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A kind of medicine for treating skin squamous cell carcinoma and preparation method thereof

A squamous cell carcinoma and drug technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as pain, pigmentation, redness and swelling of the skin

Active Publication Date: 2016-08-17
遵义医药高等专科学校
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the course of radiation therapy is long, and there is a potential risk of temporary skin redness, pain, and even ulceration; it can also lead to pigmentation, damage to surrounding tissues such as sweat glands, alopecia areata, and scar deterioration.
3 Drug treatment: Currently, there are imiquimod cream, 5-fluorouracil ointment, interferon injection, Bec-5 ointment, Pingyangmycin, cisplatin and other drugs for chemotherapy, but skin redness, pain, desquamation, and hardening are common Scab and other side effects
Laser treatment can be used alone or in combination with surgery, which is less time-consuming, but it needs to be done by a specialist, so it is expensive

Method used

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  • A kind of medicine for treating skin squamous cell carcinoma and preparation method thereof
  • A kind of medicine for treating skin squamous cell carcinoma and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A preparation method for a medicine for treating squamous cell carcinoma of the skin, comprising the steps of:

[0020] (1) 5 parts of pulsatilla, 3 parts of curcuma, and 2 parts of ginger, add 12 times the weight of medicinal materials and 70% ethanol to extract three times, each time for 2 hours;

[0021] (2) Combine the filtrates, concentrate them into a 1:1.3 liquid extract, dry them in a 65-75°C incubator until they become hard and brittle, and store them in low-temperature drying.

Embodiment 2

[0023] A preparation method for a medicine for treating squamous cell carcinoma of the skin, comprising the steps of:

[0024] (1) 4 parts of pulsatilla, 4 parts of curcuma, and 1 part of ginger, add 12 times the weight of medicinal materials and 70% ethanol to extract three times, each time for 2 hours;

[0025] (2) Combine the filtrates, concentrate them into a 1:1.3 liquid extract, dry them in a 65-75°C incubator until they become hard and brittle, and store them in low-temperature drying.

Embodiment 3

[0027] A preparation method for a medicine for treating squamous cell carcinoma of the skin, comprising the steps of:

[0028] (1) 6 parts of Pulsatilla chinensis, 2 parts of curcuma, and 2 parts of ginger, add 12 times the weight of medicinal materials and 70% ethanol to extract three times, each time for 2 hours;

[0029] (2) Combine the filtrates, concentrate them into a 1:1.3 liquid extract, dry them in a 65-75°C incubator until they become hard and brittle, and store them in low-temperature drying.

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Abstract

The invention discloses a medicine for treating skin squamous cell carcinoma and a preparation method thereof. The weight ratio of raw materials is as follows: 4-6 parts of pulsatilla, 2-4 parts of curcuma, and 1-3 parts of ginger. Add 12 times the weight of the medicinal materials and extract with 70% ethanol three times, each time for 2 hours; combine the filtrates, concentrate them into a 1:1.3 liquid extract, dry them in a 65-75°C thermostat until they become hard and brittle, dry and store at low temperature. have to. The invention can significantly inhibit the proliferation of skin squamous cell carcinoma A431 cells, and at the same time, it also has the obvious effect of inducing the apoptosis of A431 cells, and can prevent the cells from staying in the G0 / G1 phase, hinder the DNA synthesis in the S phase, and inhibit tumor cells proliferation.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating skin squamous cell carcinoma, and also relates to a preparation method of the medicine for treating skin squamous cell carcinoma. Background technique [0002] Skin squamous cell carcinoma (SCC) is a malignant tumor originating from epidermal or adnexal keratinocytes. Its incidence is second only to basal cell carcinoma in non-melanoma of the skin, accounting for about 20% of all non-melanoma. The incidence of squamous cell carcinoma of the skin has been increasing year by year in recent years. The disease develops rapidly and is destructive. Lymph node metastasis can occur, and visceral metastasis can occur in the late stage. Skin squamous cell carcinoma has become the main skin tumor that threatens human life. [0003] The existing treatment methods for squamous cell carcinoma of the skin mainly include the following: 1. Surgical tr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P35/00
Inventor 潘年松罗俊刘英波许俏
Owner 遵义医药高等专科学校
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