The composition for predicting Alzheimer's
disease prognosis comprising a detection
reagent that specifically binds to any one or more genes selected from the group consisting of Nos1 (
Nitric oxide synthase 1), Aph1B (Anterior
pharynx defective 1 homolog B), Ryr3 (
Ryanodine receptor 3), Atf6 (Activating
transcriptional factor 6), Ip3r (
Inositol trisphosphate
receptor), Nep (Neprilysin), Cdk5 (
cyclin dependent
kinase 5) and Abad (
Amyloid beta-binding
alcohol dehydrogenase), a kit, and a method for providing information on Alzheimer's
disease prognosis of the present invention can rapidly and accurately predict the prognosis of Alzheimer's
disease, and can determine the prognosis for a
drug by comparing the expression level before and after
drug administration, so that an appropriate treatment direction can be determined according to the predicted prognosis. Therefore, they have an effect that can greatly contribute to the reduction of mortality due to Alzheimer's disease.