Optimized platelet aggregation function detection analysis method suitable for automated instrument

A technology of platelet aggregation and analysis method, which is applied in the field of platelet aggregation function detection, and can solve problems such as failing to reach a high level of detection repeatability

Inactive Publication Date: 2013-07-10
SINNOWA MEDICAL SCI & TECH
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

However, due to the relatively simple method for the detection of platelet aggregation function using a hematology analyzer, it has not yet reached a high level of detection repeatability

Method used

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  • Optimized platelet aggregation function detection analysis method suitable for automated instrument
  • Optimized platelet aggregation function detection analysis method suitable for automated instrument
  • Optimized platelet aggregation function detection analysis method suitable for automated instrument

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Embodiment Construction

[0005] The detection and analysis process of the method of the present invention is as follows: the prepared anticoagulated blood sample to be tested is kept at a constant temperature and fully mixed, and then the number of platelets in the secondary blood sample is detected. For comparison, if the difference between the two data is not more than 10% of the average value, then the average value is used as the benchmark value of the platelet value detected this time. However, if the difference between the two data is greater than 10% of the other value, the blood sample should be tested again. If the result of the retest is close to any of the two previously tested data, that is, the difference between the results and one of the results If it does not exceed 10%, the average value of these two data will be used as the benchmark value for this detection. Subsequently, add the aggregation inducer to the blood sample at a ratio of 9:1 (blood: aggregation inducer), mix well, and co...

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Abstract

An optimized platelet aggregation function detection analysis method suitable for automated instrument belongs to the field of clinical laboratory medicine. The method is an improvement and optimization of an automatic counting detection method for detection analysis of platelet aggregation function. The process is applicable to platelet aggregation function automated analytical instrument employing a counting method. The method detects and records the amount of platelet and calculates aggregation rate. Test results by the laboratory show that the repeatability of the platelet aggregation rate result obtained by the method is superior to that of a prior maximum aggregation rate method.

Description

1. Technical field [0001] The present invention relates to a process and analysis of a platelet aggregation function test which is suitable for an automatic instrument, by automatically measuring the change of the number of platelets in a blood sample before and after aggregation, and automatically analyzing and calculating according to the change data to obtain the platelet aggregation function evaluation of the tested blood sample The method belongs to the field of clinical laboratory medicine. 2. Background technology [0002] Platelet aggregation function (or aggregation rate) is an important function of platelets in blood and an important index for evaluating blood coagulation function. The existing detection method of platelet aggregation function is mainly by detecting the change of optical density (or light flux performance) in plasma (whole blood) before and after platelet aggregation in plasma or whole blood (abbreviation: optical method), or putting electrodes int...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/49
Inventor 徐新董自权曹宁周强
Owner SINNOWA MEDICAL SCI & TECH
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