Kit for evaluating 24-hour urinary sodium value of man
A 24-hour, kit-based technology, applied in the field of medicine, can solve problems such as cumbersome procedures, inconvenience for patients, and inconvenient intake of urinary sodium
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Embodiment 1
[0033] Embodiment 1, establishment of the inventive method
[0034] The data come from hypertensive patients hospitalized in the hypertension ward of Peking University People's Hospital from August 2011 to November 2012. Inclusion criteria: ①The diagnosis of hypertension was clear. The diagnostic criteria of hypertension were based on the 2010 Chinese guidelines for the prevention and treatment of hypertension. Hypertension was defined as systolic blood pressure ≥ 140mmHg (1mmHg = 0.133kPa) and (or) diastolic blood pressure ≥ 90mmHg when blood pressure was measured 3 times on different days without using antihypertensive drugs. The patient had a history of hypertension in the past and was currently using antihypertensive drugs. His blood pressure was <140 / 90mHg, and he was also diagnosed as hypertension. ② Stable regular diet in the past 1 month. ③ Fill in the informed consent. Exclusion criteria: ①Hypertension accompanied by severe multi-system diseases (such as rheumatic...
Embodiment 2
[0046] Embodiment 2, verification of the inventive method
[0047] There were 96 male patients in the verification group. The predicted value of urine sodium (e-24HUNa) was calculated by the Tanaka method and the SUN1 method respectively, and the accuracy of the predicted value and the measured value (r-24HUNa) were compared. The results are as follows: Table 1:
[0048] Table 1 Accuracy comparison of three methods
[0049]
[0050] P is the chi-square test value compared with the SUN1 method
[0051] It can be seen from Table 1 that the 30% accuracy of SUN1 method for estimating e-24HUNa is not statistically significant compared with T method (P>0.05), suggesting that the accuracy of SUN1 method and T method for estimating e-24HUNa are comparable.
[0052] figure 1 It is the Bland-Altman diagram of urine sodium predicted by T method based on spot urine sodium of PM samples and measured urine sodium.
[0053] figure 2 It is the Bland-Altman diagram of urine sodium pre...
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