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53 results about "Automated analyser" patented technology

An automated analyser is a medical laboratory instrument designed to measure different chemicals and other characteristics in a number of biological samples quickly, with minimal human assistance. These measured properties of blood and other fluids may be useful in the diagnosis of disease.

Automated process for isolating and amplifying a target nucleic acid sequence

InactiveUS20050130198A1Efficient and high through-put operationEfficient comprehensive utilizationRotating receptacle mixersBioreactor/fermenter combinationsIsolation proceduresTemperature control
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
Owner:GEN PROBE INC

Containers for reducing or eliminating foaming

A foam reducing or eliminating container for containing a liquid includes: a container body having a top portion, a bottom portion and an opening for adding a liquid to or removing a liquid from the container body; and a hollow baffle located within the container with first and second openings therein. The first and second openings are covered with a pierceable seal, wherein the first opening of the baffle is at least partially aligned with the opening of the container. In a preferred embodiment, the container is a reagent supply container for an automated analyzer, which includes: a container as described above; and a closure which is movable away from the opening of the container to be in an open position and movable into contact with the opening to be in a closed position. In another preferred embodiment a reagent supply for an automated analyzer includes: the reagent supply container as described above; and a liquid reagent therein. The second opening of the baffle is submerged in liquid. A method for reducing or eliminating the aspiration of foam into a metering probe includes: providing a reagent supply as described above; providing a metering probe movable in a direction toward and away from the reagent supply; moving the closure away from the opening of the container; piercing both seals covering the first and second openings of the baffle allowing liquid to enter the baffle from the end of the baffle submerged in the liquid, wherein the seals may or may not be pierced with the metering probe; moving the metering probe into the first opening of the baffle and into contact with the liquid in the baffle; aspirating a selected amount of liquid in the baffle; and moving the metering probe out of the baffle.
Owner:ORTHO-CLINICAL DIAGNOSTICS

System and Method for Incubating the Contents of A Reaction Receptacle

InactiveUS20080089818A1Efficient and high through-put operationEfficient comprehensive utilizationBioreactor/fermenter combinationsHeating or cooling apparatusIsolation proceduresTemperature control
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
Owner:GEN PROBE INC

Kit and method for detecting concentration of complement Clq in human serum

The invention belongs to the field of biological engineering, and provides a kit for detecting the concentration of a complement Clq in human serum by an immune transmission turbidimetry and an immune scattering turbidimetry. The kit solves the technical problems that an immune diffusion method and an enzyme-linked immune sorbent assay (ELISA) double antibody sandwich technology for measuring theconcentration of the complement Clq have complicated steps and are low in accuracy and repeatability in the prior art. The kit comprises two reagents, wherein a first reagent consists of disodium hydrogen phosphate, monopotassium phosphate, polyethylene glycol 6000 (PEG6000), ethylene diamine tetraacetic acid (EDTA)-NA2 and TX-100; and a second reagent consists of the disodium hydrogen phosphate,the monopotassium phosphate, the PEG 6000, the EDTA-NA2, the TX-100 and rabbit antihuman complement Clq antiserum. The invention also provides a method for detecting the concentration of the complement Clq in the human serum by using the kit. The kit and the method for measuring the concentration of the complement Clq have simple and convenient steps, are high in accuracy and repeatability and are used for automated analysis meters.
Owner:上海北加生化试剂有限公司

Mixer and circulating type photometric testing automatic analyzer

A mixer and a circulating type photometric testing automatic analyzer are used for testing specific components of solutions or studying on chemical reaction dynamics. The mixer comprises a liquid inlet tube, a mixer body, an upper liquid outlet pipe communicated with the inner cavity of the mixer body and a lower liquid outlet pipe communicated with the inner cavity of the mixer body. One end of the liquid inlet pipe is vertically inserted into the inner cavity from bottom to top and is communicated with the inner cavity, the upper liquid outlet pipe is connected with the top portion of the mixer body, and the lower liquid outlet pipe is connected with the bottom of the mixer body. The automatic analyzer further comprises a mixer, an automatic injection valve, a reagent selector value, a three-way valve, a reagent pump, a water sample pump, a multi-channel switching valve, a reagent quantitative loop, a spectrophotometric detector and a control circuit. By the adoption of the automatic analyzer, the photometric testing is not interfered by air bubbles in a flow path, automation degree is high, the automatic sample feeding and the on-line mixing are added, no reagents need to be added repeatability, the utilization rate of reagents is improved efficiently, operation is flexible, the degree of reaction can be controlled by adjusting the mixing time, and the sensitivity can be adjusted to meet the measurement requirements of target objects with different concentrations.
Owner:XIAMEN UNIV

Pipeline interchange/transmix

In one embodiment, a process is taught where the process begins by flowing a first product through a first pipeline and flowing a second product through a second pipeline. In this embodiment, the first product in the first pipeline is analyzed with a first product automated analyzer that is capable of physical and/or chemically analyzing the first product in the first pipeline and generating a first product data. Additionally, in this embodiment, the second product in the second pipeline is analyzed with a second product automated analyzer that is capable of physical and/or chemically analyzing the second product in the second pipeline and generating a second product data. The process then produces a blended product by mixing both the first product and the second product within a pipeline interchange which is connected downstream to both the first pipeline and the second pipeline. The blended product then flows from the pipeline interchange to a third pipeline that is connected downstream of pipeline interchange. The first product data and the second product data is then interpreted in a data analyzer by comparing the physical and/or chemical characteristics of the physical and/or chemical characteristics of the first data to an optimal first data and the physical and/or chemical characteristics of the second data to an optimal second data. The data analyzer then determines the adjustments in the flow of the first product and the flow of the second product to achieve optimal blended data from the blended product. The adjustments are then communicated to adjust the flow of the first product in the first pipeline and the flow of the second product in the second pipeline.
Owner:PHILLIPS 66 CO
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