A kind of medicine for treating limb edema and application thereof

A drug and limb technology, applied in the field of drugs for the treatment of limb edema, can solve the problems of poor lymphedema effect, achieve the effect of preventing skin tissue infection, reducing lymphedema and venous edema

Active Publication Date: 2011-12-28
SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned traditional Chinese medicine preparations are not effective in treating lymphedema

Method used

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  • A kind of medicine for treating limb edema and application thereof
  • A kind of medicine for treating limb edema and application thereof
  • A kind of medicine for treating limb edema and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Preparation of drug capsules for treating limb edema (1)

[0028] 1. Take Sophora flavescens 30kg (Sophora flavescens was purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), Scrophulariae 10kg (Scrophulariae scrophulariae was purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), Salvia miltiorrhiza 10kg (Salvia miltiorrhiza was purchased from Yunnan Yuxi Wanfang Natural Medicine Co., Ltd.) , crush the three herbs of Sophora flavescens, Scrophulariaceae, and Salvia miltiorrhiza,

[0029] 2. Soak with 10 times the amount of 80% ethanol for 30 minutes,

[0030] 3. Heat to reflux, extract three times, keep the first time for 2.5h, the second time for 2h, the third time for 1.5h, the temperature of each time is about 80°C,

[0031] 4. Combine the three extracts and concentrate under reduced pressure at a temperature of about 50°C to obtain a liquid extract.

[0032] 5. Drying under reduced pressure, temperature controlled at 50°C,

[0033] 6. Crush into fine p...

Embodiment 2

[0036] Preparation of drug capsules for treating limb edema (2)

[0037] 1. Take 50kg of Sophora flavescens (purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), 30kg of Scrophulariae (purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), 30kg of Salvia miltiorrhiza (purchased from Yunnan Yuxi Wanfang Natural Medicine Co., Ltd.) , crush the three herbs of Sophora flavescens, Scrophulariaceae, and Salvia miltiorrhiza,

[0038] 2. Soak with 10 times the amount of 80% ethanol for 30 minutes,

[0039] 3. Heat to reflux, extract three times, keep the first time for 2.5h, the second time for 2h, the third time for 1.5h, the temperature of each time is about 80°C,

[0040] 4. Combine the three extracts and concentrate under reduced pressure at a temperature of about 50°C to obtain a liquid extract.

[0041] 5. Drying under reduced pressure, temperature controlled at 50°C,

[0042] 6. Crush into fine powder (through 80 mesh sieve),

[0043] 7. Pack No. 2 capsules to pre...

Embodiment 3

[0045] Preparation of Drug Capsules for Treating Limb Edema (3)

[0046] 1. Take Sophora flavescens 70kg (Sophora flavescens was purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), Scrophulariae 10kg (Scrophulariae scrophulariae was purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), Salvia miltiorrhiza 20kg (Salvia miltiorrhiza was purchased from Yunnan Yuxi Wanfang Natural Medicine Co., Ltd.) , crush the three herbs of Sophora flavescens, Scrophulariaceae, and Salvia miltiorrhiza,

[0047] 2. Soak with 10 times the amount of 80% ethanol for 30 minutes,

[0048] 3. Heat to reflux, extract three times, keep the first time for 2.5h, the second time for 2h, the third time for 1.5h, the temperature of each time is about 80°C,

[0049] 4. Combine the three extracts and concentrate under reduced pressure at a temperature of about 50°C to obtain a liquid extract.

[0050] 5. Drying under reduced pressure, temperature controlled at 50°C,

[0051] 6. Crush into fine p...

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Abstract

The invention relates to a medicament for treating limb edema. The medicament is mainly prepared from the following crude drugs in parts by weight: 5-7 parts of Sophora flavescens, 1-3 parts of Scrophulariaceae, and 1-3 parts of Salvia miltiorrhiza. The invention also discloses the use of the drug for treating limb edema. The advantages of the present invention are: the drug for treating limb edema belongs to the compound preparation of traditional Chinese medicine, and its compatibility conforms to the principle of "junchenzuoshi" of traditional Chinese medicine. It is verified by pharmacodynamic experiments that the drug can significantly reduce lymphedema and venous edema of patients, and prevent and treat skin tissue infection. , skin, subcutaneous tissue hyperplasia and fibrosis complications. Sophora flavescens, scrophulariaceae and salvia miltiorrhiza in the medicine for treating limb edema have obvious synergistic effect, the invention is suitable for long-term administration, and is a safe and effective medicine for treating limb edema.

Description

【Technical field】 [0001] The invention relates to a medicine for treating limb edema and application thereof. Specifically, it is a Chinese patent medicine prepared from Chinese herbal medicines. 【Background technique】 [0002] Lymphatic circulation disorder, represented by chronic lymphedema of limbs, is a common medical problem. According to incomplete statistics, there are more than ten million patients with lymphedema in my country. Lymphatic circulation is one of the physiological and functional systemic circulations of the human body. Lymph is the interstitial fluid in the interstitial spaces that flows back into the veins through the lymphatic vessels. Limb lymphedema is commonly known as elephantiasis. The reason is that lymphatic drainage is blocked, and fluid and protein in the superficial soft tissue accumulate sharply. The high concentration of protein increases the osmotic pressure of the limbs in the tissue, thereby forming edema and leading to secondary infl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/808A61P7/10A61P9/00A61P17/00
Inventor 刘宁飞张俊平
Owner SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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