Traditional Chinese medicine peptide for treating poultry colibacillosis and preparation method thereof

The technology of colibacillosis and traditional Chinese medicine is applied in the field of traditional Chinese medicine peptides for treating poultry colibacillosis and the preparation field thereof, which can solve the problems that traditional Chinese medicine prescriptions injure the internal organs of poultry, and achieve the effects of good therapeutic effect, short production cycle and fast onset of effect.

Inactive Publication Date: 2019-03-08
河北肽都生物科技集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the problem of drug resistance and food safety caused by existing antibiotics, and the problem that traditional Chinese medicine prescriptions damage poultry viscera, the invention provides a traditional Chinese medicine peptide for treating poultry colibacillosis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] This example provides a traditional Chinese medicine peptide for treating poultry colibacillosis. The raw materials include the following components by weight: 400g of dandelion, 600g of forsythia, 300g of honeysuckle, 300g of red peony, 200g of skullcap, 200g of bupleurum, and licorice 300g and raw garlic 100g. Its preparation method specifically comprises the following steps:

[0028] Step a. Weigh the above raw materials, steam dandelion, forsythia, honeysuckle, red peony, baicalin and Bupleurum for 1 hour respectively, add licorice and 12L of purified water, stir evenly, cook at 90°C for 2 hours, then add raw garlic, Continue to cook for 0.5h;

[0029] Step b, lower the temperature to 56°C, add 24g of amylase (obtained from the fermentation of Aspergillus niger) and 12g of Aspergillus oryzae protease and stir at 56°C for 2.5 hours. After the enzymolysis is completed, heat up to 90°C and keep for 10 minutes to kill the enzyme;

[0030] Step c, use a decanter centri...

Embodiment 2

[0033] This example provides a traditional Chinese medicine peptide for treating poultry colibacillosis. The raw materials include the following components by weight: 6 kg of dandelion, 4 kg of forsythia, 4 kg of honeysuckle, 2 kg of red peony, 3 kg of skullcap, 3 kg of bupleurum, and licorice 2kg and raw garlic 1.5kg. Its preparation method specifically comprises the following steps:

[0034] Step a. Weigh the above raw materials, steam dandelion, forsythia, honeysuckle, red peony, baicalin and Bupleurum for 1.5 hours respectively, add licorice and 150L of purified water, stir well, cook at 95°C for 3 hours, and then add raw garlic , continue to cook for 0.5h;

[0035] Step b, lower the temperature to 57°C, add 306g of amylase (obtained by fermentation of Aspergillus niger) and 153g of Aspergillus oryzae protease, stir at 57°C for 3 hours, after the enzymolysis is completed, heat up to 92°C, and keep for 15 minutes to kill the enzyme;

[0036] Step c, use a decanter centrif...

Embodiment 3

[0039] This example provides a traditional Chinese medicine peptide for treating poultry colibacillosis. The raw materials include the following components by weight: 8 kg of dandelion, 8 kg of forsythia, 6 kg of honeysuckle, 4 kg of red peony, 4 kg of skullcap, 4 kg of bupleurum, and licorice 4kg and raw garlic 2kg. Its preparation method specifically comprises the following steps:

[0040] Step a. Weigh the above raw materials, steam dandelion, forsythia, honeysuckle, red peony root, baicalin and Bupleurum for 1.5 hours respectively, add licorice and 238L of purified water, stir evenly, cook at 92°C for 2.5 hours, and then add raw Garlic, continue to cook for 0.7h;

[0041] Step b, lower the temperature to 57°C, add 500g of amylase (obtained from the fermentation of Aspergillus niger) and 250g of Aspergillus oryzae protease, stir at 57°C for 3 hours for enzymolysis, after the enzymolysis is completed, heat up to 92°C, and keep for 12 minutes to kill the enzyme;

[0042] Step...

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PUM

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Abstract

The invention relates to the technical field of veterinary medicine, in particular to traditional Chinese medicine peptide for treating poultry colibacillosis and a preparation method thereof. The traditional Chinese medicine peptide is prepared from the following raw materials: herba taraxaci, fructus forsythia, honeysuckle flower, radix paeoniae rubra, radix scutellariae, radix bupleuri, licorice roots and raw garlics. Eight kinds of traditional Chinese medicine are combined to be used; the effect of treating the poultry colibacillosis can be achieved without using antibiotics; the damage tothe internal organs of poultry is small. The preparation method is characterized in that the herba taraxaci, fructus forsythia, honeysuckle flower, radix paeoniae rubra, radix scutellariae and radixbupleuri are respectively processed by an evaporation method, and are then boiled together with water and the licorice roots; then, the raw garlics are added to be boiled together; after the enzymolysis by amylase and neutral protease, solid liquid separation, purification, concentration and drying are performed; the traditional Chinese medicine peptide is obtained. The production period of the preparation method is short; the cost is low; no any toxic and harmful substances are generated; the product prepared by the preparation method can be well absorbed; the effect taking is fast; a good treatment effect can be achieved without using large doses.

Description

technical field [0001] The invention relates to the technical field of veterinary medicine, in particular to a traditional Chinese medicine peptide for treating poultry colibacillosis and a preparation method thereof. Background technique [0002] Colibacillosis is a group of infectious diseases caused by pathogenic Escherichia coli (abbreviated as Escherichia coli). At present, there are mainly pig colibacillosis, poultry colibacillosis and rabbit colibacillosis that seriously endanger the breeding industry. Avian colibacillosis is caused by multiple serotypes of pathogenic Escherichia coli, which can lead to the death of embryos and young chicks, and lead to intestinal mucosal bleeding and ulcers, as well as E. coli granuloma, omphalitis, synovitis , Ophthalmia, sepsis, air sacculitis, pericarditis, salpingitis, enteritis, yolk peritonitis, etc. After the poultry is sick, they may appear listless, eat less or not eat, abdominal distension, yellow-green loose stools, rough...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61P31/04
CPCA61K36/233A61K36/288A61K36/355A61K36/484A61K36/539A61K36/634A61K36/65A61K36/71A61K36/8962A61K2236/19A61K2236/331A61P31/04A61K2300/00
Inventor 张晓东杨广杨子丰
Owner 河北肽都生物科技集团有限公司
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