Unlock instant, AI-driven research and patent intelligence for your innovation.

Compound bergenin pills and its preparation method

A technology of petracenin and rock cabbage, which is applied in the field of drugs for the treatment of chronic bronchitis and cold and cough, and can solve the problems of slow dissolution, low bioavailability, and affecting the best efficacy

Inactive Publication Date: 2006-07-12
YUNNAN BAIYAO GROUP
View PDF0 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main reason is that petracenin is a water-insoluble drug, and the tablet made by the general pulverization process dissolves slowly in the human body and has low bioavailability, which affects the best efficacy.
Therefore, how to improve the bioavailability of petracenin preparations after oral administration is an important problem in this field, which has not been solved so far.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Compound bergenin pills and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: Get 30 parts of petracenin, 0.48 parts of chlorpheniramine, 269.52 parts of PEG6000, and make the finished product of dripping pills containing 3 mg of petracenin according to the above-mentioned melting method.

Embodiment 2

[0035] Embodiment 2: Get 45 parts of petracenin, 0.72 parts of chlorpheniramine, 254.28 parts of PEG4000, and process according to the above-mentioned melting method to obtain the finished product of dripping pills containing 4.5 mg of petracenin.

Embodiment 3

[0036] Embodiment 3: Get 60 parts of petracenin, 0.96 parts of chlorpheniramine, 239.04 parts of PEG6000, and make the finished product of dripping pills containing 6 mg of petracenin according to the above-mentioned melting method.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a novel medicinal dosage for treating chronic bronchitis and common cold, and its preparing process, which comprises medicinal active constituents and medicinal auxiliary materials, wherein the active components of the medicament include Bergenin 8-42 wt% and chlorpheniramine 0.001-0.01 wt%, and balancing medicinal auxiliary materials.

Description

technical field [0001] The invention relates to a medicine for treating chronic bronchitis and cold and cough, especially the medicine in a new dosage form and a preparation method thereof. Background technique [0002] Petgenin is an extract of botanical medicine, which has antitussive and expectorant effects and can be used to treat chronic bronchitis. The curative effect is certain, but the onset time is slow. The main reason is that petracenin is a poorly water-soluble drug, and tablets made by general pulverization process dissolve slowly in the human body and have low bioavailability, thus affecting the best efficacy. Therefore, how to improve the bioavailability of petracenin preparations after oral administration is an important problem in this field, which has not been solved so far. Contents of the invention [0003] The purpose of the present invention is to overcome the deficiencies in the prior art, and provide a compound lithenol dropping pill with high dis...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/4402A61K31/366A61K9/20A61P11/00A61P11/14
Inventor 陈庆党何国民宾燕
Owner YUNNAN BAIYAO GROUP