Adaptive sealed reaction chamber for biochip reaction device

A self-adaptive sealing and biochip technology, which is applied in the field of biological analysis, can solve the problems of different volumes, deformation, and poor sealing of biochip reaction chambers, and achieve the effects of convenient observation, avoiding poor sealing, and easy cleaning

Active Publication Date: 2012-08-01
SHANGHAI BAIO TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] In view of the fact that when multiple biochips in the prior art need to react at the same time, the flat platen will be deformed when the pressure is applied by the lifting knob, resulting in proble

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  • Adaptive sealed reaction chamber for biochip reaction device
  • Adaptive sealed reaction chamber for biochip reaction device
  • Adaptive sealed reaction chamber for biochip reaction device

Examples

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[0020] The technical solutions of the present invention are further described below with reference to the accompanying drawings and embodiments.

[0021] see figure 1 , image 3 , Figure 4 , Figure 5 The shown adaptive sealed reaction chamber 12 for the biochip reaction device is provided on the chip carrier 111, and the chip carrier 111 is provided on the carrier 11 (see figure 2 ), the above-mentioned self-adaptive sealed reaction chambers have a total of 2 groups, each group of self-adapted sealed reaction chambers 12 includes a chip positioning frame 121 and a reaction chamber press cover 122, and the reaction chamber press cover 122 is provided above the chip positioning frame 121 . The chip positioning frame 121 is provided with four chip slots 123 , and the number of the chip slots can also be changed according to requirements. The chip slots 123 are provided with biochips 124 . The reaction chamber gland 122 includes a casing 125 and an adaptive module 126 (for...

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Abstract

The invention discloses an adaptive sealed reaction chamber for a biochip reaction device, which comprises a chip positioning frame and a reaction chamber gland. A plurality of chip notches are arranged in the chip positioning frame, and the reaction chamber gland comprises a shell, an adaptive module, a compression bar, compression springs and a sealing ring. When a plurality of biochips in the adaptive sealed reaction chamber need simultaneous reaction, the compression spring positioned above each biochip is used for adjusting the adaptive module, a reaction cavity of each biochip can be independently and effectively sealed, the sizes of the reaction cavities of the biochip in the same reaction chamber are identical, and the problems of untightness, leakage and the like are avoided. Moreover, as the reaction chamber has an openable structure, an operator not only can conveniently observe cleaning conditions in the reaction cavities, but also can conveniently clean the reaction cavities.

Description

technical field [0001] The invention relates to the field of bioanalysis, and more specifically relates to an self-adaptive sealed reaction chamber for a biochip reaction device. Background technique [0002] Biochip refers to the orderly immobilization of gene probes (oligonucleotide probes, cDNA clones, PCR products, etc.), antigen antibodies, tissue sections, cells, etc., which can reflect a large amount of biological information in the sample, on a solid support ( Such as active molecule modified glass slides or silicon wafers, nylon membranes, nitrocellulose membranes, etc.). By reacting with actual samples, biochips can obtain high-throughput information on biomolecules such as genes and proteins to be tested. It is widely used in medical clinical testing, pharmacology, and new drug development. [0003] In order to standardize and standardize the experimental operation of biochips, reduce human errors, and improve the stability and reproducibility of test results, t...

Claims

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Application Information

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IPC IPC(8): C12M1/00C12M1/38G01N33/50
CPCC12M23/58C12M23/44C12M23/38
Inventor 朱滨邢军芬王宪华姚克迪覃水记戴斌
Owner SHANGHAI BAIO TECH
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