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Methods and systems for monitoring hadron beams during hadron therapy treatment of subject

A subject, hadron beam technology, used in X-ray/γ-ray/particle irradiation therapy, therapy, radiotherapy, etc., to solve problems such as deviation

Pending Publication Date: 2022-07-15
CENT NAT DE LA RECHERCHE SCI +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Indeed, deviations of the tumor volume relative to the external anatomical landmarks used to align the patient with respect to the beam can have serious consequences as the dose will not be delivered according to the treatment plan and thus healthy tissue will be irradiated

Method used

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  • Methods and systems for monitoring hadron beams during hadron therapy treatment of subject
  • Methods and systems for monitoring hadron beams during hadron therapy treatment of subject
  • Methods and systems for monitoring hadron beams during hadron therapy treatment of subject

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Embodiment Construction

[0050] Features and advantages of the present invention will emerge from the following description of several embodiments of the system and method according to the present invention, given by way of non-limiting example only and with reference to the accompanying drawings, wherein:

[0051] figure 1 is a schematic perspective view of a treatment table and Compton telescope in an open configuration according to a first embodiment of the present invention;

[0052] figure 2 is a flow chart representing the steps of the method according to the first embodiment of the present invention;

[0053] image 3 is a schematic perspective view of a treatment table and Compton telescope in an open configuration according to a second embodiment of the present invention;

[0054] Figure 4 is a schematic perspective view of a treatment table and a Compton telescope in a closed configuration according to a third embodiment of the present invention.

[0055] The present invention relates...

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Abstract

The present invention relates to a method for monitoring a hadron bundle during hadron therapy treatment of a subject comprising tumor cells labeled with a radiopharmaceutical product wherein the hadron bundle comprises a plurality of discrete hadron bursts, the method comprising the steps of: when the bursts strike the subject, monitoring the hadron bursts in the subject; detecting (111), by a Compton telescope, instantaneous gamma rays resulting from the interaction of the outbreak hadron with the tissue of the subject, and reconstructing (112) an image of the interaction volume; extracting (121), by a Compton telescope, the locations of the tumor cells labeled with the radiopharmaceutical product when no burst impacts the subject, reconstructing (122) an image of the total tumor volume; the image of the interaction volume and the image of the total tumor volume are compared (131) in order to locate the measured interaction volume relative to the measured total tumor volume.

Description

technical field [0001] The present invention relates to a system and method for monitoring a hadron beam during hadron therapy treatment of a subject with cancer. In particular, the present invention relates to a system and method for monitoring the area of ​​interaction between a hadron beam and tissue of a subject, and thus indirectly monitoring the delivered dose relative to the tumor mass to be treated, the tumor mass Radiopharmaceutical products have been labeled with radioisotopes that emit positrons and de-excite gamma rays in a quasi-coincidence. Background technique [0002] Hadron therapy is a highly effective cancer therapy that uses a beam of proton particles or carbon ions. This innovative technique has been shown to be effective for tumors that are difficult to treat with conventional radiation therapy because these tumors are radiation-resistant or located deep or close to vital organs. The use of hadron beams enables very precise dose deposition both longit...

Claims

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Application Information

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IPC IPC(8): A61N5/10
CPCA61N5/1049A61N5/1064A61N5/1067A61N5/107A61N2005/1061
Inventor 多米尼克·特尔斯珍-塞巴斯蒂安·斯图茨曼
Owner CENT NAT DE LA RECHERCHE SCI
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