90results about How to "Uniform dosing" patented technology

A charged particle beam irradiation system includes measurement means 15 for measuring an accumulated beam charge amount Qm0, the ion beams orbiting in a synchrotron 13, immediately before an extraction control period in an operating cycle of the synchrotron 13; and beam extraction control means 20, 24, 28, 29 for controlling extraction of the ion beams so that extraction of a total of the ion beams is to be completed in time with expiration of an extraction control time Tex which is set in advance based on the measurement Qm0 of the accumulated beam charge amount. When an irradiation apparatus includes an RMW 32, an amplitude of an extraction radiofrequency voltage is controlled according to a ratio Qm0/Qs0 of the measurement to a reference value of the accumulated beam charge amount and a ratio Tb/Ta of an actual beam extraction time to the extraction control time Tex.

An expandable stent is fabricated from a plurality of circumferential rings, each pair of adjacent circumferential rings being interconnected by a multiplicity of links, each link contacting a portion of a strut in one ring along one longitudinal axis and a portion a strut in a directly adjacent ring along a different longitudinal axis. Each link is circumferentially S-shaped and adjacent links are mirror images of each other. The resulting stent is both flexible and strong when expanded thereby providing good scaffolding. In one embodiment, the strut material is fabricated of shape memory alloy such that when the strut is compressed so as to be insertable into a vessel, the strut will automatically expand to its previous dimension upon rising to the temperature of the vessel in which it is placed, thereby to expand and hold open the vessel without need for a balloon catheter.

A therapy apparatus for producing thermal neutrons at a tumor site in a patient has a plurality of fast neutron sources surrounding a moderator, a fast neutron reflecting media around the fast neutron sources, a gamma-ray and neutron shielding media surrounding the fast neutron reflecting media, and a patient chamber positioned inside the moderator. The fast neutron sources are positioned around the moderator to maximize and direct the neutron flux to said tumor site.

Methods and apparatuses for coating surface of medical devices using coating heads are disclosed. In one embodiment, the invention includes a coating method using a coating head, wherein the coating head comprises at least one outlet orifice from which flows a coating material, to deposit at least one layer of coating material dispelled through the outlet orifice onto the surface of the medical device. In another embodiment, a slide coating head is used to deposit multiple layers of superposed coating materials. These methods are used to apply one or more coating materials, simultaneously or in sequence. In certain embodiments of the invention, the coating materials include therapeutic agents, polymers, sugars, waxes, or fats.

The invention discloses a gynecology administration device. The gynecology administration device comprises a drug pushing tube, an outer sleeve and a drug distributing tube, wherein the drug pushing tube is provided with a drug inlet and outlet hole in the front end face, and a first O-type ring is fixed to the outer side wall of the front end of the drug pushing tube; the outer sleeve is arranged outside the drug pushing tube in a sleeving mode, and a second O-type ring is fixed to the inner side of the front end of the outer sleeve; the drug distributing tube is arranged outside the drug pushing tube in a sleeving mode, the rear end of the drug distributing tube is connected with the outer sleeve in a sealed mode, administration holes are formed in the bottom and the side wall of the drug distributing tube, a communicating groove is formed in the inner tube wall of the drug distributing tube, and when the front end of the drug pushing tube abuts against a limiting protrusion, interlayer spaces before and after the first O-type ring are communicated. The administration device discharges a drug through the multiple holes, administrates the drug evenly, is large in acting surface, prevents the drug from accumulating locally, and ensures that the drug fast takes effect on the focus portion in time, and therefore the use efficiency and the treatment effect of the drug are improved; the drug distributing tube is disposable, so that the gynecology administration device is safe and sanitary, the drug pushing tube and the outer sleeve are convenient to clean and can be recycled, and therefore the cost of treating gynecological disease is reduced; excessive drug residue can be avoided, drug waste is reduced, and the gynecology administration device can be operated coherently, smoothly and easily.

