6 results about "Butenedioic acid" patented technology

This invention provides a breathable plaster matrix for application and its preparation method, belonging to the field of polymeric dressings and plasters. The plaster matrix raw materials include terpene-modified rosin beeswax, hydrogenated rosin glyceryl ester, camellia oil, castor oil, stearic acid hydrophobically modified microcrystalline cellulose, zinc oxide, glycerin, coated citric acid, sodium bicarbonate, polyethylene glycol, camphor, and menthol. The terpene-modified rosin beeswax is prepared by reacting rosin and α-pinene in the presence of di-tert-butylperoxyisopropylbenzene, followed by the addition of white beeswax and maleic anhydride, and then the addition of trimethylolpropane. The stearic acid hydrophobically modified microcrystalline cellulose is microcrystalline cellulose coated with stearic acid. The coated citric acid is citric acid coated with hydrogenated castor oil. This invention's plaster matrix significantly improves skin breathability, application comfort, and biocompatibility while ensuring sufficient adhesion, formability, and drug loading capacity.

A process and apparatus for the production of maleic anhydride by reacting a mixed gas containing molecular oxygen and a hydrocarbon, usually n-butane, over a suitable catalyst, wherein the maleic anhydride is produced in a tubular catalytic reactor, wherein after recovery of the maleic anhydride product by absorption with an organic solvent and after appropriate treatment steps, the gaseous effluent from the reactor is recycled back to the inlet of the catalytic reactor by compression.

The present application relates to the field of new material fine chemicals, and particularly relates to a low-cost preparation of a series of carbon four (C4) diacid (ester) by using coal chemical industry abundant oxalate and / or glycollic acid (ester) bulk raw materials, including butene diacid (ester), succinic acid (ester), tartaric acid (ester), and / or malic acid (ester) and the like, and the process features are that all of the coal chemical industry abundant carbon monoxide (synthesis gas), methanol, or formaldehyde and the like bulk C1 raw materials are used, and a series of C4 skeleton products are simply and efficiently prepared. The technology practices outstanding cost reduction and efficiency improvement results, and is beneficial to large-scale preparation of high-value chemicals relying on rich coal resources in China.

The present invention relates to novel linkers containing a 2,3-disubstituted succinic group, or 2-monosubstituted, or 2,3-disubstituted fumaric or maleic (trans (E)- or cis (Z)-butenedioic), or acetylenedicarboxyl group for conjugation of a cytotoxic agent, and / or one or more different functional molecules per linker to a cell-binding molecule, through bridge linking pairs of thiols on the cell-binding molecule specifically. The invention also relates to methods of making such linkers, and of using such linkers in making homogeneous conjugates, as well as of application of the conjugates in treatment of cancers, infections and autoimmune disorders.

The utility model discloses a maleic anhydride tail gas purification system and the system of preparation maleic anhydride relates to the technical field of chemical production. Including first washing tower, compression unit, heat exchange device and second washing tower that are connected in turn, and the outlet of second washing tower and the inlet of gas -gas heat exchange medium passage of heat exchange device form loop, and the outlet of gas -gas heat exchange medium passage is configured as with maleic anhydride reaction system through pipeline intercommunication, to make maleic anhydride tail gas flow through first washing tower, compression unit, heat exchange device and second washing tower in proper order, and after two times washing, after heat exchange in heat exchange device, exhaust. The system not only can recycle and utilize the n-butane that is not completely reacted in maleic anhydride tail gas, reduces the loss of n-butane, improves economic efficiency, and can avoid organic acid and other byproducts and n-butane return to reactor system together, avoids equipment corrosion, improves system safety. Simultaneously through to the effective utilization of heat, has the effect of energy -conserving and loss -reducing.

The present application relates to a kind of maleic anhydride continuous hydrogenation preparation γ-butyrolactone and its preparation method.The prepared maleic anhydride solution and hydrogen are continuously introduced into the fixed bed containing nickel-copper catalyst to carry out hydrogenation reaction, the obtained crude product is introduced into separation column to carry out separation and purification, and γ-butyrolactone is obtained.The purity of the obtained γ-butyrolactone is ≥99.99%, and the rest is impurity;The impurity includes tetrahydrofuran and 1,4-butanediol;The content of tetrahydrofuran is ≤0.003%;The content of 1,4-butanediol is ≤0.004%.