59 results about "Urine Creatinine" patented technology

A continuous Glomerular Filtration Rate (GFR) estimation system may include a Foley catheter, a continuous urine creatinine sensor, and a urine output monitor. The continuous GFR estimation system computes creatinine clearance as CrCl=(Ucr×Uvol) / Pcr×Tmin), where Ucr is urine creatinine in mg / dL, Uvol is urine volume in mL, Pcr is plasma (serum) creatinine in mg / dL, and Tmin is time in minutes. A Foley catheter may be used to withdraw urine from the bladder. The urine may be delivered to a urine output monitor that provides the Uvol value over a time Tmin. Attached to the catheter is the flow-through continuous urine creatinine sensor for providing the Ucr value. The remaining parameter is Pcr. Because serum creatinine levels do not change rapidly over time, a blood sample may be withdrawn prior to the start of the continuous GFR to obtain the Pcr value.

The invention discloses application of carnosic acid and rosemary acid to jointly prepare a drug for prevention and treatment of type II diabetes nephropathy. According to the application, it is foundthat the carnosic acid and the rosemary acid with the quality ratio of 6:1 can significantly and synergistically reduce fasting blood glucose of a type II diabetic nephropathy mouse, can significantly and synergistically decrease the urinary protein excretion rate and increase the urinary creatinine content and has significant and synergetic improvement effect on the kidney function of the diabetes nephropathy mouse, and the synergetic effect is unexpected by the technicians in the field.

The invention discloses a urine microalbumin / urine creatinine detection kit. The kit comprises a urine creatinine detection reagent and a urine microalbumin detection reagent, wherein the urine creatinine detection reagent comprises a reagent R1 used for eliminating endogenous creatine and sarcosine, a reagent R2 used for converting creatinine into creatine and a luminescent substrate 1 used for detecting hydrogen peroxide; the urine microalbumin detection reagent comprises an immobilized rabbit-anti-human serum albumin polyclonal antibody, a reagent R3 used for binding urine microalbumin andthe immobilized rabbit-anti-human serum albumin polyclonal antibody, an alkaline phosphatase labelled reagent R4 used for binding with urine microalbumin and a luminescent substrate 2 used for detecting alkaline phosphatase. Urine microalbumin and urine creatinine are detected with a glow-type chemiluminiscence method; the detection method can detect two indexes on a chemiluminescence instrument and enables measurement to be more accurate, more convenient and rapider.

The invention relates to a urine analysis and test card for urine microalbumin / urine creatinine. The urine analysis and test card for the urine microalbumin / urine creatinine comprises a sample pad, wherein a loading hole is formed in the sample pad. The urine analysis and test card for the urine microalbumin / urine creatinine is characterized in that a urine microalbumin test card and a urine creatinine test card are arranged on the sample pad respectively; one end of the urine microalbumin test card and one end of the urine creatinine test card are connected with the loading hole respectively; an albumin detection line and a first quality control line are arranged on the urine microalbumin test card; the albumin detection line is positioned at the end near to the loading hole; a urine creatinine detection line and a second quality control line are arranged on the urine creatinine test card; the urine creatinine detection line is positioned at the end near to the loading hole; a first detection hole is formed in the back side of the urine microalbumin test card and at the position corresponding to the albumin detection line; a second detection hole is formed in the back side of the urine creatinine test card and at the position corresponding to the urine creatinine detection line. The urine analysis and test card for the urine microalbumin / urine creatinine can solve the problem of interference caused by the situation that urine protein is singly used as a detection index; a preparation method is simple, and easy to operate.

The invention provides a kit simultaneously detecting sodium and creatinine in urine. The kit comprises a reaction base plate possessing a sodium reactive hole and a creatinine reactive hole, a sodium diluent, a creatinine diluent and a standard shade guide; a substrate pad and an enzyme pad are placed in the sodium reactive hole from bottom to top, the substrate pad is prepared by dropwise adding a substrate solution on a carrier, and the enzyme pad contains a beta-galactosidase and an enzyme stabilizing agent; an upper pad and a lower pad are placed in the creatinine reactive hole from bottom to top, the lower pad is prepared by dropwise adding an enzyme solution and a color developing agent on a carrier, and the lower pad contains an peroxidase, a creatinine amide hydrolase, a color developing agent, a stabilizing agent and the like; and the standard shade guide comprises standard color development of different concentration sodium ion and standard color development of different concentration creatinine. The kit preparation method is simple, the kit is stable in performance and easy to store, the color intervals corresponding to different concentration urine sodium and creatinine are obvious, whether the salt content of a detected person exceeds standard is convenient to determine, and also the kit is applicable to hospital clinical laboratory and non-professional examination personnel.