Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for determining an integral sun protection factor encompassing UVA and UVB radiation

A technology of sun protection index and sunscreen agent, which is applied in the direction of magnetic resonance measurement and measurement by electron paramagnetic resonance, can solve the problems of incapable of moderate change, non-quantifiable protection, and no longer suitable for correctly expressing the protection effect of sunscreen agents, etc. The effect of waiting time

Inactive Publication Date: 2012-03-21
COTY BV +1
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, sunscreens contain varying amounts of UVA and / or UVB filters and therefore do not provide moderately variable and non-quantifiable protection against free radicals in most cases
Today's SPF / LSF is only related to the effect of UVB, it seems that it is no longer suitable to correctly represent the protective effect of sunscreen

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for determining an integral sun protection factor encompassing UVA and UVB radiation
  • Method for determining an integral sun protection factor encompassing UVA and UVB radiation
  • Method for determining an integral sun protection factor encompassing UVA and UVB radiation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1 and 2

[0103] Two different sunscreen samples were tested, both obtained higher protection in UVB and different levels of UVA protection: Sunscreen A is a physical sunscreen TiO 2 , SPF is 26, UVA PF (PPD) = 5; Sunscreen B is a UV filter organic sunscreen, SPF is 39, UVA PF (PPD) = 12.

[0104] Both products are available at 2mg / cm 2 For use on the skin surface and tested based on three exposure times. Biopsied skin without sunscreen was also tested in parallel, with one group exposed directly to a solar simulator and a second group exposed through a neutral density filter with an attenuation of 30. Each free radical formation data reported in Table 3 is the average of four biopsies.

[0105] Table 3: Free radical formation at different irradiation times

[0106] (RG=X·10 12 rad / mg)

[0107] Exposure time (seconds) X Blank No attenuation X neutral filter attenuation 30 XSunscreen A XSunscreen B 60s 1.82 0.34 0.62 0.48 120s 2.36 0....

Embodiment 3-8

[0130] To determine the selectivity of integrated SPF for different UV filter widths, specific sunscreen formulations were obtained with different UVB and / or broadband UVA / B filters.

Embodiment 3

[0131] Example 3 = sunscreen C = O-W base, no UV filter

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for determining an integral sun protection factor (summa SPF or iSPF) which encompasses both UVA and UVB radiation and can be used for classifying cosmetic and dermatological sunscreens. The method comprises the steps of applying a defined amount of the sunscreen onto a defined area of a skin substrate impregnated with a spin trap, exposing the skin substrate to a defined amount of UVA- and UVB rays by a sun simulator, subjecting the skin substrate exposed to radiation to an electron spin resonance (ESR) measurement, recording the number of free radicals trapped as a real number x 1012 free radicals / mg of skin sample, and determining the integral sun protection factor o SPF according to the equations (1) and (2) and (8).

Description

technical field [0001] The present invention relates to a method for determining an integral sun protection factor (∫SPF or iSPF) including UVA and UVB radiation, which can be used to classify cosmetic and dermatological sunscreens. Background technique [0002] It is well known that UV radiation greatly increases the production of free radicals in the skin. Generates reactive oxygen species such as hydroxyl radicals * Oh - , superoxide anion radical O 2 - and singlet molecular oxygen 1 o 2 , which in turn will allow the formation of lipid radicals L * . Cosmetic and dermatological sunscreen preparations therefore contain UV filters and additionally contain small amounts of antioxidants. [0003] In addition, it is known from the publications of the 22nd World Federation of Cosmetic Chemists Symposium (Edinburgh 2002, Oral Papers, Vol.2, Zastrow et al.) and other publications that imaging by electron spin resonance (ESR) has been Determine the different depths at wh...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01R33/60
CPCG01R33/60
Inventor L·费雷罗L·扎斯特罗K·戈尔斯-伯纳N·格罗斯T·赫尔林
Owner COTY BV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com