Polymer bactericide with anticoccidial effect

A technology of polymer and poultry coccidiosis, applied in the field of medicine, can solve the problems of chicken death, other diseases easily, and large breeding loss

Inactive Publication Date: 2009-12-16
QINGDAO VLAND BIOTECH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Coccidiosis is one of the main diseases of poultry. In addition to causing the death of chickens, this disease will also lead to poor uniformity of chicken flocks, lower feed remuneration, and other diseases easily, resulting in huge breeding losses

Method used

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  • Polymer bactericide with anticoccidial effect
  • Polymer bactericide with anticoccidial effect
  • Polymer bactericide with anticoccidial effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0110] Embodiment 1, synthetic experiment

[0111] The synthesis of the representative drug of the present invention (acrylic acid: acrolein: fumaric acid=63:30:7 in molar ratio): 73.7 g of freshly distilled acrolein, 198.8 g of freshly distilled acrylic acid and reaction Add 35.6g of butenedioic acid into a three-necked flask containing 630ml of anhydrous methanol, exhaust with nitrogen, then add 13.2g of benzoyl peroxide, heat and reflux for 70 hours under the protection of nitrogen, and the reaction solution turns into a brown viscous liquid , concentrated to dryness under reduced pressure, and maintained at 50-100° C. for 24 hours to obtain poly(acrylic acid, acrolein, fumaric acid) named polymer A.

Embodiment 2

[0112] Embodiment 2, polymer B

[0113] According to the preparation method of Example 1, the molar ratio of acrylic acid: acrolein: fumaric acid = 40:50:10 was synthesized to obtain poly(acrylic acid, acrolein, fumaric acid) and named polymer B.

[0114] Preferred is acrylic acid:acrolein:fumaric acid=0-98:1-50:0-50. A further preferred molar ratio of the three is acrylic acid:acrolein:fumaric acid=40-90:10-50:0-10. A further preferred molar ratio of the three is acrylic acid:acrolein:fumaric acid=50-70:20-40:5-9.

Embodiment 3

[0115] Embodiment 3, polymer C

[0116] According to the preparation method of Example 1, the molar ratio of acrylic acid:acrolein:fumaric acid=90:10:3 was synthesized to obtain poly(acrylic acid, acrolein, fumaric acid) and named polymer C.

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Abstract

The invention relates to a polymer for treating coccidiosis of poultry, which is a terpolymer having a molecular weight greater than 1,000 and formed by copolymerizing acrylic aldehyde, crylic acid, low-alkyl alkenyl acid or polyprotic acid.

Description

Technical field: [0001] The invention relates to the field of medicine, and relates to a polymer for treating poultry coccidiosis. The polymer is a terpolymer with a molecular weight greater than 1000 formed by copolymerization of acrolein, acrylic acid, or a lower alkenyl diacid or a polybasic acid. . Background technique: [0002] Coccidiosis is one of the main diseases of poultry. In addition to causing the death of chickens, this disease will also lead to poor uniformity of chicken flocks, reduced feed remuneration, and easily secondary to other diseases, resulting in huge breeding losses. Coccidiosis costs $350 million a year worldwide and is increasingly resistant to most commonly used drugs. [0003] Patent No.: CN200810147235.8, the patent titled "A Bactericidal Polymer and Its Preparation Method" relates to a new polymer with a bactericidal effect against bacterial and parasitic infections in animals and humans. It has been mentioned that the polymer The applicati...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/78A61K31/765A61K31/19A61P33/00A61P31/00
Inventor 殷生章王巧玲张志勇徐楷王英俊白金宇
Owner QINGDAO VLAND BIOTECH INC
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