The invention belongs to the technical field of wine processing, and more specifically relates to a dandelion health-care wine containing cordyceps sinensis fungus powder and mythic fungus spore powder. A preparation method comprises following steps: 1, dandelion is mixed with honey water, fermented cordyceps sinensis fungus powder and wall-broken mythic fungus spore powder are added, and sulfur adjusting and acidity adjusting are carried out, a yeast expanding liquid and a fermentation auxiliary agent are added for fermentation, wine legs are separated, a second time of sulfur adjusting and acidity adjusting are carried out, bentonite refrigeration treatment is carried out, and the alcohol degree of an obtained wine solution is adjusted to a needed value so as to obtain a finished product. according to the preparation method, 1, honey is adopted to replace cane sugar, production period is shortened, the obtained product is more abundant in nutrients, and better in mouthfeel; 2, cordyceps sinensis fungus powder is taken as raw material for secondary fermentation, and active components in cordyceps sinensis fungus powder are released as far as possible; and 3, the dandelion health-care wine is prepared through mixing fermentation taking dandelion, fermented cordyceps sinensis fungus powder, wall-broken mythic fungus spore powder, and honey as main raw materials, so that the effects of the raw materials are achieved, and problems in the prior such as poor function of traditional medical wine, and single eating method of cordyceps sinensis fungus powder and mythic fungus sporepowder are solved.