Preparation method of traditional Chinese preparation honeysuckle and radix scutellariae granules

A technology of traditional Chinese medicine preparations and granules, applied in the field of medicine, to achieve the effect of good solubility

Inactive Publication Date: 2014-06-04
QINGDAO KDN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The object of the present invention is to provide a preparation method of Chinese medicine preparation Yinhuang granules, which can improve the effective extraction rate of chlorogenic acid in honeysuckle and baicalin in Scutellaria baicalensis, solve the problems of granule solubility, thereby improving the yield of Yinhuang granules. efficacy and quality

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1: the preparation method prescription of granule: Scutellaria baicalensis 2008 honeysuckle 73g

[0024] Preparation method:

[0025] (1) Preparation of honeysuckle clear paste: honeysuckle is decocted twice, for the first time for 30 minutes, for the second time for 20 minutes, filtered, liquid-liquid concentrated under reduced pressure to a relative density of about 1.17, adding ethanol to make the alcohol content reach 65, stand still, recover ethanol, concentrate to a relative density of about 1.2-1.25.

[0026] (2) Preparation of Scutellaria baicalensis paste: Scutellaria baicalensis is added to boiling water and decocted twice, each time for 1 hour, filtered, and left to stand for 24 hours; take the supernatant and filter, add concentrated hydrochloric acid to the filtrate to adjust the pH value to 1.5-2.0, Incubate at 80°C for 1 hour and let stand for 24 hours. Filter the precipitate, add 5-10 times the amount of water and stir to dissolve, adjust th...

Embodiment 2

[0028] Embodiment 2: the preparation method of granule

[0029] Prescription: Scutellaria baicalensis 2208 honeysuckle 60g

[0030] Preparation method:

[0031] (1) Preparation of Quanyinhua clear cream: decoct the whole Yinhua with water twice, the first time for 30 minutes, the second time for 20 minutes, filter, liquid-liquid concentrated under reduced pressure to a relative density of about 1.17, add ethanol to make Alcohol content reaches 65%, stand still, recover ethanol, concentrate to a relative density of about 1. 2-1. 25 0

[0032] (2) Preparation of Scutellaria baicalensis paste: Scutellaria baicalensis is added to boiling water and decocted twice, each time for 1 hour, filtered, and left to stand for 24 hours; take the supernatant and filter, add concentrated hydrochloric acid to the filtrate to adjust the pH value to 1.5- 2. Incubate at 0, 80°C for 1 hour and let stand for 24 hours. Filter the precipitate, add 5-10 times the amount of water and stir to dissolve...

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Abstract

The invention relates to a preparation method of traditional Chinese preparation honeysuckle and radix scutellariae granules. The preparation method comprises the following steps of: (1) preparation of honeysuckle thin paste: decocting honeysuckle with water twice, filtering, concentrating under reduced pressure, adding ethanol, standing, recovering the ethanol, and concentrating; (2) preparation of radix scutellariae thin paste: decocting radix scutellariae with boiling water twice, filtering, standing, filtering supernatant, adjusting the pH value of the filtrate with concentrated hydrochloric acid, standing, filtering out precipitates, adding water to the precipitates, stirring for dissolving, adjusting the pH value with a sodium hydroxide solution, adding equivalent ethanol, uniformly stirring, standing, filtering supernatant, recovering ethanol from filtrate, and concentrating; and (3) adding a proper amount of adjuvants to the honeysuckle thin paste and radix scutellariae thin paste, uniformly stirring, and granulating.

Description

technical field [0001] The invention belongs to the field of medicine and relates to a preparation method of medicine, in particular to a new preparation method of Yinhuang Granules. Background technique [0002] Yinhuang granule is made of scutellaria baicalensis extract and honeysuckle extract plus appropriate amount of auxiliary materials. It has the functions of clearing away heat, detoxification and anti-inflammation. For acute and chronic tonsillitis, acute and chronic pharyngitis, upper respiratory tract infection. The existing silver yellow granule preparation method: decoct honeysuckle with water, filter, concentrate, add an appropriate amount of starch, stir well, and dry to obtain the honeysuckle extract. Scutellaria baicalensis is decocted with water, concentrated, and the concentrated solution is added with hydrochloric acid to adjust the pH value to 1-2, keep warm at 80°C, let it stand, filter the precipitate, add appropriate amount of water and st...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61K9/16A61P11/00A61P11/04
Inventor钟英杰郝智慧付海宁
OwnerQINGDAO KDN BIOTECH