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Medicament for treating lymphedema and venous edema and application thereof

A lymphedema and drug technology, applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of poor lymphedema effect, prevent skin tissue infection, reduce lymphedema, and have less toxic and side effects Effect

Inactive Publication Date: 2010-09-29
SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned traditional Chinese medicine preparations are not effective in treating lymphedema
And oral administration of the above-mentioned traditional Chinese medicine preparations is prone to gastric side effects

Method used

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  • Medicament for treating lymphedema and venous edema and application thereof
  • Medicament for treating lymphedema and venous edema and application thereof
  • Medicament for treating lymphedema and venous edema and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Preparation of drug capsules for treating lymphedema and venous edema (1)

[0031] 1. Take Sophora flavescens 30kg (Sophora flavescens was purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), Scrophulariae 10kg (Scrophulariae scrophulariae was purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), Salvia miltiorrhiza 10kg (Salvia miltiorrhiza was purchased from Yunnan Yuxi Wanfang Natural Medicine Co., Ltd.) , crush the three herbs of Sophora flavescens, Scrophulariaceae, and Salvia miltiorrhiza,

[0032] 2. Soak with 10 times the amount of 80% ethanol for 30 minutes,

[0033] 3. Heat to reflux, extract three times, keep the first time for 2.5h, the second time for 2h, the third time for 1.5h, the temperature of each time is about 80°C,

[0034] 4. Combine the three extracts and concentrate under reduced pressure at a temperature of about 50°C to obtain a liquid extract.

[0035] 5. Drying under reduced pressure, temperature controlled at 50°C,

[0036] 6. ...

Embodiment 2

[0043] Preparation of drug capsules for treating lymphedema and venous edema (2)

[0044] 1. Take 50kg of Sophora flavescens (purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), 30kg of Scrophulariae (purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), 30kg of Salvia miltiorrhiza (purchased from Yunnan Yuxi Wanfang Natural Medicine Co., Ltd.) , crush the three herbs of Sophora flavescens, Scrophulariaceae, and Salvia miltiorrhiza,

[0045] 2. Soak with 10 times the amount of 80% ethanol for 30 minutes,

[0046] 3. Heat to reflux, extract three times, keep the first time for 2.5h, the second time for 2h, the third time for 1.5h, the temperature of each time is about 80°C,

[0047] 4. Combine the three extracts and concentrate under reduced pressure at a temperature of about 50°C to obtain a liquid extract.

[0048] 5. Drying under reduced pressure, temperature controlled at 50°C,

[0049] 6. Crush into fine powder (through 80 mesh sieve),

[0050] 7. Take 20kg...

Embodiment 3

[0056] Preparation of drug capsules for treating lymphedema and venous edema (Ⅲ)

[0057] 1. Take Sophora flavescens 70kg (Sophora flavescens was purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), Scrophulariae 10kg (Scrophulariae scrophulariae was purchased from Ningxia Bauhinia Pharmaceutical Co., Ltd.), Salvia miltiorrhiza 20kg (Salvia miltiorrhiza was purchased from Yunnan Yuxi Wanfang Natural Medicine Co., Ltd.) , crush the three herbs of Sophora flavescens, Scrophulariaceae, and Salvia miltiorrhiza,

[0058] 2. Soak with 10 times the amount of 80% ethanol for 30 minutes,

[0059]3. Heat to reflux, extract three times, keep the first time for 2.5h, the second time for 2h, the third time for 1.5h, the temperature of each time is about 80°C,

[0060] 4. Combine the three extracts and concentrate under reduced pressure at a temperature of about 50°C to obtain a liquid extract.

[0061] 5. Drying under reduced pressure, temperature controlled at 50°C,

[0062] 6. C...

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Abstract

The invention relates to a medicament for treating lymphedema and venous edema. The medicament is mainly prepared from the following raw material medicaments in part by weight: 20 to 40 parts of lightyellow sophora root, 5 to 15 parts of figwort root, 5 to 15 parts of root of red-rooted salvia and 5 to 15 parts of ginger. The invention also discloses application of the medicament for treating the lymphedema and the venous edema. The invention belongs to a Chinese medicinal compound preparation, and the compatibility meets the principle of monarch, minister, assistant and guide of Chinese medicaments. Pharmacodynamic experiments prove that the medicament can obviously reduce the lymphedema and the venous edema of patients, and prevent and treat skin tissue infection, hyperblastosis of skin and hypoderm and fibrosis complication. The lightyellow sophora root, the figwort root and the root red-rooted salvia in the medicament for treating the lymphedema and the venous edema have obvious synergistic effects; the ginger can reduce coldness of the medicaments; and fructus amomi has the effects of nourishing stomach. Therefore, the medicament reduces the side effects of stomach discomfort when improving curative effects. The medicament has small side effects, is suitable for long-term use, and is the safe and effective medicament for treating the lymphedema.

Description

【Technical field】 [0001] The invention relates to a medicine for treating lymphedema and venous edema and application thereof. Specifically, it is a Chinese patent medicine prepared from Chinese herbal medicines. 【Background technique】 [0002] Lymphatic circulation is one of the physiological and functional systemic circulations of the human body. Lymph is the interstitial fluid in the interstitial spaces that flows back into the veins through the lymphatic vessels. Limb lymphedema is commonly known as elephantiasis. The reason is that lymphatic drainage is blocked, and fluid and protein in the superficial soft tissue accumulate sharply. The high concentration of protein increases the osmotic pressure of the limbs in the tissue, thereby forming edema and leading to secondary inflammation. It makes the fascia and skin thickened and rough, the patient's limbs are bloated, and it is inconvenient to walk. Some patients have repeated attacks of erysipelas-like inflammation, c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P7/10A61P9/00A61P17/00
Inventor 刘宁飞
Owner SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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