Adaptive sealed reaction chamber for biochip reaction device

Abstract

The invention discloses an adaptive sealed reaction chamber for a biochip reaction device, which comprises a chip positioning frame and a reaction chamber gland. A plurality of chip notches are arranged in the chip positioning frame, and the reaction chamber gland comprises a shell, an adaptive module, a compression bar, compression springs and a sealing ring. When a plurality of biochips in the adaptive sealed reaction chamber need simultaneous reaction, the compression spring positioned above each biochip is used for adjusting the adaptive module, a reaction cavity of each biochip can be independently and effectively sealed, the sizes of the reaction cavities of the biochip in the same reaction chamber are identical, and the problems of untightness, leakage and the like are avoided. Moreover, as the reaction chamber has an openable structure, an operator not only can conveniently observe cleaning conditions in the reaction cavities, but also can conveniently clean the reaction cavities.

Description

technical field [0001] The invention relates to the field of bioanalysis, and more specifically relates to an self-adaptive sealed reaction chamber for a biochip reaction device. Background technique [0002] Biochip refers to the orderly immobilization of gene probes (oligonucleotide probes, cDNA clones, PCR products, etc.), antigen antibodies, tissue sections, cells, etc., which can reflect a large amount of biological information in the sample, on a solid support ( Such as active molecule modified glass slides or silicon wafers, nylon membranes, nitrocellulose membranes, etc.). By reacting with actual samples, biochips can obtain high-throughput information on biomolecules such as genes and proteins to be tested. It is widely used in medical clinical testing, pharmacology, and new drug development. [0003] In order to standardize and standardize the experimental operation of biochips, reduce human errors, and improve the stability and reproducibility of test results, t...

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Problems solved by technology

[0004] In view of the fact that when multiple biochips in the prior art need to react at the same time, the flat platen will be deformed when the pressure is applied by the lifting knob, resulting in problems such as poor sealing and different volumes of the reaction chambers of the biochips. The purpose of the present invention is to provide A self-adaptive sealed reaction chamber for biochip reaction device

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