating patient self-management and remote monitoring by medical staff, providing reliable assurance for the long-term management of diabetic patients.

The invention belongs to the technical field of semiconductor technologies, and discloses a blood glucose detection device based on a non-toxic colloidal quantum dot photodiode, which comprises a near-infrared light source module, a photoelectric conversion module, a signal processing module and a blood glucose calculation module, the photoelectric conversion module is a non-toxic colloidal quantum dot photodiode; the non-toxic colloid quantum dot photodiode comprises a bottom reflection electrode, a DBR layer, an N-type layer, an absorption layer, a P-type layer and a top transparent electrode which are sequentially stacked. The N-type layer is a TiO2 or ZnO nano particle layer; the absorption layer is an intrinsic AgBiS2 and ZnTe mixed colloid quantum dot layer; the P-type layer is a CuInS2 colloidal quantum dot layer; the top transparent electrode is made of ITO or AZO. The long-term safety of the device can be remarkably improved, and the device is more suitable for non-invasive wearable blood glucose monitoring application which is in contact with or is attached to the skin of the human body.

This disclosure relates to a sensor detachment detection method for blood glucose testing, comprising: acquiring the sensor's test current; when the test current is greater than a standard value, outputting a first-level signal at the output terminal of the current processing circuit; triggering the detection circuit to perform multiple rounds of repeated detection; ending the loop detection when the cumulative number of times the counter is greater than or equal to a predetermined threshold; setting to enter a detachment detection mode, and determining sensor detachment when the current after amplification is still less than the current threshold. The above-mentioned technical solution of this application can avoid large currents generated by system circuit malfunctions, and uses multiple detections to filter out the influence of interference signals, avoiding false detections. This achieves reliable sensor detachment detection.

The utility model discloses a blood glucose test paper box, relates to the field of medical articles, and provides a blood glucose test paper box which is favorable for preventing test paper from being polluted when the test paper is taken. The blood glucose test paper box comprises a test paper box main body, an output port cover and a cover connecting structure, a test paper outlet matched with blood glucose test paper is formed in a top plate of the test paper box main body, and the output port cover covers the test paper box main body; the box cover connecting structure comprises a guide rail, a sliding block and a connecting strip, the guide rail is vertically arranged beside the test paper box body and connected with the test paper box body, the sliding block is matched with the guide rail, the upper end and the lower end of the connecting strip are connected with the output port cover and the sliding block respectively, and the output port cover can move upwards to a first position and a second position; when the output port cover is located at the first position, the distance between the upper edge of the test paper outlet and the output port cover is a, when the output port cover is located at the second position, the distance between the upper edge of the test paper outlet and the output port cover is b, the length of the blood glucose test paper is c, 5 mm < = c-a < = 10 mm, and b > c.