Methods and apparatuses for coating surfaces of medical devices by electroplating are disclosed. In one embodiment, the invention includes a coating method in which a mixture of a therapeutic agent, and a plating material are electroplated onto the surface of the medical device. The electroplating method may be performed at a relatively low temperature to avoid destruction of the therapeutic agent. In another embodiment, a coating method is disclosed in which the coating is formed by suspending a therapeutic agent in an electrolytic solution and electroplating a plating material onto the medical device wherein the plating material carries the suspended therapeutic agent. Thus, the coating of plating material contains the suspended therapeutic agent. These methods and apparatuses are used to apply one or more coating materials, simultaneously or in sequence by varying the electroplating voltage. In certain embodiments of the invention, the coating materials include therapeutic agents and cationic drugs.

The invention belongs to the field of medical instruments and relates to cavitary mucosal drug delivery devices, in particular to an intelligent cavitary mucosal drug delivery device. The device comprises a display control operation platform, a heating sleeve, a peristaltic pump, a controllable liquid medicine valve and a micro wireless camera. The device is also provided with a wireless signal processor, the micro wireless camera transmits an observed image to the display control operation platform through the wireless signal processor, and the display control operation platform is connected with other equipment through a wire communication circuit to control the equipment. Through the combination of wire communication and wireless arrangement, the operability and data signal transmission effect of the device can be improved to a large extent, the device is convenient to operate, good in drug feeding effect, uniform in drug delivery, high in automation degree and capable of saving more labor, and the device is more intelligent compared with the prior art.

The invention discloses a double-balloon precise quantitative drug injection catheter. The catheter comprises a guide wire, a main catheter body and a balloon, the balloon is composed of an inner balloon body and an outer balloon body, the main catheter body is arranged in the middle of the outer balloon body and the inner balloon body, the guide wire is arranged in the main catheter body, the guide wire penetrates through a guide wire inlet formed in the main catheter body and penetrates out from a guide wire outlet, the main catheter body is internally provided with a pressure catheter bodyand a drug injection catheter body, the outlet end of the drug injection catheter body penetrates through the catheter and placed in a gap between the inner balloon body and the outer balloon body, the other end of the drug injection catheter body is connected with a drug injection pump, ad a control valve is arranged on the drug injection catheter body. The outlet end of the pressure catheter body penetrates through the main catheter body to be communicated with the inner balloon body, and the other end of the pressure catheter body is connected with a pressure pump. Accordingly, precise control over the dosage of applied drugs can be achieved, the drug injection amount and pressure size are controlled through a drug injection pipe and a pressure pipe respectively, drugs are injected intothe endovascular wall, dosing is uniform, the drugs are not wasted, the drugs can be fully utilized, drug injection can be conducted repeatedly, and the type of drug injection can be changed.

The invention relates to an invermectin in-vivo gel injection and a preparation method thereof, aiming at providing a long-acting injection for preventing and treating livestock parasite infections, and a preparation method thereof. Raw materials required by every 100 mL of the invermectin in-vivo gel injection comprise 5 g-10 g of injection grade invermectin, 10 g-20 g of poly(lactic-co-glycolicacid) (PLGA), 1 g -2 g of carbomer-941, 0.1 g -0.2 g of tween-80 and 85 mL-90 mL of an organic solvent. The injection is an in-vivo gel prepared from invermectin, and is used for preventing and treating gastrointestinal parasites of cattle, pigs and sheep, lungworm and externally parasitic diseases such as lice, and mites and fly larvae. The injection has an obvious effect; and the preparation method of the injection is simple and easily operational, and is suitable for large-scale production.

A laser interference lithography system with flat-top intensity profile comprises a laser source for emitting a coherent laser beam, a first beam expander for adjusting the coherent laser beam size, a refractive beam shaper for converting a Gaussian intensity profile inherent to the coherent laser beam into a flat-top one and outputting a first collimated laser beam, a second beam expander for receiving the first collimated laser beam and outputting a second collimated laser beam, a sample holder for holding a substrate, and at least one reflector for reflecting the second collimated laser beam to generate a third collimated laser beam. The second and third collimated laser beams are transmitted to the substrate at a predetermined angle to create an interference pattern exposed onto the substrate.

