Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for extracting anti-cerebral-ischemia material from roses and application of anti-cerebral ischemia material

An anti-cerebral ischemia and rosette technology, applied in the field of medicine, can solve the problem of unclear specific active components of anti-cerebral ischemia, and achieve the effects of improving medicinal value, easy preparation and abundant raw materials

Inactive Publication Date: 2015-01-14
HENAN UNIV OF CHINESE MEDICINE
View PDF1 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But up to now, no report of roses on cerebral ischemia has been found, and the specific active ingredients against cerebral ischemia are still unclear. The main active ingredients in rose alcohol extract are total flavonoids, and how to extract total flavonoids from roses, As yet no public reports

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for extracting anti-cerebral-ischemia material from roses and application of anti-cerebral ischemia material
  • Method for extracting anti-cerebral-ischemia material from roses and application of anti-cerebral ischemia material
  • Method for extracting anti-cerebral-ischemia material from roses and application of anti-cerebral ischemia material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0010] Below in conjunction with specific circumstances, the specific embodiment of the present invention will be described in detail.

[0011] The present invention is realized by the following concrete methods in concrete implementation: the rose is pulverized into the medicine powder of crossing 60-80 mesh sieve, degreases with the sherwood oil of 10 times medicine powder weight reflux extraction 1h; The rose medicine powder filter residue after degreasing, The petroleum ether was evaporated until dry to obtain rose pollen; the rose pollen was soaked in ethanol with 10 times the weight of the pollen and a volume concentration of 60% for 0.5 h, refluxed twice for 1 h each time to obtain the extract, filtered, and the ethanol recovered under reduced pressure to No alcohol smell, concentrated to a concentrated solution with a relative density of 1.1-1.4, the concentrated solution is dispersed with distilled water to a sample solution equivalent to a crude drug content of 0.3g / m...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the method for extracting an anti-cerebral-ischemia material from roses and the application of the anti-cerebral-ischemia material. The problem of extraction of the anti-cerebral-ischemia material from the roses can be effectively solved and the application of rose extractive in preparation of anti-cerebral-ischemia medicine is achieved. The method comprises the following steps that the roses are smashed into medicine powder, and reflux extraction is conducted on the medicine powder through petroleum ether for one hour so that degreasing is completed; residue of the degreased rose medicine powder is filtered out, the petroleum ether is volatilized until the rose medicine powder is dry, and therefore rose powder is obtained; the rose powder is soaked with ethyl alcohol, reflux retraction is conducted for two times, extractive liquid is filtered, decompression is conduced so that the ethyl alcohol can be recycled until the smell of the ethyl alcohol does not exist, concentration is conducted, and distilled water is added to concentration liquid so that the concentration liquid can be dispersed into sample liquid; AB-8 type macroporous resin on the sample liquid is eluted through distilled water, and water liquid is removed; elution is conducted through ethyl alcohol, decompression is conducted so that ethyl alcohol can be recycled, concentration is conducted on the sample liquid until dry powder is obtained, and rose general flavone is obtained. The rose general flavone can be effectively used for preparation of the anti-cerebral-ischemia medicine, and the application of the rose extractive in the preparation of the anti-cerebral-ischemia medicine is achieved. According to the method for extracting the anti-cerebral-ischemia material from roses and the application of the anti-cerebral-ischemia material, raw materials are abundant, the anti-cerebral-ischemia material is easy to prepare, the extractive has the anti-cerebral-ischemia function, and the anti-cerebral-ischemia material is innovation of medicine.

Description

technical field [0001] The invention relates to medicine, in particular to a method for extracting anti-cerebral ischemia substances from roses and its application. Background technique [0002] Ischemic cerebrovascular disease belongs to the scope of "ischemic stroke" in traditional Chinese medicine. It is a focal brain dysfunction caused by insufficient or interrupted local cerebral blood supply and oxygen supply. The common ones are transient ischemic attack, cerebral embolism, cerebral Thrombosis is a common and frequently-occurring disease that seriously threatens human life and health, and it is the main disease that causes death and disability. Ischemia-reperfusion injury (IRI) refers to the pathological phenomenon in which tissue damage is aggravated after a certain period of ischemia and blood supply is restored. At present, the intervention of drugs on ischemic brain injury has become an important research topic concerned by the society and the medical field, and ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/738A61P9/10
Inventor 苗明三宰炎冰
Owner HENAN UNIV OF CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products