A method and a device are disclosed for transdermal delivery to an animal or human of biological cargo-laden nanoparticles. The particles may include multimodal optical molecular imaging probes. The particles may be delivered by providing them in a form that can be absorbed through the skin and applying them to the skin of an animal or human. The application may be accomplished using biological cargo-laden nanoparticles in a device attachable to the skin. The device may be attached directly to the skin by a device containing a vasodilating agent or agents, or micro needles, or multi-layer time release material. The biological cargo-laden nanoparticles may comprise drugs, vaccines, bio-pharmaceuticals, imaging contrast agents, multimodal imaging contrast agents, biomolecules, or anti-infectives. The device may include a first plurality of different types of biological cargo-laden nanoparticles located in a corresponding second plurality of separate time release layers.

The invention relates to an environment protective type casting system of aerosol, which comprises one or several propellants, by employing the environment-friendly type propellant separately, or using the environment-friendly type propellant system consisting of several propellants, the compatibility of the feed liquid can be improved substantially.

A spraying drug delivery device comprises a sleeve, wherein an internal cavity is formed in the sleeve and can accommodate a needle cylinder of a syringe; and at least one spray nozzle, wherein the spray nozzles are arranged at the front end of the sleeve and communicate with the internal cavity of the sleeve. An axial direction of each spray nozzle forms an angle with an axial direction of the sleeve. A finger-pressure pinch plate may also be formed at or adjacent to the rear end of the sleeve. Two spray nozzles can also be arranged at the front end of the sleeve. The spraying drug delivery device can achieve full spraying of medicated liquid, uniform drug delivery and leakage prevention. The invention further relates to a spraying drug delivery system comprising the device.

The present invention relates to the field of mechanical technology, in particular to a visualized anorectal drug delivery device, which includes a drug delivery tube, one end of the drug delivery tube is provided with a flexible end, a camera is embedded in the outer wall of the flexible end, a fixing ring is arranged on the outer surface of one end of the drug delivery tube away from the flexible end, a telescopic device is connected to one end of that drug delivery tube away from the flexible end, the surface of the drug delivery tube is provided with a plurality of sustained-release tabletplacing grooves, a sustained-release tablet is arranged inside the sustained-release tablet placing groove, a fixing paste is arranged on the top of the sustained-release tablet placing groove, the surface of the drug delivery tube is also provided with a lubricant placing groove, the lubricant placing groove is internally provided with a fixing column, The outer side of the fixed column is wrapped with vaseline. The invention has simple structure and convenient use. The drug administration tube can ensure uniform administration to the inside of the patient's anus and intestine, and can adjust the drug administration depth and improve the drug administration effect. The vaseline can further lubricate the outer wall of the drug administration tube and avoid the friction between the drug administration tube and the inside wall of the patient's anus and intestine from causing discomfort to the patient.

The invention discloses an outer mixing double fluid fan-shaped spray nozzle which comprises a nozzle body, a nozzle, a supporting pipe, a seal cover and a central pipe, wherein a through hole is formed in the central position of the seal cover; one end of the central pipe is inserted into the supporting pipe through the through hole and the inner part of the nozzle is hermetically connected to the seal cover; and an annular cavity where water circulates is formed between the outer side wall of the central pipe and the inner side walls of the supporting pipe and the nozzle. According to the nozzle structure, a biological pesticide and water are sprayed out through the central pipe and the annular cavity, separately, solid particles such as biological living bodies and auxiliary agents in apesticide are prevented from being in contact with and colliding with the nozzle under protection of water, the erosive wear of the nozzle is reduced, and the damage of microbial cells at the nozzleis also reduced, so that a pest control purpose is achieved.

The invention discloses a preparation method of tissue engineering skin, belongs to the technical field of tissue engineering and aims to solve the problem that defects exist in current making methodsof tissue engineering skin support materials and interaction mode of cells and the support materials. The preparation method includes following steps: (1), preparing a nano electrostatic spinning material; (2), culturing human body skin cells; (3), culturing the cells onto a nanofiber material. The preparation method is simple in building method and few in operation step, and good animal in-vivoexperiment effect can be acquired.